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Volume 14
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Clinical Outcomes of Patients with Achalasia Following Pneumatic Dilation Treatment: A Single Center Experience

by
Viktorija Sabljić
1,
Dorotea Božić
2,*,
Damir Aličić
2,
Žarko Ardalić
2,
Ivna Olić
2,
Damir Bonacin
2,3 and
Ivan Žaja
2,4
1
Institute of Emergency Medicine of Šibenik-Knin County, Narodnog Preporoda 1, 22000 Šibenik, Croatia
2
Department of Gastroenterology and Hepatology, University Hospital Split, Spinčićeva 1, 21000 Split, Croatia
3
School of Medicine, University of Split, Šoltanska 2A, 21000 Split, Croatia
4
Department of Health Studies, University of Split, Ruđera Boškovića 35, 21000 Split, Croatia
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2025, 14(15), 5448; https://doi.org/10.3390/jcm14155448 (registering DOI)
Submission received: 11 June 2025 / Revised: 27 July 2025 / Accepted: 31 July 2025 / Published: 2 August 2025
(This article belongs to the Special Issue Clinical Advances in Gastrointestinal Endoscopy)
Versions Notes

Abstract

Background/Objectives: Pneumatic dilation (PD) is a widely used treatment modality in the management of achalasia. It is particularly relevant in regions where many centers lack access to advanced therapeutic modalities. Therefore, we aimed to assess the effectiveness and safety of PD in our local region. Methods: This study retrospectively analyzed patients with achalasia that underwent PD from 1/2013 to 12/2019. The diagnosis of achalasia was established on the grounds of clinical symptoms, radiological and endoscopic findings, and esophageal manometry. Data on patient’s clinical characteristics, dilation technique and postprocedural follow-up were collected and statistically analyzed. Procedure effectiveness was defined as the postprocedural Eckardt score ≤ 3. Results: PD significantly reduced frequency of dysphagia, regurgitation, and retrosternal pain (p < 0.001). Body-weight increased significantly one month and one year after the procedure (p < 0.001). The procedural success rate was 100%. No severe complications were reported. Conclusions: PD is an effective and safe treatment modality in the management of achalasia. The study limitations include a single center design with the small number of participants, not all of whom underwent manometry, gender disproportion, absence of non-responders, and a short follow-up.
Keywords: pneumatic dilation; achalasia; dysphagia pneumatic dilation; achalasia; dysphagia

Share and Cite

MDPI and ACS Style

Sabljić, V.; Božić, D.; Aličić, D.; Ardalić, Ž.; Olić, I.; Bonacin, D.; Žaja, I. Clinical Outcomes of Patients with Achalasia Following Pneumatic Dilation Treatment: A Single Center Experience. J. Clin. Med. 2025, 14, 5448. https://doi.org/10.3390/jcm14155448

AMA Style

Sabljić V, Božić D, Aličić D, Ardalić Ž, Olić I, Bonacin D, Žaja I. Clinical Outcomes of Patients with Achalasia Following Pneumatic Dilation Treatment: A Single Center Experience. Journal of Clinical Medicine. 2025; 14(15):5448. https://doi.org/10.3390/jcm14155448

Chicago/Turabian Style

Sabljić, Viktorija, Dorotea Božić, Damir Aličić, Žarko Ardalić, Ivna Olić, Damir Bonacin, and Ivan Žaja. 2025. "Clinical Outcomes of Patients with Achalasia Following Pneumatic Dilation Treatment: A Single Center Experience" Journal of Clinical Medicine 14, no. 15: 5448. https://doi.org/10.3390/jcm14155448

APA Style

Sabljić, V., Božić, D., Aličić, D., Ardalić, Ž., Olić, I., Bonacin, D., & Žaja, I. (2025). Clinical Outcomes of Patients with Achalasia Following Pneumatic Dilation Treatment: A Single Center Experience. Journal of Clinical Medicine, 14(15), 5448. https://doi.org/10.3390/jcm14155448

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