Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments
Abstract
:1. Introduction
2. Materials and Methods
2.1. Material Preparation
2.2. Fabrication Method
2.3. Characterization of Radial Stiffness
2.4. Compression Test Simulation
2.5. Optimal Design of Stents
3. Results and Discussion
3.1. Biodegradable Polymeric Stents Fabricated by DBRP Technique
3.1.1. Coil Structure with Different Concentration of PCL Solution
3.1.2. Zigzag Structure with Different Concentration of PCL Solution
3.1.3. Zigzag Structure Made of 70% PCL Solution
3.2. Characterization of Biodegradable Polymeric Stents for Coil and Zigzag Structures
3.3. Comparison between Real Compression Test and Simulation
3.4. Optimization of Biodegradable Polymeric Stents
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Label | Concentration | Speed of Dispensing Head |
---|---|---|
A | 70% | 0.85 |
B | 70% | 0.7 |
C | 70% | 0.9 |
D | 70% | 1.1 |
E | 70% | 1.3 |
F | 60% | 0.7 |
G | 50% | 0.7 |
Coil A | 50% | 0.7 |
Coil B | 70% | 0.7 |
Label | Concentration of PCL Solution | Diameter of the Needle (mm) | Samples |
---|---|---|---|
Coil 50 | 50% PCL | 0.25 | |
Coil 60 | 60% PCL | 0.41 | |
Coil 70 | 70% PCL | 0.41 |
Label | Concentration of PCL solution | Diameter of the Needle (mm) | Samples |
---|---|---|---|
Zigzag 50 | 50% PCL | 0.25 | |
Zigzag 60 | 60% PCL | 0.41 | |
Zigzag 70 | 70% PCL | 0.41 |
Label | Dispensing Speed (Inch/s) | Samples |
---|---|---|
Zigzag 70-0.7 | 0.7 | |
Zigzag 70-0.85 | 0.85 | |
Zigzag 70-0.9 | 0.9 | |
Zigzag 70-1.1 | 1.1 | |
Zigzag 70-1.3 | 1.3 |
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Han, X.; Wu, X.; Kelly, M.; Chen, X. Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments. J. Funct. Biomater. 2017, 8, 8. https://doi.org/10.3390/jfb8010008
Han X, Wu X, Kelly M, Chen X. Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments. Journal of Functional Biomaterials. 2017; 8(1):8. https://doi.org/10.3390/jfb8010008
Chicago/Turabian StyleHan, Xue, Xia Wu, Michael Kelly, and Xiongbiao Chen. 2017. "Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments" Journal of Functional Biomaterials 8, no. 1: 8. https://doi.org/10.3390/jfb8010008