Next Article in Journal
Complementary Medicine: Risks to Infants and Children
Next Article in Special Issue
A Review of HPV-Related Head and Neck Cancer
Previous Article in Journal
Randomized Controlled Trial Considering Varied Exercises for Reducing Proactive Memory Interference
Previous Article in Special Issue
The Role of Diffusion-Weighted Magnetic Resonance Imaging in the Differentiation of Head and Neck Masses
Open AccessReview

The Role of Procalcitonin in the Diagnosis of Meningitis: A Literature Review

1
Department of Medicine, University of Patras, 26504 Patras, Greece
2
University of Medicine and Pharmacy, 400337 Cluj-Napoca, România
3
School of Medicine University of Patras, 26500 Patras, Greece
4
Intensive Care Unit, University Hospital of Patras, Rion 26500, Greece
5
Intensive Care Department, Brugmann University Hospital, 1020 Brussels, Belgium
6
Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63144, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(6), 148; https://doi.org/10.3390/jcm7060148
Received: 4 June 2018 / Accepted: 8 June 2018 / Published: 11 June 2018
Objective: To review the current published literature on the use of procalcitonin as a diagnostic and prognostic marker in adult patients with meningitis. Methods: We conducted a PubMed search to identify all relevant publications regarding the diagnostic and prognostic value of serum procalcitonin in patients with a known or suspected central nervous system infection. We also reviewed the bibliographies of all identified manuscripts in an attempt to identify additional relevant references. Results: A significant body of evidence suggests that serum procalcitonin has a promising role and can be a useful biomarker in the assessment of patients with meningitis. Conclusions: Our literature review suggests that data on the role of Cerebrospinal Fluid (CSF) procalcitonin are limited, whereas serum procalcitonin (S–PCT) is probably a useful tool in the evaluation of patients with a known or suspected central nervous system infection and can help distinguish between bacterial and viral meningitis. View Full-Text
Keywords: procalcitonin; bacterial meningitis; viral meningitis; antibiotic therapy; biomarker; differential diagnosis procalcitonin; bacterial meningitis; viral meningitis; antibiotic therapy; biomarker; differential diagnosis
Show Figures

Figure 1

MDPI and ACS Style

Velissaris, D.; Pintea, M.; Pantzaris, N.; Spatha, E.; Karamouzos, V.; Pierrakos, C.; Karanikolas, M. The Role of Procalcitonin in the Diagnosis of Meningitis: A Literature Review. J. Clin. Med. 2018, 7, 148.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop