Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Population
- (1)
- residents aged 60 and above who had lived locally for ≥6 months.
- (1)
- individuals who did not agree to participate in the survey;
- (2)
- individuals with contraindications to the influenza vaccine; and
- (3)
- individuals who were unable to comprehend a simple, standardized screening question used to assess cognitive eligibility (e.g., “Do you plan to get a flu shot next year?”). Participants providing an irrelevant or incomprehensible response were excluded.
2.2. Sample Size
- (1)
- Full-subsidy region: p0 = 10%, p1 = 57.5%, B = 0.3 → Initial n ≈ 140
- (2)
- Partial reimbursement region: p0 = 5%, p1 = 39%, B = 0.2 → Initial n ≈ 160
- (3)
- Full self-payment region: p0 = 3%, p1 = 27.4%, B = 0.1 → Initial n ≈ 385
2.3. Survey Methods and Content
2.4. Statistical Analysis
3. Results
3.1. Demographic Characteristics
3.2. Vaccination Status and Influenza Vaccination Intention
3.3. Health Belief Model Scores
3.4. Multivariate Logistic Regression Analysis
3.5. Random Forest Model Analysis
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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| Variable | Free Policy Region (n = 426) | Partial Reimbursement Region (n = 633) | Self-Paid Policy Region (n = 1206) | χ2 Value | p Value |
|---|---|---|---|---|---|
| Region | 0.026 | 0.999 | |||
| Urban | 145 (34.04%) | 214 (33.81%) | 406 (33.67%) | ||
| Urban–rural fringe | 141 (33.10%) | 209 (33.02%) | 400 (33.17%) | ||
| Rural | 140 (32.86%) | 210 (33.18%) | 400 (33.17%) | ||
| Gender | 6.966 | 0.031 | |||
| Male | 208 (48.83%) | 288 (45.50%) | 504 (41.79%) | ||
| Female | 218 (51.27%) | 345 (54.50%) | 702 (58.21%) | ||
| Age (years) | 74.530 | <0.001 | |||
| 60–69 | 145 (34.04%) | 224 (35.36%) | 482 (39.97%) | ||
| 70–79 | 192 (45.07%) | 258 (40.76%) | 449 (37.23%) | ||
| ≥80 | 89 (20.89%) | 151 (23.88%) | 275 (22.80%) | ||
| Living situation | 29.604 | <0.001 | |||
| Living alone | 37 (8.69%) | 59 (9.32%) | 143 (11.86%) | ||
| Living only with spouse | 208 (48.83%) | 283 (44.71%) | 632 (52.40%) | ||
| Living only with children | 76 (17.84%) | 117 (18.48%) | 151 (12.52%) | ||
| Living with spouse and children | 103 (24.18%) | 173 (27.33%) | 280 (23.22%) | ||
| Living in nursing home | 2 (0.47%) | 1 (0.16%) | 0 (0.00%) | ||
| Education level | 275.510 | <0.001 | |||
| No schooling | 149 (34.98%) | 140 (22.12%) | 90 (7.46%) | ||
| Primary school | 166 (38.97%) | 235 (37.12%) | 393 (32.59%) | ||
| Junior high school | 76 (17.84%) | 138 (21.80%) | 441 (36.57%) | ||
| Technical secondary/high school | 24 (5.63%) | 74 (11.69%) | 233 (19.32%) | ||
| College | 7 (1.64%) | 30 (4.74%) | 31 (2.57%) | ||
| University (and above) | 4 (0.94%) | 16 (2.53%) | 18 (1.49%) | ||
| Medical insurance status | 65.785 | <0.001 | |||
| Basic Social Medical Insurance for Urban Employees | 246 (57.75%) | 381 (60.19%) | 520 (43.12%) | ||
| Basic Social Medical Insurance for Urban and Rural Residents | 178 (41.78%) | 243 (38.39%) | 664 (55.06%) | ||
| Government Medical Scheme | 0 (0.00%) | 0 (0.00%) | 5 (0.41%) | ||
| No medical insurance | 2 (0.47%) | 8 (1.26%) | 12 (1.00%) | ||
| Other | 0 (0.00%) | 1 (0.16%) | 5 (0.41%) | ||
| Average monthly family income * | 151.140 | <0.001 | |||
| <$138/month | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) | ||
| $138–$414/month | 27 (6.34%) | 77 (12.16%) | 234 (19.40%) | ||
| $414–$690/month | 114 (26.76%) | 275 (43.44%) | 467 (37.56%) | ||
| $690–$1379/month | 114 (26.76%) | 128 (20.22%) | 237 (19.65%) | ||
| ≥$1.379/month | 88 (20.66%) | 64 (10.11%) | 50 (4.15%) | ||
| Presence of chronic diseases (excluding simple hypertension) | 5.270 | 0.072 | |||
| Yes | 193 (45.31%) | 255 (40.28%) | 470 (38.97%) | ||
| No | 233 (54.69%) | 378 (59.72%) | 736 (61.03%) | ||
| Co-resident family members with illnesses(excluding simple hypertension) | 7.394 | 0.025 | |||
| Yes | 125 (29.34%) | 148 (23.38%) | 279 (23.13%) | ||
| No | 301 (70.66%) | 485 (76.62%) | 927 (76.87%) |
| Variable | Free Policy Region (n = 426) | Partial Reimbursement Region (n = 633) | Self-Paid Policy Region (n = 1206) | χ2 Value | p Value |
|---|---|---|---|---|---|
| Influenza vaccination status | 283.673 | <0.001 | |||
| Yes | 227 (53.29%) | 132 (20.85%) | 164 (13.60%) | ||
| No | 188 (44.13%) | 483 (76.30%) | 989 (82.01%) | ||
| Not sure | 11 (2.58%) | 18 (2.84%) | 53 (4.39%) | ||
| Next-season influenza vaccination intention | 127.759 | <0.001 | |||
| Yes | 293 (68.78%) | 302 (47.71%) | 448 (37.15%) | ||
| No | 133 (31.22%) | 331 (52.29%) | 758 (62.85%) | ||
| Pneumococcal vaccination status | 593.806 | <0.001 | |||
| Yes | 9 (2.11%) | 313 (49.45%) | 90 (7.46%) | ||
| No | 380 (89.20%) | 295 (46.60%) | 1062 (88.06%) | ||
| Not sure | 37 (8.69%) | 25 (3.95%) | 54 (4.48%) | ||
| COVID-19 vaccination status | 1.942 | 0.767 | |||
| Yes | 392 (92.02%) | 587 (92.73%) | 1129 (93.62%) | ||
| No | 22 (5.16%) | 32 (5.06%) | 55 (4.56%) | ||
| Not sure | 12 (2.82%) | 14 (2.21%) | 22 (1.82%) |
| Dimension | Free Policy Region (n = 426) | Partial Reimbursement Region (n = 633) | Self-Paid Policy Region (n = 206) | F Value | p Value | |||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | |||
| Basic influenza knowledge | 11.28 | 1.86 | 9.99 | 1.74 | 10.52 | 1.99 | 57.862 | <0.001 |
| Perceived susceptibility | 16.70 | 3.84 | 15.37 | 3.25 | 15.85 | 3.61 | 17.923 | <0.001 |
| Perceived severity | 17.35 | 4.06 | 17.06 | 3.65 | 18.18 | 3.65 | 21.223 | <0.001 |
| Perceived vaccination benefit | 20.23 | 3.41 | 18.69 | 3.04 | 19.30 | 3.55 | 26.155 | <0.001 |
| Perceived vaccination barriers | 21.72 | 6.20 | 24.38 | 4.79 | 25.26 | 5.25 | 69.604 | <0.001 |
| Action cues | 23.07 | 4.85 | 20.48 | 3.88 | 19.52 | 4.49 | 102.520 | <0.001 |
| Free Policy Region (n = 426) | Partial Reimbursement Region (n = 633) | Self-Paid Policy Region (n = 1206) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dependent Variable | Independent Variable | β | Wald χ2 Value | Adjusted OR (95% CI) | p Value | β | Wald χ2 Value | Adjusted OR (95% CI) | p Value | β | Wald χ2 Value | Adjusted OR (95% CI) | p Value |
| Current-season vaccination behavior | Basic influenza knowledge | 0.080 | 1.468 | 1.083 (0.953–1.235) | 0.226 | 0.025 | 0.138 | 1.026 (0.898–1.172) | 0.710 | 0.043 | 0.748 | 1.044 (0.948–1.150) | 0.387 |
| Perceived susceptibility | −0.014 | 0.135 | 0.986 (0.917–1.060) | 0.713 | 0.121 | 8.676 | 1.128 (1.043–1.225) | 0.003 | 0.064 | 4.797 | 1.066 (1.007–1.129) | 0.029 | |
| Perceived severity | −0.089 | 5.442 | 0.914 (0.847–0.985) | 0.020 | −0.052 | 1.827 | 0.949 (0.880–1.024) | 0.177 | 0.010 | 0.108 | 1.010 (0.952–1.072) | 0.742 | |
| Perceived vaccination benefit | 0.081 | 2.725 | 1.084 (0.985–1.194) | 0.099 | 0.094 | 3.044 | 1.099 (0.989–1.223) | 0.081 | −0.003 | 0.009 | 0.997 (0.935–1.063) | 0.923 | |
| Perceived vaccination barriers | −0.006 | 0.082 | 0.994 (0.957–1.034) | 0.774 | −0.033 | 1.955 | 0.968 (0.924–1.013) | 0.162 | −0.057 | 10.416 | 0.944 (0.911–0.977) | 0.001 | |
| Action cues | 0.195 | 33.975 | 1.215 (1.140–1.300) | <0.001 | 0.192 | 21.984 | 1.211 (1.120~1.315) | <0.001 | 0.133 | 26.461 | 1.142 (1.087–1.202) | <0.001 | |
| Next-season vaccination intention | Basic influenza knowledge | −0.044 | 0.306 | 0.957 (0.818–1.119) | 0.580 | −0.107 | 2.885 | 0.898 (0.793–1.016) | 0.089 | 0.074 | 3.460 | 1.077 (0.996–1.165) | 0.063 |
| Perceived susceptibility | 0.165 | 13.278 | 1.180 (1.081–1.292) | <0.001 | 0.180 | 22.936 | 1.197 (1.113–1.290) | <0.001 | 0.075 | 10.123 | 1.078 (1.029–1.129) | 0.001 | |
| Perceived severity | −0.065 | 2.014 | 0.937 (0.855–1.024) | 0.156 | −0.016 | 0.215 | 0.984 (0.917–1.054) | 0.643 | −0.035 | 2.083 | 0.966 (0.921–1.012) | 0.149 | |
| Perceived vaccination benefit | 0.047 | 0.668 | 1.048 (0.937–1.174) | 0.414 | 0.105 | 5.083 | 1.111 (1.015–1.218) | 0.024 | 0.031 | 1.511 | 1.032 (0.982–1.085) | 0.219 | |
| Perceived vaccination barriers | −0.020 | 0.580 | 0.980 (0.932–1.033) | 0.446 | −0.024 | 1.233 | 0.976 (0.935–1.019) | 0.267 | −0.042 | 9.286 | 0.958 (0.932–0.985) | 0.002 | |
| Action cues | 0.266 | 45.504 | 1.305 (1.212–1.415) | <0.001 | 0.221 | 42.155 | 1.247 (1.169–1.336) | <0.001 | 0.230 | 117.971 | 1.258 (1.208–1.313) | <0.001 | |
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Su, R.; Zhao, H.; Yang, X.; Qin, Y.; Zheng, J.; Liu, X.; Du, X.; Peng, Z. Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies. Vaccines 2025, 13, 1158. https://doi.org/10.3390/vaccines13111158
Su R, Zhao H, Yang X, Qin Y, Zheng J, Liu X, Du X, Peng Z. Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies. Vaccines. 2025; 13(11):1158. https://doi.org/10.3390/vaccines13111158
Chicago/Turabian StyleSu, Rina, Hongting Zhao, Xiaokun Yang, Ying Qin, Jiandong Zheng, Xinyi Liu, Xinwei Du, and Zhibin Peng. 2025. "Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies" Vaccines 13, no. 11: 1158. https://doi.org/10.3390/vaccines13111158
APA StyleSu, R., Zhao, H., Yang, X., Qin, Y., Zheng, J., Liu, X., Du, X., & Peng, Z. (2025). Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies. Vaccines, 13(11), 1158. https://doi.org/10.3390/vaccines13111158

