Next Article in Journal
Recent Advances in Magnetic Microfluidic Biosensors
Next Article in Special Issue
Three-Dimensional Porous Nitrogen-Doped NiO Nanostructures as Highly Sensitive NO2 Sensors
Previous Article in Journal
Effect of Precursor on Antifouling Efficacy of Vertically-Oriented Graphene Nanosheets
Previous Article in Special Issue
A Large-Area Nanoplasmonic Sensor Fabricated by Rapid Thermal Annealing Treatment for Label-Free and Multi-Point Immunoglobulin Sensing
Open AccessArticle

Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation

1
Centro de Investigación de Procesos Redox, CiPRex, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone 1007, Independencia, Santiago 8380492, Chile
2
Advanced Center for Chronic D (ACCDiS), Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Sergio Livingstone 1007, Independencia, Santiago 8380492, Chile
3
Facultad de Química, Universidad de la República de Uruguay, Avenida General Flores 2124, Montevideo 11800, Uruguay
4
Instituto de Química Física Rocasolano, CSIC, calle Serrano 119, 28006 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Guozhen Liu
Nanomaterials 2017, 7(7), 168; https://doi.org/10.3390/nano7070168
Received: 21 April 2017 / Revised: 27 June 2017 / Accepted: 27 June 2017 / Published: 4 July 2017
(This article belongs to the Special Issue Nanomaterials for Sensing Applications)
For the first time a critical analysis of the influence that four different graphene oxide reduction methods have on the electrochemical properties of the resulting reduced graphene oxides (RGOs) is reported. Starting from the same graphene oxide, chemical (CRGO), hydrothermal (hTRGO), electrochemical (ERGO), and thermal (TRGO) reduced graphene oxide were produced. The materials were fully characterized and the topography and electroactivity of the resulting glassy carbon modified electrodes were also evaluated. An oligonucleotide molecule was used as a model of DNA electrochemical biosensing. The results allow for the conclusion that TRGO produced the RGOs with the best electrochemical performance for oligonucleotide electroanalysis. A clear shift in the guanine oxidation peak potential to lower values (~0.100 V) and an almost two-fold increase in the current intensity were observed compared with the other RGOs. The electrocatalytic effect has a multifactorial explanation because the TRGO was the material that presented a higher polydispersity and lower sheet size, thus exposing a larger quantity of defects to the electrode surface, which produces larger physical and electrochemical areas. View Full-Text
Keywords: graphene; reduced graphene oxide; glassy carbon electrode; SECM; DNA oxidation graphene; reduced graphene oxide; glassy carbon electrode; SECM; DNA oxidation
Show Figures

Graphical abstract

MDPI and ACS Style

Báez, D.F.; Pardo, H.; Laborda, I.; Marco, J.F.; Yáñez, C.; Bollo, S. Reduced Graphene Oxides: Influence of the Reduction Method on the Electrocatalytic Effect towards Nucleic Acid Oxidation. Nanomaterials 2017, 7, 168.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop