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Article

Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes—Findings from a Large UK Centre

1
Medical School, University of Manchester, Manchester M13 9PL, UK
2
Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK
3
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK
*
Author to whom correspondence should be addressed.
These authors equally contributed to this work.
Biosensors 2021, 11(11), 457; https://doi.org/10.3390/bios11110457
Received: 18 October 2021 / Revised: 7 November 2021 / Accepted: 10 November 2021 / Published: 15 November 2021
(This article belongs to the Special Issue Glucose Sensors—an Essential Tool in Diabetes Management)
Flash glucose monitoring (FGM) and real-time continuous glucose monitoring (RT-CGM) are increasingly used in clinical practice, with improvements in HbA1c and time in range (TIR) reported in clinical studies. We aimed to evaluate the impact of FGM and RT-CGM use on glycaemic outcomes in adults with type 1 diabetes (T1DM) under routine clinical care. We performed a retrospective data analysis from electronic outpatient records and proprietary web-based glucose monitoring platforms. We measured HbA1c (pre-sensor vs. on-sensor data) and sensor-based outcomes from the previous three months as per the international consensus on RT-CGM reporting guidelines. Amongst the 789 adults with T1DM, HbA1c level decreased from 61.0 (54.0, 71.0) mmol/mol to 57 (49, 65.8) mmol/mol in 561 people using FGM, and from 60.0 (50.0, 70.0) mmol/mol to 58.8 (50.3, 66.8) mmol/mol in 198 using RT-CGM (p < 0.001 for both). We found that 23% of FGM users and 32% of RT-CGM users achieved a time-in-range (TIR) (3.9 to 10 mmol/L) of >70%. For time-below-range (TBR) < 4 mmol/L, 70% of RT-CGM users and 58% of FGM users met international recommendations of <4%. Our data add to the growing body of evidence supporting the use of FGM and RT-CGM in T1DM. View Full-Text
Keywords: type 1 diabetes; flash glucose monitoring; continuous glucose monitoring; Freestyle Libre; Dexcom G6 type 1 diabetes; flash glucose monitoring; continuous glucose monitoring; Freestyle Libre; Dexcom G6
MDPI and ACS Style

Lee, K.; Gunasinghe, S.; Chapman, A.; Findlow, L.A.; Hyland, J.; Ohol, S.; Urwin, A.; Rutter, M.K.; Schofield, J.; Thabit, H.; Leelarathna, L. Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes—Findings from a Large UK Centre. Biosensors 2021, 11, 457. https://doi.org/10.3390/bios11110457

AMA Style

Lee K, Gunasinghe S, Chapman A, Findlow LA, Hyland J, Ohol S, Urwin A, Rutter MK, Schofield J, Thabit H, Leelarathna L. Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes—Findings from a Large UK Centre. Biosensors. 2021; 11(11):457. https://doi.org/10.3390/bios11110457

Chicago/Turabian Style

Lee, Kyuhan, Shakthi Gunasinghe, Alyson Chapman, Lynne A. Findlow, Jody Hyland, Sheetal Ohol, Andrea Urwin, Martin K. Rutter, Jonathan Schofield, Hood Thabit, and Lalantha Leelarathna. 2021. "Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes—Findings from a Large UK Centre" Biosensors 11, no. 11: 457. https://doi.org/10.3390/bios11110457

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