Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine
Abstract
:1. Introduction
2. Materials and Methods
Cell Viability Measurement
3. Results
3.1. DAO Activity Was Not Affected by the Presence of Anti-Inflammatory and Anti-Migraine Drugs
3.2. Effects of Selected Anti-Inflammatory and Anti-Migraine Drugs on Intestinal DAO
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Stovner, L.J.; Nichols, E.; Steiner, T.J.; Abd-Allah, F.; Abdelalim, A.; Al-Raddadi, R.M.; Ansha, M.G.; Barac, A.; Bensenor, I.M.; Doan, L.P.; et al. Global, regional, and national burden of migraine and tension-type headache, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2018, 17, 954–976. [Google Scholar] [CrossRef] [PubMed]
- Stovner, L.J.; Hagen, K.; Linde, M.; Steiner, T.J. The global prevalence of headache: An update, with analysis of the influences of methodological factors on prevalence estimates. J. Headache Pain 2022, 23, 34. [Google Scholar] [CrossRef] [PubMed]
- Kim, B.-K.; Cho, S.-J.; Kim, B.-S.; Sohn, J.-H.; Kim, S.-K.; Cha, M.-J.; Song, T.-J.; Kim, J.-M.; Park, J.W.; Chu, M.K.; et al. Comprehensive Application of the International Classification of Headache Disorders Third Edition, Beta Version. J. Korean Med. Sci. 2016, 31, 106–113. [Google Scholar] [CrossRef] [PubMed]
- Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013, 33, 629–808. [Google Scholar] [CrossRef] [PubMed]
- Ng, J.Y.; Hanna, C. Headache and migraine clinical practice guidelines: A systematic review and assessment of complementary and alternative medicine recommendations. BMC Complement. Med. Ther. 2021, 21, 236. [Google Scholar] [CrossRef] [PubMed]
- Eigenbrodt, A.K.; Ashina, H.; Khan, S.; Diener, H.-C.; Mitsikostas, D.D.; Sinclair, A.J.; Pozo-Rosich, P.; Martelletti, P.; Ducros, A.; Lantéri-Minet, M.; et al. Diagnosis and management of migraine in ten steps. Nat. Rev. Neurol. 2021, 17, 501–514. [Google Scholar] [CrossRef] [PubMed]
- VanderPluym, J.H.; Halker Singh, R.B.; Urtecho, M.; Morrow, A.S.; Nayfeh, T.; Torres Roldan, V.D.; Farah, M.H.; Hasan, B.; Saadi, S.; Shah, S.; et al. Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis. JAMA 2021, 325, 2357–2369. [Google Scholar] [CrossRef]
- Mayans, L.; Walling, A. Acute Migraine Headache: Treatment Strategies. Am. Fam. Physician 2018, 97, 243–251. [Google Scholar]
- Marmura, M.J.; Silberstein, S.D.; Schwedt, T.J. The acute treatment of migraine in adults: The american headache society evidence assessment of migraine pharmacotherapies. Headache 2015, 55, 3–20. [Google Scholar] [CrossRef]
- Nicolas, S.; Nicolas, D. Triptans; StatPearls Publishing: Treasure Island, FL, USA, 2023. [Google Scholar]
- Ong, J.J.Y.; De Felice, M. Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action. Neurother. J. Am. Soc. Exp. Neurother. 2018, 15, 274–290. [Google Scholar] [CrossRef]
- Berger, A.A.; Winnick, A.; Popovsky, D.; Kaneb, A.; Berardino, K.; Kaye, A.M.; Cornett, E.M.; Kaye, A.D.; Viswanath, O.; Urits, I. Lasmiditan for the Treatment of Migraines with or without Aura in Adults. Psychopharmacol. Bull. 2020, 50, 163–188. [Google Scholar] [PubMed]
- Chua, A.L.; Mehla, S.; Orlova, Y.Y. Drug Safety in Episodic Migraine Management in Adults. Part 2: Preventive Treatments. Curr. Pain Headache Rep. 2022, 26, 493–504. [Google Scholar] [CrossRef] [PubMed]
- Kristoffersen, E.S.; Lundqvist, C. Medication-overuse headache: Epidemiology, diagnosis and treatment. Ther. Adv. Drug Saf. 2014, 5, 87–99. [Google Scholar] [CrossRef] [PubMed]
- Branco, A.C.C.C.; Yoshikawa, F.S.Y.; Pietrobon, A.J.; Sato, M.N. Role of Histamine in Modulating the Immune Response and Inflammation. Mediat. Inflamm. 2018, 2018, 9524075. [Google Scholar] [CrossRef] [PubMed]
- Maintz, L.; Novak, N. Histamine and histamine intolerance. Am. J. Clin. Nutr. 2007, 85, 1185–1196. [Google Scholar] [CrossRef]
- Comas-Basté, O.; Sánchez-Pérez, S.; Veciana-Nogués, M.T.; Latorre-Moratalla, M.; Vidal-Carou, M.D.C. Histamine Intolerance: The Current State of the Art. Biomolecules 2020, 10, 1181. [Google Scholar] [CrossRef]
- Izquierdo-Casas, J.; Comas-Basté, O.; Latorre-Moratalla, M.L.; Lorente-Gascón, M.; Duelo, A.; Soler-Singla, L.; Vidal-Carou, M.C. Diamine oxidase (DAO) supplement reduces headache in episodic migraine patients with DAO deficiency: A randomized double-blind trial. Clin. Nutr. 2019, 38, 152–158. [Google Scholar] [CrossRef]
- Mayo-Yáñez, M.; Díaz-Díaz, A.; Vázquez-Barro, J.C.; Herranz González-Botas, J.; Figueroa, A.; Martín-Martín, C.S. Relationship between allergic rhinitis and diamine oxidase activity: A preliminary report. Allergol. Sel. 2021, 5, 187–194. [Google Scholar] [CrossRef]
- Zhao, Y.; Zhang, X.; Jin, H.; Chen, L.; Ji, J.; Zhang, Z. Histamine Intolerance-A Kind of Pseudoallergic Reaction. Biomolecules 2022, 12, 454. [Google Scholar] [CrossRef]
- Cucca, V.; Ramirez, G.A.; Pignatti, P.; Asperti, C.; Russo, M.; Della-Torre, E.; Breda, D.; Burastero, S.E.; Dagna, L.; Yacoub, M.-R. Basal Serum Diamine Oxidase Levels as a Biomarker of Histamine Intolerance: A Retrospective Cohort Study. Nutrients 2022, 14, 1513. [Google Scholar] [CrossRef]
- Schnedl, W.J.; Lackner, S.; Enko, D.; Schenk, M.; Holasek, S.J.; Mangge, H. Evaluation of symptoms and symptom combinations in histamine intolerance. Intest. Res. 2019, 17, 427–433. [Google Scholar] [CrossRef] [PubMed]
- Okutan, G.; Ruiz Casares, E.; Perucho Alcalde, T.; Sánchez Niño, G.M.; Penadés, B.F.; Terrén Lora, A.; Torrente Estríngana, L.; López Oliva, S.; San Mauro Martín, I. Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain. Biomedicines 2023, 11, 660. [Google Scholar] [CrossRef] [PubMed]
- Silva, A.C.d.O.; Biasotto-Gonzalez, D.A.; Oliveira, F.H.M.; Andrade, A.O.; Gomes, C.A.F.; de, P.; Lanza, F.; de, C.; Amorim, C.F.; Politti, F. Effect of Osteopathic Visceral Manipulation on Pain, Cervical Range of Motion, and Upper Trapezius Muscle Activity in Patients with Chronic Nonspecific Neck Pain and Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Evid. Based Complement. Alternat. Med. 2018, 2018, 4929271. [Google Scholar] [CrossRef] [PubMed]
- Schnedl, W.J.; Enko, D. Histamine Intolerance Originates in the Gut. Nutrients 2021, 13, 1262. [Google Scholar] [CrossRef] [PubMed]
- García-Martín, E.; Martínez, C.; Serrador, M.; Alonso-Navarro, H.; Ayuso, P.; Navacerrada, F.; Agúndez, J.A.G.; Jiménez-Jiménez, F.J. Diamine oxidase rs10156191 and rs2052129 variants are associated with the risk for migraine. Headache 2015, 55, 276–286. [Google Scholar] [CrossRef] [PubMed]
- Schnedl, W.J.; Schenk, M.; Lackner, S.; Enko, D.; Mangge, H.; Forster, F. Diamine oxidase supplementation improves symptoms in patients with histamine intolerance. Food Sci. Biotechnol. 2019, 28, 1779–1784. [Google Scholar] [CrossRef] [PubMed]
- Siletsky, S.A. Proton Pumps: Molecular Mechanisms, Inhibitors and Activators of Proton Pumping. Int. J. Mol. Sci. 2023, 24, 9070. [Google Scholar] [CrossRef]
- Leitner, R.; Zoernpfenning, E.; Missbichler, A. Evaluation of the inhibitory effect of various drugs / active ingredients on the activity of human diamine oxidase in vitro. Clin. Transl. Allergy 2014, 4, P23. [Google Scholar] [CrossRef]
- Tobajas, Y.; Alemany-Fornés, M.; Samarra, I.; Romero-Giménez, J.; Tintoré, M.; Del Pino, A.; Canela, N.; Del Bas, J.M.; Ortega-Olivé, N.; de Lecea, C.; et al. Interaction of Diamine Oxidase with Psychostimulant Drugs for ADHD Management. J. Clin. Med. 2023, 12, 4666. [Google Scholar] [CrossRef]
- Mettler, L.G.; Brecht, K.; Butterweck, V.; Meyer Zu Schwabedissen, H.E. Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine. Biomed. Pharmacother. 2022, 148, 112698. [Google Scholar] [CrossRef]
- Rokkas, T.; Vaja, S.; Murphy, G.M.; Dowling, R.H. Aminoguanidine blocks intestinal diamine oxidase (DAO) activity and enhances the intestinal adaptive response to resection in the rat. Digestion 1990, 46 (Suppl. S2), 447–457. [Google Scholar] [CrossRef]
- Yang, R.; Chen, H.; Gu, Z. Factors influencing diamine oxidase activity and γ-aminobutyric acid content of fava bean (Vicia faba L.) during germination. J. Agric. Food Chem. 2011, 59, 11616–11620. [Google Scholar] [CrossRef] [PubMed]
- Amiri, P.; Kazeminasab, S.; Nejadghaderi, S.A.; Mohammadinasab, R.; Pourfathi, H.; Araj-Khodaei, M.; Sullman, M.J.M.; Kolahi, A.-A.; Safiri, S. Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities. Front. Neurol. 2021, 12, 800605. [Google Scholar] [CrossRef] [PubMed]
- Stewart, W.F.; Roy, J.; Lipton, R.B. Migraine prevalence, socioeconomic status, and social causation. Neurology 2013, 81, 948–955. [Google Scholar] [CrossRef] [PubMed]
- Carlsen, L.N.; Rouw, C.; Westergaard, M.L.; Nielsen, M.; Munksgaard, S.B.; Bendtsen, L.; Jensen, R.H. Treatment of medication overuse headache: Effect and predictors after 1 year-A randomized controlled trial. Headache 2021, 61, 1112–1122. [Google Scholar] [CrossRef] [PubMed]
- Lipton, R.B. Risk Factors for and Management of Medication-Overuse Headache. Contin. Lifelong Learn. Neurol. 2015, 21, 1118–1131. [Google Scholar] [CrossRef]
- Diener, H.-C.; Dodick, D.; Evers, S.; Holle, D.; Jensen, R.H.; Lipton, R.B.; Porreca, F.; Silberstein, S.; Schwedt, T. Pathophysiology, prevention, and treatment of medication overuse headache. Lancet Neurol. 2019, 18, 891–902. [Google Scholar] [CrossRef]
- González-Hernández, A.; Marichal-Cancino, B.A.; MaassenVanDenBrink, A.; Villalón, C.M. Side effects associated with current and prospective antimigraine pharmacotherapies. Expert Opin. Drug Metab. Toxicol. 2018, 14, 25–41. [Google Scholar] [CrossRef]
- Agúndez, J.A.G.; Ayuso, P.; Cornejo-García, J.A.; Blanca, M.; Torres, M.J.; Doña, I.; Salas, M.; Blanca-López, N.; Canto, G.; Rondon, C.; et al. The diamine oxidase gene is associated with hypersensitivity response to non-steroidal anti-inflammatory drugs. PLoS ONE 2012, 7, e47571. [Google Scholar] [CrossRef]
- Manzotti, G.; Breda, D.; Di Gioacchino, M.; Burastero, S.E. Serum diamine oxidase activity in patients with histamine intolerance. Int. J. Immunopathol. Pharmacol. 2016, 29, 105–111. [Google Scholar] [CrossRef]
- Oskoui, M.; Pringsheim, T.; Holler-Managan, Y.; Potrebic, S.; Billinghurst, L.; Gloss, D.; Hershey, A.D.; Licking, N.; Sowell, M.; Victorio, M.C.; et al. Practice guideline update summary: Acute treatment of migraine in children and adolescents: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2019, 93, 487–499. [Google Scholar] [CrossRef] [PubMed]
- Gallelli, L.; Cione, E.; Peltrone, F.; Siviglia, S.; Verano, A.; Chirchiglia, D.; Zampogna, S.; Guidetti, V.; Sammartino, L.; Montana, A.; et al. Hsa-miR-34a-5p and hsa-miR-375 as Biomarkers for Monitoring the Effects of Drug Treatment for Migraine Pain in Children and Adolescents: A Pilot Study. J. Clin. Med. 2019, 8, 928. [Google Scholar] [CrossRef] [PubMed]
- Gallardo, V.J.; Gómez-Galván, J.B.; Asskour, L.; Torres-Ferrús, M.; Alpuente, A.; Caronna, E.; Pozo-Rosich, P. A study of differential microRNA expression profile in migraine: The microMIG exploratory study. J. Headache Pain 2023, 24, 11. [Google Scholar] [CrossRef] [PubMed]
- Comas-Basté, O.; Latorre-Moratalla, M.L.; Sánchez-Pérez, S.; Veciana-Nogués, M.T.; Vidal-Carou, M.C. In vitro determination of diamine oxidase activity in food matrices by an enzymatic assay coupled to UHPLC-FL. Anal. Bioanal. Chem. 2019, 411, 7595–7602. [Google Scholar] [CrossRef]
- Knights, K.M.; Stresser, D.M.; Miners, J.O.; Crespi, C.L. In Vitro Drug Metabolism Using Liver Microsomes. Curr. Protoc. Pharmacol. 2016, 74, 7.8.1–7.8.24. [Google Scholar] [CrossRef] [PubMed]
- Yoshitomo, A.; Asano, S.; Hozuki, S.; Tamemoto, Y.; Shibata, Y.; Hashimoto, N.; Takahashi, K.; Sasaki, Y.; Ozawa, N.; Kageyama, M.; et al. Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption. Drug Metab. Dispos. 2022, 51, 318–328. [Google Scholar] [CrossRef]
- Wu, Q.Y.; Ma, S.Z.; Zhang, W.W.; Yao, K.B.; Chen, L.; Zhao, F.; Zhuang, Y.Q. Accumulating pathways of γ-aminobutyric acid during anaerobic and aerobic sequential incubations in fresh tea leaves. Food Chem. 2018, 240, 1081–1086. [Google Scholar] [CrossRef]
- Guo, X.-X.; Zeng, Z.; Qian, Y.-Z.; Qiu, J.; Wang, K.; Wang, Y.; Ji, B.-P.; Zhou, F. Wheat Flour, Enriched with γ-Oryzanol, Phytosterol, and Ferulic Acid, Alleviates Lipid and Glucose Metabolism in High-Fat-Fructose-Fed Rats. Nutrients 2019, 11, 1697. [Google Scholar] [CrossRef]
- Hao, H.; Wang, G.; Sun, J.; Ding, Z.; Wu, X.; Roberts, M. Unidirectional Inversion of Ibuprofen in Caco-2 Cells: Developing a Suitable Model for Presystemic Chiral Inversion Study. Biol. Pharm. Bull. 2005, 28, 682–687. [Google Scholar] [CrossRef]
- Yu, L.S.; Zhao, N.P.; Yao, T.W.; Zeng, S. Zolmitriptan uptake by human intestinal epithelial Caco-2 cells. Die Pharm. -Int. J. Pharm. Sci. 2006, 61, 862–865. [Google Scholar]
- Stevenson, C.L.; Augustijns, P.F.; Hendren, R. Use of Caco-2 cells and LC/MS/MS to screen a peptide combinatorial library for permeable structures. Int. J. Pharm. 1999, 177, 103–115. [Google Scholar] [CrossRef] [PubMed]
- Durham, P.L.; Russo, A.F. Regulation of Calcitonin Gene-Related Peptide Secretion by a Serotonergic Antimigraine Drug. J. Neurosci. 1999, 19, 3423–3429. [Google Scholar] [CrossRef] [PubMed]
- Siissalo, S.; Laine, L.; Tolonen, A.; Kaukonen, A.M.; Finel, M.; Hirvonen, J. Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol. Int. J. Pharm. 2010, 383, 24–29. [Google Scholar] [CrossRef] [PubMed]
- Ricchi, P.; Di Palma, A.; Di Matola, T.; Apicella, A.; Fortunato, R.; Zarrilli, R.; Acquaviva, A.M. Aspirin Protects Caco-2 Cells from Apoptosis after Serum Deprivation through the Activation of a Phosphatidylinositol 3-Kinase/AKT/p21Cip/WAF1Pathway. Mol. Pharmacol. 2003, 64, 407–414. [Google Scholar] [CrossRef] [PubMed]
- Kulthong, K.; Duivenvoorde, L.; Sun, H.; Confederat, S.; Wu, J.; Spenkelink, B.; de Haan, L.; Marin, V.; van der Zande, M.; Bouwmeester, H. Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models. Toxicol. Vitr. 2020, 65, 104815. [Google Scholar] [CrossRef]
- Jagannath, V.; Marinova, Z.; Monoranu, C.-M.; Walitza, S.; Grünblatt, E. Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain. Front. Neuroanat. 2017, 11, 31. [Google Scholar] [CrossRef]
- Panina, Y.; Germond, A.; Masui, S.; Watanabe, T.M. Validation of Common Housekeeping Genes as Reference for qPCR Gene Expression Analysis During iPS Reprogramming Process. Sci. Rep. 2018, 8, 8716. [Google Scholar] [CrossRef]
- Quesada-Vázquez, S.; Colom-Pellicer, M.; Navarro-Masip, È.; Aragonès, G.; Del Bas, J.M.; Caimari, A.; Escoté, X. Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice. Nutrients 2021, 13, 3532. [Google Scholar] [CrossRef]
- Beltrán-Ortiz, C.; Peralta, T.; Ramos, V.; Durán, M.; Behrens, C.; Maureira, D.; Guzmán, M.A.; Bastias, C.; Ferrer, P. Standardization of a colorimetric technique for determination of enzymatic activity of diamine oxidase (DAO) and its application in patients with clinical diagnosis of histamine intolerance. World Allergy Organ. J. 2020, 13, 100457. [Google Scholar] [CrossRef]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Tobajas, Y.; Alemany-Fornés, M.; Samarra, I.; Romero-Giménez, J.; Tintoré, M.; del Pino, A.; Canela, N.; del Bas, J.M.; Ortega-Olivé, N.; de Lecea, C.; et al. Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine. J. Clin. Med. 2023, 12, 7502. https://doi.org/10.3390/jcm12237502
Tobajas Y, Alemany-Fornés M, Samarra I, Romero-Giménez J, Tintoré M, del Pino A, Canela N, del Bas JM, Ortega-Olivé N, de Lecea C, et al. Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine. Journal of Clinical Medicine. 2023; 12(23):7502. https://doi.org/10.3390/jcm12237502
Chicago/Turabian StyleTobajas, Yaiza, Marc Alemany-Fornés, Iris Samarra, Jordi Romero-Giménez, Maria Tintoré, Antoni del Pino, Núria Canela, Josep M. del Bas, Nàdia Ortega-Olivé, Carlos de Lecea, and et al. 2023. "Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine" Journal of Clinical Medicine 12, no. 23: 7502. https://doi.org/10.3390/jcm12237502
APA StyleTobajas, Y., Alemany-Fornés, M., Samarra, I., Romero-Giménez, J., Tintoré, M., del Pino, A., Canela, N., del Bas, J. M., Ortega-Olivé, N., de Lecea, C., & Escoté, X. (2023). Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine. Journal of Clinical Medicine, 12(23), 7502. https://doi.org/10.3390/jcm12237502