Diagnostic Accuracy of Ultrasound Guided Percutaneous Pleural Needle Biopsy for Malignant Pleural Mesothelioma
Abstract
:1. Introduction
2. Methods
2.1. Patients
2.2. US-PPNB: Description of Procedure
2.3. Assessment of Samples
2.4. Statistical Analysis
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Rib fractures |
AMS |
Uncontrolled cardiac arrythmia |
PNT |
Severe anemia |
Chronic heart failure (FE < 40%) |
Severe respiratory failure (P/F ratio < 250) |
INR > 1.5 |
Total number of patients | 18 |
Males | 11 (61%) |
Median age (sd) | 71.2 (±6.61) |
Mean ECOG-PS | 1.55 |
TNM | |
| 3 (16%) |
| 15 (84%) |
Reported exposure to asbestos | 11 (61%) |
Mean pleural lesion thickness (sd) | 13.5 mm (±9.45) |
Mean SUVmax (sd) | 10.7 (±1.58) |
Pleural effusion | 11 (61%) |
Comorbidity | |
Arterial hypertension | 16 (88.8%) |
Chronic renal failure | 5 (27.8%) |
COPD | 7 (38.9%) |
Chronic respiratory failure | 7 (38.9%) |
Pregress stroke | 3 (16.7%) |
Chronic ischemic disease | 4 (22.2%) |
Diabetes | 3 (16.7%) |
Prostatic hypertofic disease | 6 (33.3%) |
Mean number of samples (sd) | 2 (±0.9) |
Accuracy | |
Adequate biopsies | 15 (83%) |
Not-adequate biopsies | 3 (17%) |
Histology | |
Epithelioid | 13 (72%) |
Sarcomatoid | 3 (17%) |
Bifasic | 2 (11%) |
Adequate biopsies | |
Epithelioid | 12 (72%) |
Sarcomatoid | 1 (5%) |
Bifasic | 2 (11%) |
Not-adequate biopsies | |
Epithelioid | 1 (5%) |
Sarcomatoid | 2 (11%) |
Bifasic | 0 (0%) |
Pleural lesion thickness | |
Adequate biopsies | 15.4 mm (±9.19) |
Not-adequate biopsies | 3.77 mm (±0.60) |
Pain assessment | |
NRS < 5 | 14 (78%) |
NRS > 5 | 4 (22%) |
Complications | |
PNT | 4 (22%) |
Hemorrhagic complication | 0 (0%) |
DOP | 21 min (±4.67) |
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Iadevaia, C.; D’Agnano, V.; Pagliaro, R.; Nappi, F.; Lucci, R.; Massa, S.; Bianco, A.; Perrotta, F. Diagnostic Accuracy of Ultrasound Guided Percutaneous Pleural Needle Biopsy for Malignant Pleural Mesothelioma. J. Clin. Med. 2024, 13, 2600. https://doi.org/10.3390/jcm13092600
Iadevaia C, D’Agnano V, Pagliaro R, Nappi F, Lucci R, Massa S, Bianco A, Perrotta F. Diagnostic Accuracy of Ultrasound Guided Percutaneous Pleural Needle Biopsy for Malignant Pleural Mesothelioma. Journal of Clinical Medicine. 2024; 13(9):2600. https://doi.org/10.3390/jcm13092600
Chicago/Turabian StyleIadevaia, Carlo, Vito D’Agnano, Raffaella Pagliaro, Felice Nappi, Raffaella Lucci, Simona Massa, Andrea Bianco, and Fabio Perrotta. 2024. "Diagnostic Accuracy of Ultrasound Guided Percutaneous Pleural Needle Biopsy for Malignant Pleural Mesothelioma" Journal of Clinical Medicine 13, no. 9: 2600. https://doi.org/10.3390/jcm13092600