Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial
Abstract
1. Introduction
2. Experimental Section
2.1. Patients
2.2. Anesthesia
2.3. SRS
2.4. Abdominal Wall Length
2.5. Statistics
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Variables: | Age (years) | Height (cm) | Weight (kg) | BMI (kg/cm2) | Rocuronium (mg) Initial Dose | Rocuronium (mg) Repetition |
---|---|---|---|---|---|---|
Mean (SD) | 50.9 (13.4) | 167.4 (5.4) | 70.8 (13.9) | 25.2 (4.5) | 37.4 (3.8) | 17.9 (7.2) |
Drugs | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% |
---|---|---|---|---|---|
Propofol infusion: mg kg h−1 (mean (SD)) | 3.7 (0.7) | 3.8 (0.8) | 3.6 (0.8) | 3.8 (1.0) | 3.8 (0.9) |
Remifentanil infusion: µg kg min−1 (mean (SD)) | 0.12 (0.03) | 0.13 (0.03) | 0.13 (0.03) | 0.14 (0.03) | 0.14 (0.04) |
Sufentanil bolus: number | 12 | 14 | 3 | 12 | 3 |
Sufentanil bolus: mg (mean (SD)) | 15.0 (7.1) | 11.1 (5.6) | 13.3 (5.8) | 10.0 (4.3) | 8.3 (2.9) |
Rocuronium bolus: number | 0 | 0 | 5 | 1 | 0 |
Rocuronium bolus: mg (mean (SD)) | - | - | 13 (4.5) | 10 | - |
Variables: | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
BIS | 41.6 (5.5) | 41.9 (6.3) | 41.3 (5.0) | 42.8 (5.5) | 43.5 (4.6) | n.s. |
BP syst (mm Hg) | 96.8 (18.2) | 105.6 (21.1) | 110.1 (18.0) * | 109.4 (16.6) * | 102.4 (15.7) | *: p < 0.001 vs. PTC = 0 |
BP diast (mm Hg) | 56.6 (11.7) | 63.4 (13.7) * | 67.8 (10.1) * + | 65.6 (10.2) * + | 60.0 (7.7) | *: p < 0.001 vs. PTC = 0 +: p <0.008 vs. TOFR > 90% |
HR | 56.1 (8.9) | 56.9 (8.1) | 58.3 (9.6) # | 57.4 (8.8) | 55.9 (8.8) | #: p < 0.05 vs. TOFR > 90% |
Abdominal Wall Length | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
Increase in mm: mean (SD) | 11.5 (4.6) | 11.5 (4.9) | 10.5 (4.5) | 11.1 (5.9) | 10.6 (5.2) | 0.17 |
SRS | PTC = 0 | PTC = 1–5 | TOF 0–1 | TOF > 1 | TOFR > 90% | p-Value |
---|---|---|---|---|---|---|
SRS (mean (SD)) | 4.7 (0.5) | 4.6 (0.5) | 4.6 (0.5) | 4.6 (0.6) | 4.5 (0.5) * | *: p = 0.025 vs. PTC = 0 |
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Soltesz, S.; Mathes, A.; Anapolski, M.; Noé, K.G. Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial. J. Clin. Med. 2020, 9, 1078. https://doi.org/10.3390/jcm9041078
Soltesz S, Mathes A, Anapolski M, Noé KG. Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial. Journal of Clinical Medicine. 2020; 9(4):1078. https://doi.org/10.3390/jcm9041078
Chicago/Turabian StyleSoltesz, Stefan, Alexander Mathes, Michael Anapolski, and Karl Guenter Noé. 2020. "Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial" Journal of Clinical Medicine 9, no. 4: 1078. https://doi.org/10.3390/jcm9041078
APA StyleSoltesz, S., Mathes, A., Anapolski, M., & Noé, K. G. (2020). Depth of Neuromuscular Block Is Not Associated with Abdominal Wall Distention or Surgical Conditions during Gynecologic Laparoscopic Operations. A Prospective Trial. Journal of Clinical Medicine, 9(4), 1078. https://doi.org/10.3390/jcm9041078