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J. Clin. Med. 2019, 8(2), 237; https://doi.org/10.3390/jcm8020237

Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms

1
Faculty of Medicine, Jagiellonian University Medical College, 31-008 Kraków, Poland
2
Faculty of Computer Science, Electronics and Telecommunications, AGH University of Science and Technology, 30-059 Kraków, Poland
3
TENSOR—Team of NeuroSurgery-Oriented Reaserch, Jagiellonian University Medical College, 31-008 Kraków, Poland
4
Department of Neurosurgery and Neurotraumatology, Jagiellonian University Medical College, 31-503 Kraków, Poland
5
Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, 31-531 Kraków, Poland
*
Author to whom correspondence should be addressed.
Received: 26 December 2018 / Revised: 16 January 2019 / Accepted: 1 February 2019 / Published: 12 February 2019
(This article belongs to the Section Vascular Medicine)
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Abstract

Tortuosity of blood vessels is a common angiographic finding that may indicate systemic disease and can be correlated with vascular pathologies. In this work, we determined whether patients with and without internal carotid artery (ICA) aneurysm presented with differences in its tortuosity descriptors. We retrospectively analysed data of 298 patients hospitalized between January 2014 and June 2018. For each patient’s imaging data, we extracted a curve representing the ICA course and measured its Relative Length (RL), Sum of Angle Metrics (SOAM), Product of Angle Distance (PAD), Triangular Index (TI), and Inflection Count Metrics (ICM). We found that patients with an ICA aneurysm had significantly lower RL (0.46 ± 0.19 vs. 0.51 ± 0.17; p = 0.023) and significantly higher SOAM (0.39 ± 0.21 vs. 0.32 ± 0.21 p = 0.003), PAD (0.38 ± 0.19 vs. 0.32 ± 0.21; p = 0.011), TI (0.30 ± 0.11 vs. 0.27 ± 0.14; p = 0.034), and ICM (0.30 ± 0.16 vs. 0.22 ± 0.12; p < 0.001). We found that that patients who presented with a subarachnoid hemorrhage had significantly higher PAD (0.46 ± 0.22 vs. 0.35 ± 0.20; p = 0.024). In conclusion, higher tortuosity of ICA is associated with ICA aneurysm presence. View Full-Text
Keywords: intracranial aneurysm; tortuosity; internal carotid artery intracranial aneurysm; tortuosity; internal carotid artery
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Kliś, K.M.; Krzyżewski, R.M.; Kwinta, B.M.; Stachura, K.; Gąsowski, J. Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms. J. Clin. Med. 2019, 8, 237.

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