Next Article in Journal
Success and Complication Rates of Transvenous Lead Extraction in a Developing High-Volume Extraction Center: The Zurich Experience
Previous Article in Journal
Eosinophilic Esophagitis—What Do We Know So Far?
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 12
Issue 6
10.3390/jcm12062261
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Systematic Review

Oncological and Functional Outcomes for Horizontal Glottectomy: A Systematic Review

by
Matteo Fermi
1,2,†,
Alfredo Lo Manto
3,*,†,
Cecilia Lotto
1,
Giulia Cianci
1,
Francesco Mattioli
3,
Daniele Marchioni
3,
Livio Presutti
1,2 and
Ignacio Javier Fernandez
1
1
Department of Otorhinolaryngology Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, 40138 Bologna, Italy
2
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum, Università di Bologna, 40126 Bologna, Italy
3
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Modena, 41125 Modena, Italy
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
J. Clin. Med. 2023, 12(6), 2261; https://doi.org/10.3390/jcm12062261
Submission received: 26 December 2022 / Revised: 23 February 2023 / Accepted: 11 March 2023 / Published: 14 March 2023
(This article belongs to the Topic Pathogenetic, Diagnostic and Therapeutic Perspectives in Head and Neck Cancer)
Browse Figures
Review Reports Versions Notes

Abstract

Horizontal glottectomy (HG) is a particular type of partial laryngectomy indicated for exclusive glottic tumor with anterior commissure involvement. The purpose of this study is to systematically review the literature about functional and oncological outcome of HG. This systematic review adhered to the recommendations of the PRISMA (Preferred Reporting Items of Systematic Reviews and Meta-analysis) 2009 guidelines. Articles mentioning patients undergoing HG for laryngeal squamous cell carcinoma were included. A total of 14 articles were selected and reviewed from 19 identified. The whole study population consisted of 420 patients who underwent HG. Three hundred and thirty-nine patients out of 359 were staged as T1. The range of post-operative follow-up was 5 months to 10 years. Fifty-five recurrences were experienced, being local, regional and distant in 35, 12 and 8 patients, respectively. Laryngeal preservation rate was 93.6%. Nasogastrict tube was removed on average after 10.1 days. The tracheostomy was maintained for 11.3 days. Mean hospitalization lasted for 11.7 days. According to the results of this systematic review, HG is an oncologically safe surgical option for T1a–T1b glottic tumors with oncological outcomes comparable to other treatment. HG could be a good therapeutical choice whenever poor laryngeal exposure and/or patient’s refusal of radiotherapy are encountered, or when patient’s medical history represents a contraindication for radiation therapy.
Keywords: laryngeal cancer; head and neck cancer; horizontal glottectomy; oncological and functional outcomes laryngeal cancer; head and neck cancer; horizontal glottectomy; oncological and functional outcomes

Share and Cite

MDPI and ACS Style

Fermi, M.; Lo Manto, A.; Lotto, C.; Cianci, G.; Mattioli, F.; Marchioni, D.; Presutti, L.; Fernandez, I.J. Oncological and Functional Outcomes for Horizontal Glottectomy: A Systematic Review. J. Clin. Med. 2023, 12, 2261. https://doi.org/10.3390/jcm12062261

AMA Style

Fermi M, Lo Manto A, Lotto C, Cianci G, Mattioli F, Marchioni D, Presutti L, Fernandez IJ. Oncological and Functional Outcomes for Horizontal Glottectomy: A Systematic Review. Journal of Clinical Medicine. 2023; 12(6):2261. https://doi.org/10.3390/jcm12062261

Chicago/Turabian Style

Fermi, Matteo, Alfredo Lo Manto, Cecilia Lotto, Giulia Cianci, Francesco Mattioli, Daniele Marchioni, Livio Presutti, and Ignacio Javier Fernandez. 2023. "Oncological and Functional Outcomes for Horizontal Glottectomy: A Systematic Review" Journal of Clinical Medicine 12, no. 6: 2261. https://doi.org/10.3390/jcm12062261

APA Style

Fermi, M., Lo Manto, A., Lotto, C., Cianci, G., Mattioli, F., Marchioni, D., Presutti, L., & Fernandez, I. J. (2023). Oncological and Functional Outcomes for Horizontal Glottectomy: A Systematic Review. Journal of Clinical Medicine, 12(6), 2261. https://doi.org/10.3390/jcm12062261

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop