Organic Semiconducting Nanoparticles for Biosensor: A Review
Abstract
:1. Introduction
2. In Vitro Tracking
2.1. Biological Small Molecules Tracking
2.2. Enzyme Concentration Measurement
2.3. Nucleic Acid Concentration Measurement
3. In Vivo Tracking
3.1. Tumor Localization
3.2. Blood Vessel Imaging
3.3. Particles Tracking
4. Conclusions and Outlook
Probe | Target | Emission Spectra (λem) (nm) | Excitation Spectra (λex) (nm) | Ref. |
---|---|---|---|---|
P-dot@MnO2 | GSH | 510 | 458 | [44] |
DQ-CD@Pdots | GSH | 541 | 450 | [45] |
FCPNPs-GSH, GNPs@PEI | GST | 500–600 | 470 | [53] |
PFO/CN-PPV@Tyr-OMe | TR | 586 | 380 | [60] |
MiRNA-122 Probe | MiRNA-122 | 543 | - | [72] |
L-Pdots | MiRNA-21 | 425 | - | [73] |
N-Pdots | MiRNA-205 | 672 | - | [73] |
PF-DNAP CPNs | ssDNAC | 530 | 390 | [80] |
MMPF NPs | tumor | 810 | 680 | [107] |
ASO | tumor | 790 | 600 | [111] |
SPN-PT | brain vasculature | 820 | 710 | [125] |
SPN-II | vessels | 1064 | - | [132] |
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Wang, Z.; Han, D.; Wang, H.; Zheng, M.; Xu, Y.; Zhang, H. Organic Semiconducting Nanoparticles for Biosensor: A Review. Biosensors 2023, 13, 494. https://doi.org/10.3390/bios13040494
Wang Z, Han D, Wang H, Zheng M, Xu Y, Zhang H. Organic Semiconducting Nanoparticles for Biosensor: A Review. Biosensors. 2023; 13(4):494. https://doi.org/10.3390/bios13040494
Chicago/Turabian StyleWang, Zheng, Dongyang Han, Hongzhen Wang, Meng Zheng, Yanyi Xu, and Haichang Zhang. 2023. "Organic Semiconducting Nanoparticles for Biosensor: A Review" Biosensors 13, no. 4: 494. https://doi.org/10.3390/bios13040494