Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy
Abstract
1. Introduction
2. Materials and Methods
2.1. Search Strategy
2.2. Eligibility Criteria
2.3. Data Acquisition and Risk of Bias
2.4. Data Synthesis and Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
POP | Pelvic organ prolapse |
LS | laparoscopic sacrocolpopexy |
LP | Laparoscopic pectopexy |
PROs | patient-reported outcomes |
QoL | quality of life |
FSFI | Female Sexual Function Index |
P-QOL | Prolapse Quality of Life |
PFDI-20 | Pelvic Floor Distress Inventory |
PFIQ-7 | Pelvic Floor Impact Questionnaire |
PISQ-12 | Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire |
PGI-I | Patient Global Impression of Improvement |
ISI | Incontinence Severity Index |
ICIQ-SF | International Consultation on Incontinence Questionnaire—Short Form |
UDI-6 | Urogenital Distress Inventory |
IIQ-7 | Incontinence Impact Questionnaire |
EPIQ | Epidemiology of Prolapse and Incontinence Questionnaire |
I-QOL | Incontinence Quality of Life |
PISQ-IR | Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire IUGA-Revised |
POPDI-6 | Pelvic organ Prolapse Distress Inverntory-6 |
UI | Urinary incontinence |
IUGA | International Urogynecological Association |
RCTs | Randomized controlled trials |
SSHP | Sacrospinous ligament hysteropexy |
SSLF | Sacrospinous ligament fixation |
References
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Study (Author, Year) | Design | Sample Size (n) | Mean Follow-Up | PROMs Used | Main Findings | Overall Quality Assessment |
---|---|---|---|---|---|---|
Erdem et al., 2022 [8] | Cross-sectional | 35 | 28.9 ± 5.9 months | FSFI, P-QOL | Significant improvement in all FSFI and P-QOL domains (p < 0.001) (Within-group comparison) | High quality |
Peng et al., 2023 [9] | Retrospective cohort | 78 | 12 months | PFDI-20, PFIQ-7, PISQ-12 | Significantly improved postoperative (p < 0.05) The PISQ-12 scores in laparoscopic uterine pectopexy group were significantly higher than that in the other two groups (p < 0.05) (Between-group comparison) | High quality |
Astepe et al., 2019 [10] | Comparative cohort | 36 (LP) | 13.1 months | PISQ-12, P-QOL | Significantly improved postoperative LP had better PISQ-12 scores compared to SSF (38.21 ± 5.69 vs. 36.86 ± 3.15) but similar P-QOL scores (Between-group comparison) | High quality |
Obut et al., 2021 [11] | Prospective randomized | 32 (LP) | 12 months | FSFI, P-QOL | Significant improvement in all FSFI and P-QOL domains in both LP and laparoscopic sacrohysteropexy groups (p < 0.001) (Within-group and Between-group comparison) | High quality |
Khoiwal et al., 2022 [12] | RCT | 15 (LP) | 6 months | PGI-I, P-QOL, PISQ-12 | Significant improvement in all domains in LP and LS groups PGI-I (p = 0.006 vs. 0.009) PISQ-12 (p < 0.001 in both groups) P-QOL(p < 0.001 in both groups)—no difference between the two groups (Within-group and Between-group comparison) | High quality |
Karslı et al., 2021 [13] | Prospective | 31 | 3 months | P-QOL, PISQ-12, UDI-6, IIQ-7 | Significant improvement in all domains (p =0.001) (Within-group comparison) | High quality |
Tahaoglu et al., 2017 [14] | Observational | 22 | 10.4 months | FSFI, P-QOL | Significant improvement in all FSFI and P-QOL domains (p < 0.05) (Within-group comparison) | High quality |
Yu et al., 2023 [15] | Prospective | 49 | 15 months | PFDI-20, PFIQ-7 | Significant improvement in all FSFI and P-QOL domains (p < 0.001) (Within-group comparison) | High quality |
Szymczak et al., 2022 [16] | Prospective observational | 53 | 26.9 ± 12 months | PGI-I, ISI, EPIQ #35, PFIQ-7, PFDI-20 | PGI-I: postoperative improvement in 75.5% of the LP patients and 44 (72.1%) SSLF patients. Improvement in PFDI-20 and PFIQ-7 (p < 0.04) EPIQ #35 was significantly reduced (p < 0.001) ISI: no postoperative deterioration of UI symptoms (Within-group comparison) All scores did not differ between the LP and SSLF/SSHP groups. (Between-group comparison) | High quality |
Chao et al., 2022 [17] | Retrospective cohort | 30 (LP) | 12 months | UDI-6, ICIQ-SF, POPDI-6, PISQ-IR | UDI-6, ICIQ-SF, and POPDI-6 improved significantly (Within-group comparison) No significant differences in the mean difference in postoperative and preoperative UDI-6 (p = 0.834), ICIQ-SF (p = 0.861), POPDI-6 (p = 0.775) scores between LP and LS groups. No significant differences in the mean difference in postoperative and preoperative PISQ-IR question 9 (p = 0.351), PISQ-IR question 11 (p = 0.715), PISQ-IR question 18 (p = 0.192), or PISQ-IR question 19a (p = 0.106) between the two groups. (Between-group comparison) | High quality |
Yang et al., 2023 [18] | Prospective cohort | 102 (LP) | 12 months | PFDI-20, I-QOL | PFDI-20, I-QOL scores had improved significantly LP group showed a greater percent decrease in PFDI-20 and greater percent increase in I-QOL from baseline compared to LS group (Between-group comparison) | High quality |
Vo et al., 2023 [19] | Retrospective case series | 58 | 6 months | PFDI-20, PFIQ-7 | PFDI-20 from 130 → 8 and PFIQ-7 score 148 → 10 at 3 months; 0 at 6 months for both scores (Within-group comparison) | Moderate quality |
Dubinskaya et al., 2022 [20] | Prospective | 22 | 12 months | ICIQ-UI-SF, ICIQ-V, PGI-I | All scores improved significantly (p < 0.001) (Within-group comparison) | High quality |
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Pitsillidi, A.; Grigoriadis, G.; Vona, L.; Noé, G.; Daniilidis, A. Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy. J. Clin. Med. 2025, 14, 6318. https://doi.org/10.3390/jcm14176318
Pitsillidi A, Grigoriadis G, Vona L, Noé G, Daniilidis A. Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy. Journal of Clinical Medicine. 2025; 14(17):6318. https://doi.org/10.3390/jcm14176318
Chicago/Turabian StylePitsillidi, Anna, Georgios Grigoriadis, Laura Vona, Guenter Noé, and Angelos Daniilidis. 2025. "Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy" Journal of Clinical Medicine 14, no. 17: 6318. https://doi.org/10.3390/jcm14176318
APA StylePitsillidi, A., Grigoriadis, G., Vona, L., Noé, G., & Daniilidis, A. (2025). Patient-Reported Outcomes and Quality of Life After Laparoscopic Pectopexy. Journal of Clinical Medicine, 14(17), 6318. https://doi.org/10.3390/jcm14176318