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Article

Adhesion and Colonization Intensity of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on Smooth, Micro-Textured, and Macro-Textured Silicone Biomaterials

by
Kirils Jurševičs
1,*,
Ingus Skadiņš
2,
Jeļena Krasiļņikova
3,
Anna Lece
4,
Andrejs Šķesters
4 and
Eduards Jurševičs
5
1
Department of Doctoral Studies, Riga Stradiņš University, LV1007 Riga, Latvia
2
Department of Biology and Microbiology, Riga Stradiņš University, LV1007 Riga, Latvia
3
Department of Human Physiology and Biochemistry, Riga Stradiņš University, LV1007 Riga, Latvia
4
Scientific Laboratory of Biochemistry, Riga Stradiņš University, LV1067 Riga, Latvia
5
Clinic of Aesthetic Medicine of Medical Doctor Edward Yurshevich, LV1010 Riga, Latvia
*
Author to whom correspondence should be addressed.
J. Funct. Biomater. 2025, 16(9), 322; https://doi.org/10.3390/jfb16090322
Submission received: 5 August 2025 / Revised: 27 August 2025 / Accepted: 30 August 2025 / Published: 1 September 2025
(This article belongs to the Section Antibacterial Biomaterials)
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Abstract

Implantable biomaterials are widely used in modern medicine, especially in orthopaedics, cardiovascular surgery, dentistry, and plastic and reconstructive surgery. The issue of the interaction of implants with body tissues and the risk of infection associated with them is one of the most studied and topical issues in medicine. It is very important to find a biomaterial that effectively combines both microbiology and tissue compatibility aspects. The aim of this research work was to determine the adhesion and colonization rates of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on smooth, microtextured, and macro-textured silicone biomaterials in an in vitro study. A total of 90 silicone biomaterial samples were used, 30 for each type of biomaterial. In each of the biomaterial groups, half of the samples (n = 15) were used to determine the adhesion intensity and the other half to determine the colonization intensity on the active surface of the biomaterial samples. The study found that Staphylococcus epidermidis and Pseudomonas aeruginosa had the highest adhesion intensity on the macro-textured implant, while Candida albicans adhered best to smooth. Among the microorganisms, Pseudomonas aeruginosa demonstrated the highest colonization rate, followed by Staphylococcus epidermidis and then Candida albicans. The most intensive colonization of microorganisms was on the macro-textured implant, then on the micro-textured, and then on the smooth. The smooth and micro-textured implants did not show statistically significant differences in the intensity of adhesion and colonization. The biomaterials did not show pro-oxidant or anti-oxidant properties, and no lipid peroxidation was induced by the biomaterials.
Keywords: silicone implant; biomaterial; adhesion; colonization; Staphylococcus epidermidis; Pseudomonas aeruginosa; Candida albicans silicone implant; biomaterial; adhesion; colonization; Staphylococcus epidermidis; Pseudomonas aeruginosa; Candida albicans

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MDPI and ACS Style

Jurševičs, K.; Skadiņš, I.; Krasiļņikova, J.; Lece, A.; Šķesters, A.; Jurševičs, E. Adhesion and Colonization Intensity of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on Smooth, Micro-Textured, and Macro-Textured Silicone Biomaterials. J. Funct. Biomater. 2025, 16, 322. https://doi.org/10.3390/jfb16090322

AMA Style

Jurševičs K, Skadiņš I, Krasiļņikova J, Lece A, Šķesters A, Jurševičs E. Adhesion and Colonization Intensity of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on Smooth, Micro-Textured, and Macro-Textured Silicone Biomaterials. Journal of Functional Biomaterials. 2025; 16(9):322. https://doi.org/10.3390/jfb16090322

Chicago/Turabian Style

Jurševičs, Kirils, Ingus Skadiņš, Jeļena Krasiļņikova, Anna Lece, Andrejs Šķesters, and Eduards Jurševičs. 2025. "Adhesion and Colonization Intensity of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on Smooth, Micro-Textured, and Macro-Textured Silicone Biomaterials" Journal of Functional Biomaterials 16, no. 9: 322. https://doi.org/10.3390/jfb16090322

APA Style

Jurševičs, K., Skadiņš, I., Krasiļņikova, J., Lece, A., Šķesters, A., & Jurševičs, E. (2025). Adhesion and Colonization Intensity of Staphylococcus epidermidis, Pseudomonas aeruginosa, and Candida albicans on Smooth, Micro-Textured, and Macro-Textured Silicone Biomaterials. Journal of Functional Biomaterials, 16(9), 322. https://doi.org/10.3390/jfb16090322

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