Predictors and Consequences of Sac Shrinkage after Endovascular Infrarenal Aortic Aneurysm Repair
Abstract
:1. Introduction
2. Materials and Methods
2.1. Exclusion Criteria
2.2. Data Management
2.3. Endpoints
2.4. Statistical Analysis
3. Results
3.1. Population Demographics and Baseline Characteristics
3.2. Sac Shrinkage
3.3. Demographics and Comorbidities
3.4. Aneurysm Morphology
3.5. Endoleaks
3.6. Reintervention
3.7. Instructions for Use
3.8. Survival
4. Discussion
Limitations of the Study
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Patient Characteristics | ||
---|---|---|
Mean Age, years (±SD) | 75.3 (±8.3) | |
N | % | |
ASA score | ||
ASA 2 | 16 | 26.7 |
ASA 3 | 42 | 70.0 |
ASA 4 | 2 | 3.3 |
Male gender | 49 | 81.7 |
Smoking history | 42 | 70.0 |
Cardiac disease | 28 | 46.7 |
Hypertension | 49 | 81.7 |
Diabetes mellitus | 9 | 15.0 |
Dyslipidaemia | 28 | 46.7 |
Chronic renal insufficiency * | 13 | 21.7 |
COPD | 20 | 33.3 |
Antiplatelet therapy | 28 | 46.7 |
Statins | 35 | 58.3 |
Aneurysm Characteristics | Median | IQR |
Aneurysm maximum diameter (mm) | 57 | (54–61) |
Neck length (mm) | 28 | (17–36) |
Neck maximum diameter (mm) | 25 | (24–28) |
Neck angle (degree) | 27 | (21–46) |
Iliac arteries maximum diameter (mm) | 18 | (15–20) |
Thrombus Index (TI) of the sac † | 0.5 | (0–0.5) |
Other Characteristics | N | % or IQR |
Inferior Mesenteric Artery patency | 45/60 | 75.0% |
Number of patent lumbar arteries (±SD) | 5 | (4–7) |
Patient Characteristics | |||
---|---|---|---|
No Shrinkage N = 34 | Shrinkage N = 26 | p-Value | |
Mean Age, years (±SD) | 76.9 ± 7 | 73.2 ± 9 | 0.08 |
N (%) | N (%) | ||
Male gender | 26 (76.5) | 23 (88.5) | 0.32 |
Smoking history | 24 (70.6) | 18 (69.2) | 0.90 |
Hypertension | 24 (70.6) | 25 (96.2) | 0.01 |
Diabetes mellitus | 4 (11.8) | 5 (19.2) | 0.48 |
Dyslipidaemia | 13 (38.2) | 15 (57.7) | 0.19 |
Chronic renal insufficiency * | 8 (23.5) | 5 (19.2) | 0.76 |
COPD | 12 (35.3) | 8 (30.8) | 0.78 |
Antiaggregant therapy | 17 (50.0) | 11 (42.3) | 0.61 |
Statins | 19 (55.9) | 16 (61.5) | 0.79 |
Aneurysm Characteristics | Median (IQR) | Median (IQR) | |
Aneurysm maximum diameter (mm) | 56 (52–60) | 58 (55–62) | 0.14 |
Neck length (mm) | 29 (17–36) | 25 (16–35) | 0.55 |
Neck maximum diameter (mm) | 26 (24–29) | 25(22–28) | 0.41 |
Neck angle (degree) | 28 (23–46) | 25 (16–45) | 0.53 |
Neck thrombus (% of circumference) | 25 (0–50) | 0 (0–43) | 0.21 |
Thrombus Index (TI) of the sac † | 0.50 (0–0.50) | 0.50 (0–0.50) | 0.78 |
Iliac arteries maximum diameter (mm) | 18 (16–20) | 17 (14–20) | 0.26 |
Number of patent lumbar arteries (±SD) | 5 (4–6) | 6 (4–7) | 0.96 |
Other Characteristics | N (%) | N (%) | |
Inferior Mesenteric Artery patency | 26 (76.5) | 19 (73.1) | 0.77 |
Failure to comply with at least one IFU instruction (n = 13 patients) †† | 7 (20.6) | 6 (23.1) | 0.89 |
| 1 (2.9) | 1 (3.8) | 0.85 |
| 2 (5.9) | 2 (7.7) | 0.78 |
| 4 (11.8) | 4 (15.4) | 0.72 |
| 2 (5.9) | 2 (7.7) | 0.78 |
Endoleaks | |||
All endoleaks | 13 (38.2) | 4 (15.4) | 0.08 |
Endoleaks Types I–III | 4 (11.8) | 2 (7.7) | 0.60 |
Endoleaks Type II | 9 (26.5) | 2 (7.7) | 0.08 |
Reinterventions | |||
All Ever secondary interventions | 3 (8.8) | 3 (11.5) | 0.73 |
Index EVAR within IFU N = 48 | Index EVAR outside IFU N = 13 | p-Value | |
---|---|---|---|
Characteristics | N (%) | N (%) | |
All endoleaks | 12 (25.0) | 5 (41.7) | 0.25 |
Endoleaks Type I–III | 2 (4.2) | 4 (33.3) | 0.01 |
Endoleaks Type II | 10 (20.8) | 1 (8.3) | 0.32 |
Reintervention * | 3 (6.3) | 3 (25.0) | 0.05 |
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Vedani, S.M.; Petitprez, S.; Weinz, E.; Corpataux, J.-M.; Déglise, S.; Deslarzes-Dubuis, C.; Côté, E.; Ricco, J.-B.; Saucy, F. Predictors and Consequences of Sac Shrinkage after Endovascular Infrarenal Aortic Aneurysm Repair. J. Clin. Med. 2022, 11, 3232. https://doi.org/10.3390/jcm11113232
Vedani SM, Petitprez S, Weinz E, Corpataux J-M, Déglise S, Deslarzes-Dubuis C, Côté E, Ricco J-B, Saucy F. Predictors and Consequences of Sac Shrinkage after Endovascular Infrarenal Aortic Aneurysm Repair. Journal of Clinical Medicine. 2022; 11(11):3232. https://doi.org/10.3390/jcm11113232
Chicago/Turabian StyleVedani, Sébastien Michel, Séverine Petitprez, Eva Weinz, Jean-Marc Corpataux, Sébastien Déglise, Céline Deslarzes-Dubuis, Elisabeth Côté, Jean-Baptiste Ricco, and François Saucy. 2022. "Predictors and Consequences of Sac Shrinkage after Endovascular Infrarenal Aortic Aneurysm Repair" Journal of Clinical Medicine 11, no. 11: 3232. https://doi.org/10.3390/jcm11113232
APA StyleVedani, S. M., Petitprez, S., Weinz, E., Corpataux, J.-M., Déglise, S., Deslarzes-Dubuis, C., Côté, E., Ricco, J.-B., & Saucy, F. (2022). Predictors and Consequences of Sac Shrinkage after Endovascular Infrarenal Aortic Aneurysm Repair. Journal of Clinical Medicine, 11(11), 3232. https://doi.org/10.3390/jcm11113232