Next Article in Journal
Cross-Sectional Imaging Instead of Colonoscopy in Inflammatory Bowel Diseases: Lights and Shadows
Next Article in Special Issue
Prevalence and Rate of Resolution of Left Atrial Thrombus in Patients with Non-Valvular Atrial Fibrillation: A Two-Center Retrospective Real-World Study
Previous Article in Journal
Association of the Posterior Acromion Extension with Glenoid Retroversion: A CT Study in Normal and Osteoarthritic Shoulders
Previous Article in Special Issue
Effectiveness and Safety of Non-Vitamin K Oral Anticoagulants in Non-Valvular Atrial Fibrillation Patients: Results of A Real-World Study in a Metropolitan Area of Northern Italy
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 11
Issue 2
10.3390/jcm11020352
Review Report
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

Anticoagulation Prior to COVID-19 Infection Has No Impact on 6 Months Mortality: A Propensity Score–Matched Cohort Study

J. Clin. Med. 2022, 11(2), 352; https://doi.org/10.3390/jcm11020352
by Marcin Protasiewicz 1,2, Konrad Reszka 2,*, Wojciech Kosowski 1,2, Barbara Adamik 3, Wojciech Bombala 4, Adrian Doroszko 5, Damian Gajecki 5, Jakub Gawryś 5, Maciej Guziński 6, Maria Jedrzejczyk 7, Krzysztof Kaliszewski 8, Katarzyna Kilis-Pstrusinska 9, Bogusława Konopska 10, Agnieszka Kopec 11, Krzysztof Kujawa 4, Anna Langner 1,2, Anna Larysz 2,12, Weronika Lis 2, Lilla Pawlik-Sobecka 13, Joanna Gorka-Dynysiewicz 10, Marta Rosiek-Biegus 11, Agnieszka Matera-Witkiewicz 14, Tomasz Matys 5, Michał Pomorski 15, Mateusz Sokolski 1,2, Janusz Sokołowski 16, Anna Tomasiewicz-Zapolska 2, Katarzyna Madziarska 17,† and Ewa A Jankowska 2,18,†add Show full author list remove Hide full author list
Reviewer 1: Anonymous
Reviewer 2: Anonymous
J. Clin. Med. 2022, 11(2), 352; https://doi.org/10.3390/jcm11020352
Submission received: 5 December 2021 / Revised: 3 January 2022 / Accepted: 6 January 2022 / Published: 12 January 2022
(This article belongs to the Collection Current Advances and Future Directions for Antithrombotic Treatment Strategies)

Round 1

Reviewer 1 Report

Interesting article. Any doubts:
Data from 472 patients are analyzed when 2,070 patients were selected, what happened here? The methodology is not well explained, as well as the distribution of patients with anticoagulation or not.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Protasiewicz et al. presented an elegant manuscript on the outcomes among patients affected by COVID-19 in two different group: patients receiving anticoagulant treatment (AT) prior to COVID-19; and patients receiving no AT prior to COVID-19.

The strenght of this paper lies in the propensity score match (PSM) analysis which reinforces the data presented. Seems resonable that patients receiving anticoagulants had more comorbidities compared to the ones did not receive anticoagulant, that could be particularly evident in the first analysis in which AT group has worst outcomes; however, when analysing in PSM, similar rate in ICU admission, ventilation or cathecolamin usage were reported, as well as for 6-months mortality.

Did you consider the use of anticoagulant during hospitalization for COVID-19? I think you should report this information if available. I suggest to comment this data (or the lack of this data) on the discussion and eventually, adjust for this counfounder the analysis presented.

Do you may want to discuss your result in the light of a previous Meta-analysis in which patients with AF and COVID-19 had worst outcomes (doi:10.3390/jcm10112490). 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Back to TopTop