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Open AccessArticle

Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride

Departamento de Química Física II, Facultad de Farmacia, UCM, 28040 Madrid, Spain
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J. Funct. Biomater. 2011, 2(2), 31-38; https://doi.org/10.3390/jfb2020031
Received: 8 April 2011 / Revised: 16 May 2011 / Accepted: 30 May 2011 / Published: 31 May 2011
The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis. View Full-Text
Keywords: Brushite; calcium phosphate cement; strontium; glycolic acid Brushite; calcium phosphate cement; strontium; glycolic acid
MDPI and ACS Style

Alkhraisat, M.H.; Rueda, C.; López Cabarcos, E. Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride. J. Funct. Biomater. 2011, 2, 31-38.

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