Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Unilateral (n = 87) | Bilateral (n = 27) | p-Value | |
---|---|---|---|
Age [years], mean (SD) | 51 (9.3) | 48 (7.7) | 0.11 |
BMI [kg/m2] (SD) | 26 (4.3) | 28 (4.2) | 0.22 |
Smoker, n (%) | 21 (24%) | 7 (26%) | 0.76 |
Hypertension, n (%) | 14 (16%) | 3 (11%) | 0.76 |
Diabetes, n (%) | 1 (1.1%) | 0 (0%) | >0.99 |
Abdominal Scar, n (%) | 46 (53%) | 12 (44%) | 0.59 |
Radiotherapy, n (%) | 30 (34%) | 15 (56%) | 0.083 |
Chemotherapy, n (%) | 41 (47%) | 23 (85%) | 0.0011 |
Hormone Therapy, n (%) | 48 (55%) | 14 (52%) | 0.94 |
Follow-up [months], mean (SD) | 17 (15) | 18 (14) | 0.64 |
Unilateral (n = 87) | Bilateral (n = 27) | p-Value | |
---|---|---|---|
Primary reconstruction, n (%) | 11 (13%) | 7 (26%) | 0.13 |
Secondary reconstruction, n (%) | 76 (87%) | 20 (74%) | 0.13 |
Curative, n (%) | 83 (95%) | 11 (41%) | <0.0001 |
Prophylactic, n (%) | 4 (4.6%) | 16 (59%) | <0.0001 |
Mean operation time [minutes], mean (SD) | 460 (85) | 650 (160) | <0.0001 |
Mean ischemia time (SD) [minutes], per breast | 95 (33) | 92 (34) | 0.69 |
Unilateral (n = 87) | Bilateral (n = 54) | p-Value | |
---|---|---|---|
Breast recipient site | |||
≥1 complication, n (%) | 16 (18%) | 9 (17%) | 0.79 |
Seroma, n (%) | 1 (1.1%) | 0 (0%) | >0.99 |
Hematoma, n (%) | 4 (4.6%) | 2 (3.7%) | >0.99 |
Wound infection, n (%) | 1 (1.1%) | 1 (1.9%) | >0.99 |
Wound dehiscence, n (%) | 4 (4.6%) | 1 (1.9%) | 0.65 |
Delayed wound healing, n (%) | 4 (4.6%) | 1 (1.9%) | 0.65 |
Partial NAC necrosis, n (%) | 1 (1.1%) | 1 (1.9%) | >0.99 |
DIEP flap | |||
Venous congestion, n (%) | 1 (1.1%) | 1 (1.9%) | >0.99 |
Venous thrombosis, n (%) | 1 (1.1%) | 0 (0%) | >0.99 |
Arterial thrombosis, n (%) | 1 (1.1%) | 1 (1.9%) | >0.99 |
Total flap loss, n (%) | 1 (1.1%) | 1 (1.9%) | >0.99 |
Partial flap loss, n (%) | 1 (1.1%) | 2 (3.7%) | >0.99 |
Unilateral (n = 87) | Bilateral (n = 27) | p-Value | |
---|---|---|---|
≥1 complication, n (%) | 29 (33%) | 11 (50%) | 0.48 |
Seroma, n (%) | 6 (6.9%) | 0 (0%) | 0.33 |
Hematoma, n (%) | 3 (3.4%) | 1 (3.7%) | >0.99 |
Wound infection, n (%) | 1 (1.1%) | 1 (3.7%) | 0.42 |
Wound dehiscence, n (%) | 7 (8.0%) | 3 (11%) | 0.70 |
Delayed wound healing, n (%) | 8 (9.2%) | 4 (15%) | 0.47 |
Hypertrophic scar, n (%) | 2 (2.3%) | 1 (3.7%) | 0.56 |
Dog-ear scar deformity, n (%) | 3 (3.4%) | 2 (7.4%) | 0.59 |
Incisionial hernia, n (%) | 1 (1.1%) | 0 (0%) | >0.99 |
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Tekdogan, B.; Martineau, J.; Verbat, M.; Dong, E.T.C.; Correia, D.; Oranges, C.M. Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study. J. Clin. Med. 2025, 14, 1056. https://doi.org/10.3390/jcm14041056
Tekdogan B, Martineau J, Verbat M, Dong ETC, Correia D, Oranges CM. Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study. Journal of Clinical Medicine. 2025; 14(4):1056. https://doi.org/10.3390/jcm14041056
Chicago/Turabian StyleTekdogan, Boran, Jérôme Martineau, Miroslava Verbat, Edward T. C. Dong, Daniel Correia, and Carlo M. Oranges. 2025. "Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study" Journal of Clinical Medicine 14, no. 4: 1056. https://doi.org/10.3390/jcm14041056
APA StyleTekdogan, B., Martineau, J., Verbat, M., Dong, E. T. C., Correia, D., & Oranges, C. M. (2025). Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study. Journal of Clinical Medicine, 14(4), 1056. https://doi.org/10.3390/jcm14041056