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Review

Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups

by
Edmilson Leal Bastos de Moura
1,2,* and
Rinaldo Wellerson Pereira
1,3
1
Health Sciences Doctoral Program, University of Brasília (UnB), Brasilia 70910-900, Distrito Federal, Brazil
2
School of Health Sciences, Distrito Federal University (UnDF), Brasilia 70710-907, Distrito Federal, Brazil
3
Genomic Sciences and Biotechnology Graduate Program, Catholic University of Brasilia, Brasilia 71966-700, Distrito Federal, Brazil
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(23), 7038; https://doi.org/10.3390/jcm13237038
Submission received: 20 September 2024 / Revised: 29 October 2024 / Accepted: 31 October 2024 / Published: 21 November 2024
(This article belongs to the Special Issue Clinical Advances in Critical Care Medicine)

Abstract

Sepsis is a pervasive condition that affects individuals of all ages, with significant social and economic consequences. The early diagnosis of sepsis is fundamental for establishing appropriate treatment and is based on warning scores and clinical characteristics, with positive microbiological cultures being the gold standard. Research has yet to identify a single biomarker to meet this diagnostic demand. Presepsin is a molecule that has the potential as a biomarker for diagnosing sepsis. In this paper, we present a narrative review of the diagnostic and prognostic performance of presepsin in different age groups. Given its particularities, it is identified that presepsin is a potential biomarker for sepsis at all stages of life.
Keywords: sepsis; biomarkers; presepsin; elderly; neonates; adults sepsis; biomarkers; presepsin; elderly; neonates; adults

Share and Cite

MDPI and ACS Style

de Moura, E.L.B.; Pereira, R.W. Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups. J. Clin. Med. 2024, 13, 7038. https://doi.org/10.3390/jcm13237038

AMA Style

de Moura ELB, Pereira RW. Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups. Journal of Clinical Medicine. 2024; 13(23):7038. https://doi.org/10.3390/jcm13237038

Chicago/Turabian Style

de Moura, Edmilson Leal Bastos, and Rinaldo Wellerson Pereira. 2024. "Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups" Journal of Clinical Medicine 13, no. 23: 7038. https://doi.org/10.3390/jcm13237038

APA Style

de Moura, E. L. B., & Pereira, R. W. (2024). Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups. Journal of Clinical Medicine, 13(23), 7038. https://doi.org/10.3390/jcm13237038

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