Mesoporous Silica Nanoparticles with Co-Condensed Gadolinium Chelates for Multimodal Imaging
Abstract
:1. Introduction
2. Results and Discussion
2.1. Synthesis
2.2. Characterization
Particles | Gd complex in the feed (wt %) | Incorporated Gd complex by TGA | Gd content by DCP | Incorporated Gd complex by DCP |
---|---|---|---|---|
1 | Gd-1 (10) | 16.0 | 5.3 | 15.2 |
2 | Gd-2 (10) | 15.5 | 3.8 | 15.1 |
3 | Gd-2 (20) | 23.1 | 4.7 | 18.7 |
4 | Gd-2 (30) | 27.7 | 6.8 | 26.8 |
5 | Gd-2 (40) | 28.8 | 8.1 | 32 |
Particle | Gd complex in the Feed (wt %) | Surface area (m2/g) | Pore size (nm) |
---|---|---|---|
1 | Gd-1 (10) | 832 | 1.94 |
2 | Gd-2 (10) | 1674 | 2.91 |
3 | Gd-2 (20) | 1095 | 2.75 |
4 | Gd-2 (30) | 923 | 2.46 |
5 | Gd-2 (40) | 149 | 1.41 |
Particles | r1(mM−1s−1) | r2 (mM−1s−1) |
---|---|---|
1 | 6.2 | 32.7 |
2 | 5.1 | 16.1 |
3 | 4.1 | 25.3 |
4 | 4.8 | 22.9 |
5 | 8.4 | 25.6 |
2.3. In Vitro Experiments
3. Experimental Section
4. Conclusions
Supplementary Materials
Supplementary File 1Acknowledgements
References
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Taylor-Pashow, K.M.L.; Rocca, J.D.; Lin, W. Mesoporous Silica Nanoparticles with Co-Condensed Gadolinium Chelates for Multimodal Imaging. Nanomaterials 2012, 2, 1-14. https://doi.org/10.3390/nano2010001
Taylor-Pashow KML, Rocca JD, Lin W. Mesoporous Silica Nanoparticles with Co-Condensed Gadolinium Chelates for Multimodal Imaging. Nanomaterials. 2012; 2(1):1-14. https://doi.org/10.3390/nano2010001
Chicago/Turabian StyleTaylor-Pashow, Kathryn M. L., Joseph Della Rocca, and Wenbin Lin. 2012. "Mesoporous Silica Nanoparticles with Co-Condensed Gadolinium Chelates for Multimodal Imaging" Nanomaterials 2, no. 1: 1-14. https://doi.org/10.3390/nano2010001