Evaluation of the Turkish Population’s Perspective on COVID-19 Vaccine Hesitancy and Routine Childhood Vaccine Applications: National Survey Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Type and Place of Research
2.2. Population and Sample of Research
2.3. Inclusion and Exclusion Criteria
2.4. Determination of the Target Population
2.5. Ethics Committee Approval and Financial Support
2.6. Parameters and Scales Used in the Study
2.6.1. Demographic and Social Characteristics Form
2.6.2. Vaccine Hesitancy Scale Adapted to Pandemic (VHS-P)
2.6.3. Anti-Vaccination Scale—Long Form (AVS-LF)
2.7. Statistical Analysis
3. Results
3.1. Geographical Distribution of Participants
3.2. Sociodemographic Characteristics
3.3. Perception of Participants Regarding COVID-19 and Vaccines
3.4. Analysis of Variables Affecting VHS-P Scale Scores
3.5. Analysis of Variables Affecting General AVS-LF Scale Scores
3.6. Total and Sub-Dimensional Reliability Analysis of VHS-P and AVS-LF Scales
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Akbulut, S.; Gokce, A.; Boz, G.; Saritas, H.; Unsal, S.; Ozer, A.; Akbulut, M.S.; Colak, C. Evaluation of Vaccine Hesitancy and Anxiety Levels among Hospital Cleaning Staff and Caregivers during COVID-19 Pandemic. Vaccines 2022, 10, 1426. [Google Scholar] [CrossRef]
- Šiđanin, I.; Njegovan, B.R.; Sokolović, B. Students’ Views on Vaccination against COVID-19 Virus and Trust in Media Information about the Vaccine: The Case of Serbia. Vaccines 2021, 9, 1430. [Google Scholar] [CrossRef]
- Maliki, I.; Elmsellem, H.; Hafez, B.; EL Moussaoui, A.; Reda Kachmar, M.; Ouahbi, A. The psychological properties of the Arabic BDI-II and the psychological state of the general Moroccan population during the mandatory quarantine due to the COVID-19 pandemic. Casp. J. Environ. Sci. 2021, 19, 139–150. [Google Scholar] [CrossRef]
- Sv, P.; Lorenz, J.M.; Ittamalla, R.; Dhama, K.; Chakraborty, C.; Kumar, D.V.S.; Mohan, T. Twitter-Based Sentiment Analysis and Topic Modeling of Social Media Posts Using Natural Language Processing, to Understand People’s Perspectives Regarding COVID-19 Booster Vaccine Shots in India: Crucial to Expanding Vaccination Coverage. Vaccines 2022, 10, 1929. [Google Scholar] [CrossRef]
- Rodrigues, F.; Block, S.; Sood, S. What Determines Vaccine Hesitancy: Recommendations from Childhood Vaccine Hesitancy to Address COVID-19 Vaccine Hesitancy. Vaccines 2022, 10, 80. [Google Scholar] [CrossRef]
- Prasad, N.K.; Lake, R.; Englum, B.R.; Turner, D.J.; Siddiqui, T.; Mayorga-Carlin, M.; Sorkin, J.D.; Lal, B.K. COVID-19 Vaccination Associated With Reduced Postoperative SARS-CoV-2 Infection and Morbidity. Ann. Surg. 2022, 275, 31–36. [Google Scholar] [CrossRef]
- Watson, O.J.; Barnsley, G.; Toor, J.; Hogan, A.B.; Winskill, P.; Ghani, A.C. Global impact of the first year of COVID-19 vaccination: A mathematical modelling study. Lancet Infect. Dis. 2022, 22, 1293–1302. [Google Scholar] [CrossRef] [PubMed]
- Mudenda, S.; Mukosha, M.; Godman, B.; Fadare, J.O.; Ogunleye, O.O.; Meyer, J.C.; Skosana, P.; Chama, J.; Daka, V.; Matafwali, S.K.; et al. Knowledge, Attitudes, and Acceptance of COVID-19 Vaccines among Secondary School Pupils in Zambia: Implications for Future Educational and Sensitisation Programmes. Vaccines 2022, 10, 2140. [Google Scholar] [CrossRef] [PubMed]
- Oztora, S.; Gokcen, G.B.; Dagdeviren, H.N. Anti-Vaccination and Its Growing Importance. Euras J. Fam. Med. 2022, 11, 151–156. [Google Scholar] [CrossRef]
- Dubé, E.; Laberge, C.; Guay, M.; Bramadat, P.; Roy, R.; Bettinger, J. Vaccine hesitancy: An overview. Hum. Vaccin. Immunother. 2013, 9, 1763–1773. [Google Scholar] [CrossRef] [Green Version]
- Miron, V.D.; Toma, A.R.; Filimon, C.; Bar, G.; Craiu, M. Optional Vaccines in Children-Knowledge, Attitudes, and Practices in Romanian Parents. Vaccines 2022, 10, 404. [Google Scholar] [CrossRef] [PubMed]
- Hasanzad, M.; Namazi, H.; Larijani, B. COVID-19 anti-vaccine attitude and hesitancy. J. Diabetes Metab. Disord. 2022, 1–4. [Google Scholar] [CrossRef] [PubMed]
- MacDonald, N.E. Vaccine hesitancy: Definition, scope and determinants. Vaccine 2015, 33, 4161–4164. [Google Scholar] [CrossRef] [PubMed]
- Stein, R.A.; Ometa, O.; Broker, T.R. COVID-19: The Pseudo-Environment and the Need for a Paradigm Change. Germs 2021, 11, 468–477. [Google Scholar] [CrossRef]
- Sengül, U.; Shiraz, S.E.; Eren, M. Economic Activities of Regions of Level 2 According to Statistical Regional Units Classification (NUTS) in Turkey Determining by Using DEA and Tobit Model Application. Yönetim Bilim. Derg. 2013, 11, 75–99. [Google Scholar]
- Vandenbroucke, J.P.; von Elm, E.; Altman, D.G.; Gøtzsche, P.C.; Mulrow, C.D.; Pocock, S.J.; Poole, C.; Schlesselman, J.J.; Egger, M. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and elaboration. Int. J. Surg. 2014, 12, 1500–1524. [Google Scholar] [CrossRef] [Green Version]
- Larson, H.J.; Jarrett, C.; Schulz, W.S.; Chaudhuri, M.; Zhou, Y.; Dube, E.; Schuster, M.; MacDonald, N.E.; Wilson, R. Measuring vaccine hesitancy: The development of a survey tool. Vaccine 2015, 33, 4165–4175. [Google Scholar] [CrossRef] [Green Version]
- Capar, H.; Cinar, F. Vaccine hesitancy scale in pandemics: Turkish validity and Reliability Study. Gevher Nesibe J. Med. Health Sci. 2021, 6, 41–45. [Google Scholar] [CrossRef]
- Kilicarslan, M.G.; Sarigül, B.; Toraman, C.; Sahin, E.M. Development of valid and reliable scale of vaccine hesitancy in Turkish language. Konuralp Med. J. 2020, 12, 420–429. [Google Scholar] [CrossRef]
- Paul, E.; Steptoe, A.; Fancourt, D. Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications. Lancet Reg. Health Eur. 2021, 1, 100012. [Google Scholar] [CrossRef]
- Salmon, D.A.; Dudley, M.Z.; Brewer, J.; Kan, L.; Gerber, J.E.; Budigan, H.; Proveaux, T.M.; Bernier, R.; Rimal, R.; Schwartz, B. COVID-19 vaccination attitudes, values and intentions among United States adults prior to emergency use authorization. Vaccine 2021, 39, 2698–2711. [Google Scholar] [CrossRef] [PubMed]
- Durduran, Y.; Aktuğ-Demir, N.; Demir, L.S.; Kandemir, B.; Duman, İ.; Yücel, M. Social attitude towards COVID-19 vaccine 1 year after the pandemic. Klimik Derg. 2022, 35, 140–146. [Google Scholar] [CrossRef]
- Karaman, D.; Yılmaz, D.; Yılmaz, H. Examining the impact of the fear of Coronavirus (COVID-19) in intern nursing students on anti-vaccination. J. Turk. Fam. Physician 2021, 12, 179–191. [Google Scholar]
- Yilmaz, H.İ.; Turgut, B.; Citlak, G.; Oğulcan, M.; Parali, B.; Engin, M.; Aktas, A.; Alimoğlu, O. People’s View of COVID-19 Vaccine in Turkey. Dicle Med. J. 2021, 48, 583–594. [Google Scholar] [CrossRef]
- Neumann-Böhme, S.; Varghese, N.E.; Sabat, I.; Barros, P.P.; Brouwer, W.; van Exel, J.; Schreyögg, J.; Stargardt, T. Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19. Eur. J. Health Econ. 2020, 21, 977–982. [Google Scholar] [CrossRef] [PubMed]
- Durmaz, N.; Suman, M.; Ersoy, M.; Örün, E. Parents’ Attitudes toward Childhood Vaccines and COVID-19 Vaccines in a Turkish Pediatric Outpatient Population. Vaccines 2022, 10, 1958. [Google Scholar] [CrossRef]
- Gjini, E.; Moramarco, S.; Carestia, M.C.; Cenko, F.; Ylli, A.; Mehmeti, I.; Palombi, L.; Buonomo, E. Parents’ and caregivers’ role toward childhood vaccination in Albania: Assessment of predictors of vaccine hesitancy. Ann. Ig. 2023, 35, 75–83. [Google Scholar] [CrossRef] [PubMed]
- Giambi, C.; Fabiani, M.; D’Ancona, F.; Ferrara, L.; Fiacchini, D.; Gallo, T.; Martinelli, D.; Pascucci, M.G.; Prato, R.; Filia, A.; et al. Parental vaccine hesitancy in Italy—Results from a national survey. Vaccine 2018, 36, 779–787. [Google Scholar] [CrossRef]
- Hadjipanayis, A.; van Esso, D.; Del Torso, S.; Dornbusch, H.J.; Michailidou, K.; Minicuci, N.; Pancheva, R.; Mujkic, A.; Geitmann, K.; Syridou, G.; et al. Vaccine confidence among parents: Large scale study in eighteen European countries. Vaccine 2020, 38, 1505–1512. [Google Scholar] [CrossRef]
- Larson, H.J.; de Figueiredo, A.; Xiahong, Z.; Schulz, W.S.; Verger, P.; Johnston, I.G.; Cook, A.R.; Jones, N.S. The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey. EBioMedicine 2016, 12, 295–301. [Google Scholar] [CrossRef] [Green Version]
- Edwards, B.; Biddle, N.; Gray, M.; Sollis, K. COVID-19 vaccine hesitancy and resistance: Correlates in a nationally representative longitudinal survey of the Australian population. PLoS ONE 2021, 16, e0248892. [Google Scholar] [CrossRef] [PubMed]
- Huang, Y.; Su, X.; Xiao, W.; Wang, H.; Si, M.; Wang, W.; Gu, X.; Ma, L.; Li, L.; Zhang, S.; et al. COVID-19 vaccine hesitancy among different population groups in China: A national multicenter online survey. BMC Infect. Dis. 2022, 22, 153. [Google Scholar] [CrossRef]
- Shekhar, R.; Sheikh, A.B.; Upadhyay, S.; Singh, M.; Kottewar, S.; Mir, H.; Barrett, E.; Pal, S. COVID-19 Vaccine Acceptance among Health Care Workers in the United States. Vaccines 2021, 9, 119. [Google Scholar] [CrossRef]
- Zein, S.; Abdallah, S.B.; Al-Smadi, A.; Gammoh, O.; Al-Awaida, W.J.; Al-Zein, H.J. Factors associated with the unwillingness of Jordanians, Palestinians and Syrians to be vaccinated against COVID-19. PLoS Negl. Trop. Dis. 2021, 15, e0009957. [Google Scholar] [CrossRef] [PubMed]
- Gode, A.; Ertas, H. Investigation of Relationship Between Health Literacy with Anti-Vaccine: A Study on College Students. J. Acad. Value Stud. 2021, 7, 1–14. [Google Scholar]
- Jain, J.; Saurabh, S.; Kumar, P.; Verma, M.K.; Goel, A.D.; Gupta, M.K.; Bhardwaj, P.; Raghav, P.R. COVID-19 vaccine hesitancy among medical students in India. Epidemiol. Infect. 2021, 149, e132. [Google Scholar] [CrossRef] [PubMed]
- Barbieri, D.; Halasz, G.; Bertellini, E.; Gaspari, A.; Melegari, G. COVID-19: Relative Risk of Non-Vaccinated to Vaccinated Individuals. Diseases 2022, 10, 113. [Google Scholar] [CrossRef]
- Parlak, M.E.; Dilek, E. Anti-Vaccination and COVID-19 Vaccine Hesitancy among Adolescents. Med. Rec. 2022, 4, 258–265. [Google Scholar] [CrossRef]
- Aldakhil, H.; Albedah, N.; Alturaiki, N.; Alajlan, R.; Abusalih, H. Vaccine hesitancy towards childhood immunizations as a predictor of mothers’ intention to vaccinate their children against COVID-19 in Saudi Arabia. J. Infect. Public. Health 2021, 14, 1497–1504. [Google Scholar] [CrossRef]
- Kempe, A.; Saville, A.W.; Albertin, C.; Zimet, G.; Breck, A.; Helmkamp, L.; Vangala, S.; Dickinson, L.M.; Rand, C.; Humiston, S.; et al. Parental Hesitancy About Routine Childhood and Influenza Vaccinations: A National Survey. Pediatrics 2020, 146, e20193852. [Google Scholar] [CrossRef]
Geographical Regions | n | % |
---|---|---|
Istanbul Region | 1257 | 27.7 |
Western Anatolia Region | 635 | 14.0 |
Aegean Region | 579 | 12.8 |
Mediterranean Region | 502 | 11.1 |
East Marmara | 408 | 9.0 |
Southeast Anatolia Region | 326 | 7.2 |
West Blacksea | 198 | 4.4 |
West Marmara | 196 | 4.3 |
Middle Anatolia | 142 | 3.1 |
Middle East Anatolia | 138 | 3.0 |
Northeast Anatolia | 91 | 2.0 |
Eastern Black Sea Region | 67 | 1.5 |
Sociodemographic Characteristics | n | % |
---|---|---|
Age groups | ||
≤30 years | 1435 | 31.6 |
31–50 years | 1943 | 42.8 |
≥51 years | 1161 | 25.6 |
Gender | ||
Male | 2303 | 50.7 |
Female | 2236 | 49.3 |
Educational level | ||
Illiterate | 88 | 1.9 |
Elementary school | 461 | 10.2 |
Middle School | 557 | 12.3 |
High school | 1562 | 34.4 |
Associate/Undergraduate | 1752 | 38.6 |
Master/PhD | 119 | 2.6 |
Children | ||
Yes | 3516 | 77.5 |
No | 1023 | 22.5 |
Concomitant chronic diseases | ||
Yes | 1445 | 31.8 |
No | 3094 | 68.2 |
Smoking habit | ||
Yes | 953 | 21.0 |
No | 3586 | 79.0 |
Questions about COVID-19 and Vaccine Awareness | n | % |
---|---|---|
Exposure to COVID-19 | ||
Yes | 927 | 20.4 |
No | 3612 | 79.6 |
Management of COVID-19 | ||
In house | 900 | 97.1 |
Stay in hospital (service) | 14 | 1.5 |
Stay in hospital (ICU) | 8 | 0.9 |
Stay in hospital (ICU- intubated) | 5 | 0.5 |
Vaccination for COVID-19 | ||
Yes | 4239 | 93.4 |
No | 300 | 6.6 |
Doses of COVID-19 vaccines | ||
1 dose | 210 | 5.0 |
2 doses | 1794 | 42.4 |
3 doses | 2153 | 50.8 |
4 doses | 82 | 1.8 |
Postvaccination exposure to COVID-19 | ||
Yes | 1313 | 31.0 |
No | 2926 | 69.0 |
Belief in the protective capacity of the vaccines | ||
Yes | 2799 | 61.7 |
No | 1740 | 38.3 |
Hesitancy towards COVID-19 vaccines | ||
Yes | 2651 | 58.4 |
No | 1888 | 41.6 |
Vaccination status of the children | ||
Yes | 3445 | 98.0 |
No | 71 | 2.0 |
Hesitation towards the vaccination of the children | ||
Yes | 888 | 19.6 |
No | 3651 | 80.4 |
Approval of the legal obligation of vaccination | ||
Yes | 2136 | 47.1 |
No | 1405 | 31 |
No idea | 998 | 22 |
Variables (Median (95% CI)) | VHS-P | p | AVS-LF | p |
---|---|---|---|---|
Age (yr) | <0.001 * | 0.002 * | ||
≤30 years | 28 (28–29) a | 55 (55–57) e | ||
31–50 years | 28 (28–29) a | 53 (53–54) f | ||
≥51 years | 27 (27–28) b | 52 (51–54) f | ||
Gender | <0.001 # | 0.100 # | ||
Male | 27 (27–28) | 53 (53–54) | ||
Female | 28 (28–29) | 54 (54–55) | ||
Educational level | 0.005 * | <0.001 * | ||
Illiterate | 26 (24–28) c | 49 (46–53) | ||
Elementary school | 27 (27–29) c | 53 (52–56) | ||
Middle School | 27 (27–29) | 54 (53–56) | ||
High school | 28 (28–29) d | 55 (55–57) g | ||
Associate/Undergraduate | 27 (27–28) c | 53 (53–54) h | ||
Master’s/PhD | 27 (26–29) | 55 (54–58) | ||
Children | <0.001 # | <0.001 # | ||
Yes | 27 (27–28) | 53 (53–54) | ||
No | 29 (29–30) | 56 (55–58) | ||
Concomitant chronic disease | <0.001 # | 0.102 # | ||
Yes | 27 (27–28) | 53 (53–54) | ||
No | 28 (28–29) | 54 (54–55) | ||
Smoking habit | 0.412 # | 0.509 # | ||
Yes | 27 (27–29) | 55 (54–57) | ||
No | 28 (28–29) | 53 (53–54) |
Variables (Median (95% CI)) | VHS-P | p | AVS-LF | p |
---|---|---|---|---|
Exposure to COVID-19 | 0.339 # | 0.682 # | ||
Yes | 27 (27–28) | 54 (53–55) | ||
No | 28 (28–29) | 54 (54–55) | ||
Vaccination for COVID-19 | <0.001 # | <0.001 # | ||
Yes | 27 (27–28) | 53 (53–54) | ||
No | 34 (32–36) | 62 (60–63) | ||
Belief in the protective effects of the vaccines | <0.001 # | <0.001 # | ||
Yes | 25 (25–26) | 47 (47–48) | ||
No | 33 (33–34) | 62 (62–63) | ||
Hesitancy for COVID-19 vaccines | <0.001 # | |||
Yes | 31 (31–32) | 59 (59–60) | <0.001 # | |
No | 23 (23–24) | 44 (44–45) | ||
Approval of the legal obligation of the vaccination for COVID-19 | <0.001 * | <0.001 * | ||
Yes | 24 (24–25) a | 46 (46–47) d | ||
No | 33 (33–34) b | 63 (63–65)e | ||
No idea | 29 (29–30) c | 55 (55–57)f | ||
Vaccination of the children | <0.001 # | <0.001 # | ||
Yes | 27 (27–28) | 53 (53–54) | ||
No | 32 (30–36) | 61 (59–75) | ||
Hesitation for vaccination of the children | <0.001 # | <0.001 # | ||
Yes | 30 (30–31) | 62 (61–63) | ||
No | 27(27–28) | 51 (51–52) |
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Akbulut, S.; Boz, G.; Ozer, A.; Sahin, T.T.; Colak, C. Evaluation of the Turkish Population’s Perspective on COVID-19 Vaccine Hesitancy and Routine Childhood Vaccine Applications: National Survey Study. Vaccines 2023, 11, 779. https://doi.org/10.3390/vaccines11040779
Akbulut S, Boz G, Ozer A, Sahin TT, Colak C. Evaluation of the Turkish Population’s Perspective on COVID-19 Vaccine Hesitancy and Routine Childhood Vaccine Applications: National Survey Study. Vaccines. 2023; 11(4):779. https://doi.org/10.3390/vaccines11040779
Chicago/Turabian StyleAkbulut, Sami, Gulseda Boz, Ali Ozer, Tevfik Tolga Sahin, and Cemil Colak. 2023. "Evaluation of the Turkish Population’s Perspective on COVID-19 Vaccine Hesitancy and Routine Childhood Vaccine Applications: National Survey Study" Vaccines 11, no. 4: 779. https://doi.org/10.3390/vaccines11040779
APA StyleAkbulut, S., Boz, G., Ozer, A., Sahin, T. T., & Colak, C. (2023). Evaluation of the Turkish Population’s Perspective on COVID-19 Vaccine Hesitancy and Routine Childhood Vaccine Applications: National Survey Study. Vaccines, 11(4), 779. https://doi.org/10.3390/vaccines11040779