A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions

Coronado, Liani; Perera, Carmen L.; Rios, Liliam; Frías, María T.; Pérez, Lester J.

doi:10.3390/vaccines9020154

Open AccessReview

A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions

by

Liani Coronado

¹,

Carmen L. Perera

¹,

Liliam Rios

²,

María T. Frías

¹ and

Lester J. Pérez

^3,*,†

¹

National Centre for Animal and Plant Health (CENSA), OIE Collaborating Centre for Disaster Risk Reduction in Animal Health, Mayabeque 32700, Cuba

²

Reiman Cancer Research Laboratory, Faculty of Medicine, University of New Brunswick, Saint John, NB E2L 4L5, Canada

³

Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Illinois at Urbana–Champaign, Champaign, IL 61802, USA

^*

Author to whom correspondence should be addressed.

^†

New Affiliation: Virus Discovery Group, Abbott Diagnostics, Abbott Park, IL 60064, USA

Vaccines 2021, 9(2), 154; https://doi.org/10.3390/vaccines9020154

Submission received: 5 January 2021 / Revised: 31 January 2021 / Accepted: 9 February 2021 / Published: 15 February 2021

(This article belongs to the Special Issue Development and Application of New Vaccine against Classical Swine Fever Virus)

Download Versions Notes

Abstract

Classical swine fever (CSF) is, without any doubt, one of the most devasting viral infectious diseases affecting the members of Suidae family, which causes a severe impact on the global economy. The reemergence of CSF virus (CSFV) in several countries in America, Asia, and sporadic outbreaks in Europe, sheds light about the serious concern that a potential global reemergence of this disease represents. The negative aspects related with the application of mass stamping out policies, including elevated costs and ethical issues, point out vaccination as the main control measure against future outbreaks. Hence, it is imperative for the scientific community to continue with the active investigations for more effective vaccines against CSFV. The current review pursues to gather all the available information about the vaccines in use or under developing stages against CSFV. From the perspective concerning the evolutionary viral process, this review also discusses the current problematic in CSF-endemic countries.

Keywords: classical swine fever; vaccine; DIVA concept; genetic variability; multi-epitope vaccines

Share and Cite

MDPI and ACS Style

Coronado, L.; Perera, C.L.; Rios, L.; Frías, M.T.; Pérez, L.J. A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions. Vaccines 2021, 9, 154. https://doi.org/10.3390/vaccines9020154

AMA Style

Coronado L, Perera CL, Rios L, Frías MT, Pérez LJ. A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions. Vaccines. 2021; 9(2):154. https://doi.org/10.3390/vaccines9020154

Chicago/Turabian Style

Coronado, Liani, Carmen L. Perera, Liliam Rios, María T. Frías, and Lester J. Pérez. 2021. "A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions" Vaccines 9, no. 2: 154. https://doi.org/10.3390/vaccines9020154

APA Style

Coronado, L., Perera, C. L., Rios, L., Frías, M. T., & Pérez, L. J. (2021). A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions. Vaccines, 9(2), 154. https://doi.org/10.3390/vaccines9020154

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

A Critical Review about Different Vaccines against Classical Swine Fever Virus and Their Repercussions in Endemic Regions

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI