Diagnostic Errors in Obstetric Morbidity and Mortality: Methods for and Challenges in Seeking Diagnostic Excellence
Abstract
1. Introduction
2. Methods: Selected Approaches to Identifying Diagnostic Errors
- (1)
- Clinicopathologic autopsy research
- (2)
- Retrospective chart review of clinical criteria
- (3)
- Obstetric simulation and standardized patients
- (4)
- Pregnancy-related or -associated morbidity and mortality case reviews
- (5)
- Malpractice and administrative claims databases
3. Discussion: Promoting Diagnostic Excellence in Obstetrics
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Hoyert, D.L. Maternal Mortality Rates in the United States, 2022. National Center for Health Statistics Health E-Stats 2023. Available online: https://www.cdc.gov/nchs/data/hestat/maternal-mortality/2022/maternal-mortality-rates-2022.pdf (accessed on 30 April 2024).
- Ashford, L. Hidden Suffering: Disabilities from Pregnancy and Childbirth in Less Developed Countries; Population Reference Bureau: Washington, DC, USA, 2002. [Google Scholar]
- Reichenheim, M.E.; Zylbersztajn, F.; Moraes, C.L.; Lobato, G. Severe acute obstetric morbidity (near-miss): A review of the relative use of its diagnostic indicators. Arch. Gynecol. Obstet. 2009, 280, 337–343. [Google Scholar] [CrossRef] [PubMed]
- Trost, S.L.; Busacker, A.; Leonard, M.; Chandra, G.; Hollier, L.; Goodman, D.; Wright, M.; Harvey, A.; Joseph, N. Pregnancy-Related Deaths: Data from Maternal Mortality Review Committees in 38, U.S. States, 2020; Centers for Disease Control and Prevention, US Department of Health and Human Services: Atlanta, GA, USA, 2024. [Google Scholar]
- New York State Department of Health. New York State Report on Pregnancy-Associated Deaths in 2018. Available online: https://www.health.ny.gov/community/adults/women/docs/maternal_mortality_review_2018.pdf (accessed on 30 April 2024).
- National Academies of Sciences, Engineering, and Medicine. Improving Diagnosis in Health Care; The National Academies Press: Washington, DC, USA, 2015. [Google Scholar]
- Graber, M.L. The incidence of diagnostic error in medicine. BMJ Qual. Saf. 2013, 22 (Suppl. 2), ii21–ii27. [Google Scholar] [CrossRef] [PubMed]
- Leape, L.L.; Brennan, T.A.; Laird, N.; Lawthers, A.G.; Localio, A.R.; Barnes, B.A.; Hebert, L.; Newhouse, J.P.; Weiler, P.C.; Hiatt, H. Nature of Adverse Events in Hospitalized Patients—Results of the Harvard Medical Practice Study II. NEJM 1991, 324, 377–384. [Google Scholar] [CrossRef] [PubMed]
- Shojania, K.G.; Burton, E.C.; McDonald, K.M.; Goldman, L. Changes in rates of autopsy-detected diagnostic errors over time: A systematic review. JAMA 2003, 289, 2849–2856. [Google Scholar] [CrossRef]
- Newman-Toker, D.E.; Wang, Z.; Zhu, Y.; Nassery, N.; Saber Tehrani, A.S.; Schaffer, A.C.; Yu-Moe, C.W.; Clemens, G.D.; Fanai, M.; Siegal, D. Rate of diagnostic errors and serious misdiagnosis-related harms for major vascular events, infections, and cancers: Toward a national incidence estimate using the “Big Three”. Diagnosis 2020, 8, 67–84. [Google Scholar] [CrossRef] [PubMed]
- Saber Tehrani, A.S.; Lee, H.; Mathews, S.C.; Shore, A.; Makary, M.A.; Pronovost, P.J.; Newman-Toker, D.E. 25-Year summary of US malpractice claims for diagnostic errors 1986–2010: An analysis from the National Practitioner Data Bank. BMJ Qual. Saf. 2013, 22, 672–680. [Google Scholar] [CrossRef] [PubMed]
- Newman-Toker, D.E.; Nassery, N.; Schaffer, A.C.; Yu-Moe, C.W.; Clemens, G.D.; Wang, Z.; Zhu, Y.; Saber Tehrani, A.S.; Fanai, M.; Hassoon, A.; et al. Burden of serious harms from diagnostic error in the USA. BMJ Qual. Saf. 2024, 33, 109–120. [Google Scholar] [CrossRef]
- Newman-Toker, D.E. Diagnostic value: The economics of high-quality diagnosis and a value-based perspective on diagnostic innovation. In Proceedings of the Modern Healthcare Annual Patient Safety & Quality Virual Conference, Virtual, 17 June 2015. [Google Scholar]
- Schiff, G.D. Diagnosis and diagnostic errors: Time for a new paradigm. BMJ Qual. Saf. 2014, 23, 8–16. [Google Scholar] [CrossRef] [PubMed]
- Bajaj, K.; de Roche, A.; Goffman, D. The Contribution of Diagnostic Errors to Maternal Morbidity and Mortality during and Immediately after Childbirth: State of the Science; Issue Brief 6; Agency for Healthcare Research and Quality: Rockville, MD, USA, 2021. [Google Scholar]
- Singh, H.; Sittig, D.F. Advancing the science of measurement of diagnostic errors in healthcare: The Safer Dx framework. BMJ Qual. Saf. 2015, 24, 103–110. [Google Scholar] [CrossRef]
- Miller, C.R.; Johnston, R.D.; Blake, B.H. Pilot study of a method for prospective reporting of diagnostic errors discovered at autopsy. Am. J. Forensic. Med. Pathol. 2023, 44, 166–172. [Google Scholar] [CrossRef]
- Kuijpers, C.C.; Fronczek, J.; van de Goot, F.R.; Niessen, H.W.; van Diest, P.J.; Jiwa, M. The value of autopsies in the era of high-tech medicine: Discrepant findings persist. J. Clin. Pathol. 2014, 67, 512–519. [Google Scholar] [CrossRef] [PubMed]
- Aalten, C.M.; Samson, M.M.; Jansen, P.A.F. Diagnostic errors; the need to have autopsies. Neth. J. Med. 2006, 64, 186–190. [Google Scholar] [PubMed]
- Menéndez, C.; Quintó, L.; Castillo, P.; Fernandes, F.; Carrilho, C.; Ismail, M.R.; Lorenzoni, C.; Hurtado, J.C.; Rakislova, N.; Munguambe, K.; et al. Quality of care and maternal mortality in a tertiary-level hospital in Mozambique: A retrospective study of clinicopathological discrepancies. Lancet Glob. Health 2020, 8, 3965–3972. [Google Scholar] [CrossRef] [PubMed]
- Dror, I.; Melinek, J.; Arden, J.L.; Kukucka, J.; Hawkins, S.; Carter, J.; Atherton, D.S. Cognitive bias in forensic pathology decisions. J. Forensic. Sci. 2021, 66, 1751–1757. [Google Scholar] [CrossRef]
- Rinke, M.L.; Singh, H.; Heo, M.; Adelman, J.S.; O’Donnell, H.C.; Choi, S.J.; Norton, A.; Stein, R.E.K.; Brady, T.M.; Lehmann, C.U.; et al. Diagnostic errors in primary care pediatrics: Project, RedDE. Acad. Pediatr. 2018, 18, 220–227. [Google Scholar] [CrossRef] [PubMed]
- Descargues, G.; Pitette, P.; Gravier, A.; Roman, H.; Lemoine, J.P.; Marpeau, L. Missed diagnosis of postpartum hemorrhage. J. Gynecol. Obstet. Biol. Reprod. 2001, 30, 590–600. [Google Scholar]
- Anderst, J.; Nielsen-Parker, M.; Moffatt, M.; Frazier, T.; Kennedy, C. Using simulation to identify sources of medical diagnostic error in child physical abuse. Child Abus. Negl. 2016, 52, 62–69. [Google Scholar] [CrossRef] [PubMed]
- Lobos, A.T.; Ward, N.; Farion, K.J.; Creery, D.; Fitzgibbons, C.; Ramsay, C.; Hogue, M.; Langevin, M. Simulation-based event analysis improves error discovery and generates improved strategies for error prevention. Simul. Healthc. 2019, 14, 209–216. [Google Scholar] [CrossRef]
- Shimkhada, R.; Solon, O.; Tamondong-Lachica, D.; Peabody, J.W. Misdiagnosis of obstetrical cases and the clinical and cost consequences to patients: A cross-sectional study of urban providers in the Philippines. Glob. Health Action 2016, 9, 32672. [Google Scholar] [CrossRef] [PubMed]
- The Joint Commission. Provision of Care, Treatment, and Services Standards for Maternal Safety. R3 Report 2019, Issue 24. Available online: https://www.jointcommission.org/-/media/tjc/documents/standards/r3-reports/r3-issue-24-maternal-12-7-2021.pdf (accessed on 30 April 2024).
- Centers for Disease Control. About Maternal Mortality Review Committees. Available online: https://www.cdc.gov/maternal-mortality/php/mmrc/index.html (accessed on 30 April 2024).
- Guttmacher Institute. State Laws and Policies: Maternal Mortality Review Committees. Available online: https://www.guttmacher.org/state-policy/explore/maternal-mortality-review-committees (accessed on 30 April 2024).
- Watari, T.; Tokuda, Y.; Mitsuhashi, S.; Otuki, K.; Kono, K.; Nagai, N.; Onigata, K.; Kanda, H. Factors and impact of physicians’ diagnostic errors in malpractice claims in Japan. PLoS ONE 2020, 15, 30237145. [Google Scholar] [CrossRef]
- Gupta, A.; Snyder, A.; Kachalia, A.; Flanders, S.; Saint, S.; Chopra, V. Malpractice claims related to diagnostic errors in the hospital. BMJ Qual. Saf. 2018, 27, 53–60. [Google Scholar] [CrossRef] [PubMed]
- Santhosh, L.; Cornell, E.; Rojas, J.C. Diagnostic Safety across Transitions of Care Throughout the Healthcare System: Current State and a Call to Action; Issue Brief 11; Agency for Healthcare Research and Quality: Rockville, MD, USA, 2023. [Google Scholar]
- Johnson, T.; McNutt, R.; Odwazny, R.; Patel, D.; Baker, S. Discrepancy between admission and discharge diagnoses as a predictor of hospital length of stay. J. Hosp. Med. 2009, 4, 234–239. [Google Scholar] [CrossRef] [PubMed]
- McNutt, R.; Johnson, T.; Kane, J.; Ackerman, M.; Odwazny, R.; Bardhan, J. Cost and quality implications of discrepancies between admitting and discharge diagnoses. Qual. Manag. Health Care 2012, 21, 220–227. [Google Scholar] [CrossRef] [PubMed]
- Eames, J.; Eisenman, A.; Schuster, R.J. Disagreement between emergency department admission diagnosis and hospital discharge diagnosis: Mortality and morbidity. Diagnosis 2016, 3, 23–30. [Google Scholar] [CrossRef] [PubMed]
- Sacco, A.Y.; Self, Q.R.; Worswick, E.L. Patients’ perspectives of diagnostic error: A qualitative study. J. Patient Saf. 2021, 17, e1759–e1764. [Google Scholar] [CrossRef]
- Aoki, T.; Watanuki, S. Multimorbidity and patient-reported diagnostic errors in the primary care setting: Multicentre cross-sectional study in Japan. BMJ Open 2020, 10, e039040. [Google Scholar] [CrossRef] [PubMed]
- Bontempto, A.C.; Mikesell, L. Patient perceptions of misdiagnosis of endometriosis: Results from an online national survey. Diagnosis 2020, 7, 97–106. [Google Scholar] [CrossRef] [PubMed]
- Atallah, F.; Hamm, R.F.; Davidson, C.M.; Combs, C.A.; Patient Safety and Quality Committee. Society for Maternal-Fetal Medicine special statement: Cognitive bias and medical error in obstetrics—Challenges and opportunities. AJOG 2022, 227, B2–B10. [Google Scholar] [CrossRef]
- Penner, L.A.; Blair, I.V.; Albrecht, T.L.; Dovidio, J.F. Reducing racial health care disparities: A social psychological analysis. Policy Insights Behav. Brain Sci. 2014, 1, 204–212. [Google Scholar] [CrossRef]
- van Ryn, M.; Burgess, D.J.; Dovidio, J.F.; Phelan, S.M.; Saha, S.; Malat, J.; Griffin, J.M.; Fu, S.S.; Perry, S. The impact of racism on clinician cognition, behavior, and clinical decision making. Du Bois Rev. 2011, 8, 199–218. [Google Scholar] [CrossRef]
- Hall, W.J.; Chapman, M.V.; Lee, K.M.; Merino, Y.M.; Thomas, T.W.; Payne, B.K.; Eng, E.; Day, S.H.; Coyne-Beasley, T. Implicit racial/ethnic bias among health care professionals and its influence on health care outcomes: A systematic review. Am. J. Public Health 2015, 105, e60–e76. [Google Scholar] [CrossRef]
- Bokka, L.; Ciuffo, F.; Clapper, T.C. Why simulation matters: A systematic review on medical errors occurring during simulated health care. J. Patient Saf. 2024, 20, 110–118. [Google Scholar] [CrossRef] [PubMed]
- ACOG District II. Maternal Safety Bundle for Maternal Early Warning Systems in Pregnancy. Available online: https://www.acog.org/-/media/project/acog/acogorg/files/forms/districts/smi-mews-bundle.pdf (accessed on 30 April 2024).
- The Alliance for Innovation on Maternal Health. Postpartum Discharge Transition Bundle. Available online: https://saferbirth.org/wp-content/uploads/U3-FINAL_AIM_Bundle_PPDT.pdf (accessed on 30 April 2024).
- Murphy, D.R.; Meyer, A.N.; Sittig, D.F.; Meeks, D.W.; Thomas, E.J.; Singh, H. Application of electronic trigger tools to identify targets for improving diagnostic safety. BMJ Qual. Saf. 2019, 28, 151–159. [Google Scholar] [CrossRef]
- Adelman, J.S.; Kalkut, G.E.; Schechter, C.B.; Weiss, J.M.; Berger, M.A.; Reissman, S.H.; Cohen, H.W.; Lorenzen, S.J.; Burack, D.A.; Southern, W.N. Understanding and preventing wrong-patient electronic orders: A randomized controlled trial. J. Am. Med. Inform. Assoc. 2013, 20, 305–310. [Google Scholar] [CrossRef] [PubMed]
- Bradford, A.; Singh, H. Measure Dx: A Resource to Identify, Analyze, and Learn from Diagnostic Safety Events; Agency for Healthcare Research and Quality: Rockville, MD, USA, 2022. [Google Scholar]
Research Method | Pros | Cons |
---|---|---|
Clinicopathologic autopsy studies |
|
|
Retrospective chart review based on clinical criteria |
|
|
Obstetric simulation and standardized patients |
|
|
Pregnancy-related case reviews (incident reporting and maternal mortality reviews) |
|
|
Malpractice and administrative claims database queries |
|
|
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Krenitsky, N.M.; Perez-Urbano, I.; Goffman, D. Diagnostic Errors in Obstetric Morbidity and Mortality: Methods for and Challenges in Seeking Diagnostic Excellence. J. Clin. Med. 2024, 13, 4245. https://doi.org/10.3390/jcm13144245
Krenitsky NM, Perez-Urbano I, Goffman D. Diagnostic Errors in Obstetric Morbidity and Mortality: Methods for and Challenges in Seeking Diagnostic Excellence. Journal of Clinical Medicine. 2024; 13(14):4245. https://doi.org/10.3390/jcm13144245
Chicago/Turabian StyleKrenitsky, Nicole M., India Perez-Urbano, and Dena Goffman. 2024. "Diagnostic Errors in Obstetric Morbidity and Mortality: Methods for and Challenges in Seeking Diagnostic Excellence" Journal of Clinical Medicine 13, no. 14: 4245. https://doi.org/10.3390/jcm13144245
APA StyleKrenitsky, N. M., Perez-Urbano, I., & Goffman, D. (2024). Diagnostic Errors in Obstetric Morbidity and Mortality: Methods for and Challenges in Seeking Diagnostic Excellence. Journal of Clinical Medicine, 13(14), 4245. https://doi.org/10.3390/jcm13144245