Vaccination in Aged Care in Australia: A Retrospective Study of Influenza, Herpes Zoster, and Pneumococcal Vaccination
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Setting
2.2. Participants
2.3. Variables
2.4. Statistical Methods
3. Results
3.1. Participants
3.2. Vaccination Rates
3.3. Univariate
Model | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
Covariate | Influenza n = 1108 | Pneumococcal n = 1108 | Herpes zoster n = 1108 | Influenza n = 990 * | Pneumococcal n = 1094 * | Herpes zoster n = 990 * |
Socioeconomic Indexes for Areas (SEIFA) decile | OR 0.91 [95%CI 0.84, 0.98] p = 0.013 | OR 1.00 [95%CI 0.96 1.04] p = 0.846 | OR 0.94 [95%CI 0.89, 1.00] p = 0.038 | OR 0.93 [95%CI 0.85, 1.00] p = 0.062 | - | OR 0.95 [95%CI 0.89, 1.01] p = 0.095 |
Age (years) | OR 1.00 [95%CI 0.97, 1.03] p = 0.955 | OR 0.98 [95%CI 0.97, 1.00] p = 0.052 | OR 0.88 [95%CI 0.86, 0.91] p < 0.001 | - | OR 1.01 [95%CI 0.99, 1.03] p = 0.348 | OR 0.88 [95%CI 0.85, 0.90] p < 0.001 |
Gender | OR 1.02 [95%CI 0.63, 1.65] p = 0.930 | OR 1.11 [95%CI 0.85, 1.43] p = 0.447 | OR 0.77 [95%CI 0.56, 1.07] p = 0.123 | - | - | - |
Influenza vaccination | - | OR 10.63 [95%CI 4.27, 26.49] p < 0.001 | OR 8.77 [95%CI 2.14, 36.01] p = 0.003 | - | OR 8.60 [95%CI 3.43, 21.56] p < 0.001 | OR 10.19 [95%CI 1.36, 76.32] p = 0.024 |
Pneumococcal vaccination | OR 10.63 [95%CI 4.27, 26.49] p < 0.001 | - | OR 5.01 [95%CI 3.55, 7.08] p < 0.001 | OR 14.35 [95%CI 4.46, 46.13] p < 0.001 | - | OR 4.44 [95%CI 3.01, 6.55] p < 0.001 |
Herpes zoster vaccination | OR 8.77 [95%CI 2.14, 36.01] p = 0.003 | OR 5.01 [95%CI 3.55, 7.08] p < 0.001 | - | OR 8.73 [95%CI 1.18, 64.36] p = 0.033 | OR 4.85 [95%CI 3.36, 7.01] p < 0.001 | - |
Alcohol use | OR 0.58 [95%CI 0.32, 1.03] p = 0.076 | OR 1.18 [95%CI 0.81, 1.70] p = 0.387 | OR 1.65 [95%CI 1.06, 2.57] p = 0.026 | OR 0.51 [95%CI 0.27, 0.97] p = 0.039 | - | OR 1.62 [95%CI 0.97, 2.69] p = 0.065 |
Hospitalisation in the last 30 days | OR 0.61 [95%CI 0.30, 1.23] p = 0.165 | OR 0.79 [95%CI 0.50, 1.25] p = 0.316 | OR 0.47 [95%CI 0.22, 0.98] p = 0.044 | OR 0.64 [95%CI 0.29, 1.38] p = 0.253 | - | OR 0.53 [95%CI 0.24, 1.19] p = 0.122 |
Corticosteroid use in the last 3 months | OR 1.79 [95%CI 0.76, 4.19] p = 0.181 | OR 1.12 [95%CI 0.77, 1.62] p = 0.555 | OR 0.99 [95%CI 0.61, 1.61] p = 0.960 | OR 1.59 [95%CI 0.66, 3.84] p = 0.306 | - | - |
3.4. Multivariate
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
ACIR | Australian Childhood Immunisation Register |
AIR | Australian Immunisation Register |
CI | Confidence Interval |
GP | General Practitioner |
GPP | Guidelines for Good Pharmacoepidemiology Practices |
ISPE | International Society for Pharmacoepidemiology |
NIP | National Immunisation Programme |
OR | Odds Ratio |
SEIFA | Socioeconomic Indexes for Areas |
SD | Standard Deviation |
Appendix A
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Level | NSW | Victoria | Queensland | SA | Total | |
---|---|---|---|---|---|---|
N | 347 | 250 | 264 | 247 | 1108 | |
Age at data collection (years), mean (SD) | 86.2 (6.9) | 86.4 (6.9) | 87.3 (7.0) | 86.9 (7.3) | 86.7 (7.0) | |
Age at data collection (years) | 70–74 | 22 (6.4%) | 19 (7.6%) | 6 (2.3%) | 14 (5.7%) | 61 (5.5%) |
75–79 | 46 (13.3%) | 26 (10.4%) | 40 (15.2%) | 36 (14.7%) | 148 (13.4%) | |
80–84 | 63 (18.2%) | 46 (18.4%) | 40 (15.2%) | 44 (18.0%) | 193 (17.5%) | |
85–89 | 100 (28.9%) | 71 (28.4%) | 64 (24.2%) | 46 (18.8%) | 281 (25.4%) | |
90–94 | 78 (22.5%) | 58 (23.2%) | 75 (28.4%) | 74 (30.2%) | 285 (25.8%) | |
95+ | 37 (10.7%) | 30 (12.0%) | 39 (14.8%) | 31 (12.6%) | 137 (12.4%) | |
Gender | Female | 228 (65.7%) | 175 (70.0%) | 173 (65.5%) | 172 (69.6%) | 748 (67.5%) |
Male | 119 (34.3%) | 75 (30.0%) | 91 (34.5%) | 75 (30.4%) | 360 (32.5%) | |
SEIFA Decile, median (range) | 4.0 (1.0, 10.0) | 7.0 (2.0, 10.0) | 6.0 (1.0, 9.0) | 5.0 (2.0, 9.0) | 5.0 (1.0, 10.0) | |
Corticosteroid use in the last 3 months | 43 (12.4%) | 48 (19.2%) | 29 (11.0%) | 13 (5.3%) | 133 (12.0%) | |
Hospitalisation in the last 30 days | 34 (9.8%) | 20 (8.0%) | 24 (9.1%) | 12 (4.9%) | 90 (8.1%) |
NSW | Victoria | Queensland | SA | Total | |
---|---|---|---|---|---|
N | 347 | 250 | 264 | 247 | 1108 |
Influenza vaccine given | 319 (91.9%) | 235 (94.0%) | 235 (89.0%) | 237 (96.0%) | 1026 (92.6%) |
Herpes zoster vaccine given | 61 (18.1%) | 23 (9.2%) | 49 (18.8%) | 51 (20.6%) | 184 (16.8%) |
Pneumococcal vaccine given | 111 (32.0%) | 70 (28.0%) | 140 (53.0%) | 103 (41.7%) | 424 (38.3%) |
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Wiblin, S.; Lai, Y.; Soulsby, N.; Hillen, J. Vaccination in Aged Care in Australia: A Retrospective Study of Influenza, Herpes Zoster, and Pneumococcal Vaccination. Vaccines 2025, 13, 766. https://doi.org/10.3390/vaccines13070766
Wiblin S, Lai Y, Soulsby N, Hillen J. Vaccination in Aged Care in Australia: A Retrospective Study of Influenza, Herpes Zoster, and Pneumococcal Vaccination. Vaccines. 2025; 13(7):766. https://doi.org/10.3390/vaccines13070766
Chicago/Turabian StyleWiblin, Stephen, Yuen Lai, Natalie Soulsby, and Jodie Hillen. 2025. "Vaccination in Aged Care in Australia: A Retrospective Study of Influenza, Herpes Zoster, and Pneumococcal Vaccination" Vaccines 13, no. 7: 766. https://doi.org/10.3390/vaccines13070766
APA StyleWiblin, S., Lai, Y., Soulsby, N., & Hillen, J. (2025). Vaccination in Aged Care in Australia: A Retrospective Study of Influenza, Herpes Zoster, and Pneumococcal Vaccination. Vaccines, 13(7), 766. https://doi.org/10.3390/vaccines13070766