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J. Clin. Med. 2019, 8(2), 214; https://doi.org/10.3390/jcm8020214

Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam

1
Department of Internal Medicine, Hanoi Medical University, Hanoi 100000, Vietnam
2
Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam
3
Center of Excellence in Evidence-based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam
4
Institute for Global Health Innovations, Duy Tan University, Da Nang 550000, Vietnam
5
Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam
6
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
7
Department of Psychological Medicine, National University Hospital, Singapore 119074, Singapore
8
Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore
*
Author to whom correspondence should be addressed.
Received: 6 November 2018 / Revised: 31 January 2019 / Accepted: 5 February 2019 / Published: 7 February 2019
(This article belongs to the Section Pulmonology)
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Abstract

Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with different comorbidities in a Vietnamese tertiary hospital. We performed a cross-sectional study from October to November 2016 at the Respiratory Center of Bach Mai Hospital, Hanoi, with a total of 508 participants. Information about socio-economic characteristics, HRQOL and comorbidities of participants was collected. ANOVA was used to identify MCID between patients with and without specific comorbid conditions. Tobit regression was used to explore the associations between comorbidities and the HRQOL. Results showed that the prevalence of cardiovascular comorbidities was 23.8%, followed by musculoskeletal diseases (12.0%), digestive diseases (11.8%), endocrine diseases (10.0%), kidney diseases (5.1%) and ear, nose, and throat diseases (4.5%). Regarding HRQOL, having a problem in pain/discomfort was observed in 61.0% of participants, followed by anxiety/depression (48.2%). Mean EQ-5D index was 0.66 (SD (Standard Deviation) = 0.31). The significant MCID (p < 0.05) was found between patients with and without cardiovascular diseases, musculoskeletal diseases, kidney diseases, and endocrine diseases. The multivariate regression model showed that only musculoskeletal diseases were found to be related with the marked decrement of EQ-5D index score (Coef. = −0.13; 95% CI (Confident Interval) = −0.23; −0.02). Suffering at least one chronic illness was correlated to the marked decrease of EQ-5D index score (Coef. = −0.09; 95% CI = −0.17; −0.01). These results underline the importance of appropriate pain management as well as the provision of an interprofessional care approach to patients in order to alleviate the burden of comorbidities to their treatment outcomes and HRQOL. View Full-Text
Keywords: respiratory diseases; comorbidity; HRQOL; minimally clinically important difference; Vietnam respiratory diseases; comorbidity; HRQOL; minimally clinically important difference; Vietnam
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Ngo, C.Q.; Phan, P.T.; Vu, G.V.; Pham, Q.L.T.; Nguyen, L.H.; Vu, G.T.; Tran, T.T.; Nguyen, H.L.T.; Tran, B.X.; Latkin, C.A.; Ho, C.S.H.; Ho, R.C.M. Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam. J. Clin. Med. 2019, 8, 214.

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