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Article

Case Reports Study on Methanol Poisoning in King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia

by
Ghadi I. Alqurashi
1,2,
Fahad S. Alqurashi
1,
Khalid M. Alhusayni
1,
Alaa H. Falemban
2,3,
Yosra Z. Alhindi
3,
Safaa M. Alsanosi
3,
Abdullah R. Alzahrani
2,3,
Saeed S. Al-Ghamdi
2,3 and
Nahla Ayoub
2,3,*
1
Pharmacy Department, King Abdulaziz Hospital, Taif 26521, Saudi Arabia
2
Saudi Toxicology Society, Umm Al-Qura University (UQU), Makkah 21955, Saudi Arabia
3
Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University (UQU), Makkah 21955, Saudi Arabia
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2023, 12(13), 4282; https://doi.org/10.3390/jcm12134282
Submission received: 5 February 2023 / Revised: 28 May 2023 / Accepted: 19 June 2023 / Published: 26 June 2023
(This article belongs to the Section Clinical Neurology)
Versions Notes

Abstract

Methanol poisoning is a challenging issue due to its inducing acute multiple organ failures, and especially due to a lack of preparedness, available antidotes, and management protocols. The current study presents six cases of methanol poisoning that attended the emergency department of King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia, between March and November 2022. All of the patients suffered from severe metabolic acidosis and visual impairment following the ingestion of homemade alcoholic beverages and colonia. Three patients were comatose, suffered from post-cardiac pulmonary arrest, and, finally, died, while the other three were non-comatose and discharged from the ICU after improvement. Management was based on clinical symptoms and other laboratory findings due to a shortage of methanol level measurement resources. The antidote, fomepizole, was not given to all of the cases due to its deficiency, and ethanol was given only to one patient due to difficulties in administering it without monitoring its concentration. Methanol poisoning and its outbreak provide insights into the dangers of hazardous homemade alcohol and other pharmaceutical preparations that might be adulterated with methanol, particularly to the shortage of suitable diagnostic testing and antidotes in addition to poor resources for management of intoxicated patients in some regions of Saudi Arabia.
Keywords: methanol poisoning; case reports; metabolic acidosis; visual loss; multi-organ failures; Saudi Arabia methanol poisoning; case reports; metabolic acidosis; visual loss; multi-organ failures; Saudi Arabia

Share and Cite

MDPI and ACS Style

Alqurashi, G.I.; Alqurashi, F.S.; Alhusayni, K.M.; Falemban, A.H.; Alhindi, Y.Z.; Alsanosi, S.M.; Alzahrani, A.R.; Al-Ghamdi, S.S.; Ayoub, N. Case Reports Study on Methanol Poisoning in King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia. J. Clin. Med. 2023, 12, 4282. https://doi.org/10.3390/jcm12134282

AMA Style

Alqurashi GI, Alqurashi FS, Alhusayni KM, Falemban AH, Alhindi YZ, Alsanosi SM, Alzahrani AR, Al-Ghamdi SS, Ayoub N. Case Reports Study on Methanol Poisoning in King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia. Journal of Clinical Medicine. 2023; 12(13):4282. https://doi.org/10.3390/jcm12134282

Chicago/Turabian Style

Alqurashi, Ghadi I., Fahad S. Alqurashi, Khalid M. Alhusayni, Alaa H. Falemban, Yosra Z. Alhindi, Safaa M. Alsanosi, Abdullah R. Alzahrani, Saeed S. Al-Ghamdi, and Nahla Ayoub. 2023. "Case Reports Study on Methanol Poisoning in King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia" Journal of Clinical Medicine 12, no. 13: 4282. https://doi.org/10.3390/jcm12134282

APA Style

Alqurashi, G. I., Alqurashi, F. S., Alhusayni, K. M., Falemban, A. H., Alhindi, Y. Z., Alsanosi, S. M., Alzahrani, A. R., Al-Ghamdi, S. S., & Ayoub, N. (2023). Case Reports Study on Methanol Poisoning in King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia. Journal of Clinical Medicine, 12(13), 4282. https://doi.org/10.3390/jcm12134282

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