Correction: Motamedi et al. Enhancement of Thermostability of Aspergillus flavus Urate Oxidase by Immobilization on the Ni-Based Magnetic Metal–Organic Framework. Nanomaterials 2021, 11, 1759

Text Correction

There was an update made to the original publication [1]. The authors have included information about cytotoxicity data from the literature in Section 1 Introduction, Paragraph 2:

Fe₃O₄–Ni MOF composites were found to exhibit minimal toxicity toward healthy cells, confirming their potential as safe biomedical materials. For example, MIL-100(Fe) was shown to maintain viability ≥85.97% in both normal liver HL-7702 cells, with negligible LDH leakage and apoptotic signs, indicating excellent biocompatibility even at substantial concentrations [40]. Similarly, magnetic Fe₃O₄ nanoparticles—including variants like Fe₃O₄@Au—were categorized as grade 0–1 non-cytotoxic for L-929 fibroblasts, induced virtually no hemolysis (<5%), and exhibited a high LD₅₀ (~8.4 g/kg) in animal models [41]. Also, research has shown that Ni-based MOFs exhibit strong biocompatibility with healthy cells [42,43]. These studies collectively demonstrate that Fe₃O₄–Ni MOF systems and related iron oxide composites cause little to no harm to healthy mammalian cells, reinforcing their suitability for therapeutic and diagnostic applications.

There was an error in the original publication. The manufacturer and model of the SEM instrument have been updated in Section 2. Materials and Methods, 2.4. Characterization of the Synthesized NimMOF, Paragraph 1:

FTIR spectroscopy of synthesized NimMOF and Fe₃O₄ NPs was performed by a Fourier transform spectrometer, Bruker TENSOR 27, Billerica, MA, USA. Moreover, the crystalline structure of NimMOF and Fe₃O₄ NPs was assayed by the XRD technique (Bruker Advance-D8 instrument and CuKα). The SEM method (FEI Quanta 200, Hillsboro, OR, USA) was used for the morphology observation of synthesized NPs, which operated at 25 kV.

Citation and References Correction

In the original publication [1], the following publications were not cited:

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• 41. Chen, D.; Tang, Q.; Li, X.; Zhou, X.; Xue, W.; Zang, J.; Xiang, J.; Guo, C. Biocompatibility of magnetic Fe₃O₄ nanoparticles and their cytotoxic effect on MCF-7 cells. Int. J. Nanomed. 2012, 7, 4973–4982. https://doi.org/10.2147/ijn.s35140.
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These citations have now been inserted in 1: Introduction, Paragraph 2.

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With this correction, the order of some references has been adjusted accordingly.

The authors state that the scientific conclusions are unaffected. The Academic Editor approved this correction. The original publication has also been updated.