Pressure-Free Assembling of Poly(methyl methacrylate) Microdevices via Microwave-Assisted Solvent Bonding and Its Biomedical Applications
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Bonding Mechanism
2.3. Contact Angle Measurement
2.4. Bond Strength Analyses
2.5. Bonded PMMA Microdevice as a Passive Micromixer
2.6. Bonded PMMA Microdevice as a Platform for Human Cell Culture
3. Results and Discussion
3.1. Contact Angle Measurement
3.2. Bonding Performance: Effect of Acetic Acid Concentrations and Addition of Grooves
3.3. Bond Strength Measurement
3.4. Microchannel Profile: Cross-Sectional View of the Microchannel
3.5. Leak Test
3.6. Bonded PMMA Microdevice Used as a Planar Passive Micromixer
3.7. Bonded PMMA Microdevice for Human Cell Culture
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
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Trinh, K.T.L.; Chae, W.R.; Lee, N.Y. Pressure-Free Assembling of Poly(methyl methacrylate) Microdevices via Microwave-Assisted Solvent Bonding and Its Biomedical Applications. Biosensors 2021, 11, 526. https://doi.org/10.3390/bios11120526
Trinh KTL, Chae WR, Lee NY. Pressure-Free Assembling of Poly(methyl methacrylate) Microdevices via Microwave-Assisted Solvent Bonding and Its Biomedical Applications. Biosensors. 2021; 11(12):526. https://doi.org/10.3390/bios11120526
Chicago/Turabian StyleTrinh, Kieu The Loan, Woo Ri Chae, and Nae Yoon Lee. 2021. "Pressure-Free Assembling of Poly(methyl methacrylate) Microdevices via Microwave-Assisted Solvent Bonding and Its Biomedical Applications" Biosensors 11, no. 12: 526. https://doi.org/10.3390/bios11120526