Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging
Abstract
:1. Introduction
2. Insights of Duox Functions from the Model Organism C. elegans
3. Tissue Distribution of Duox in C. elegans
4. The Maturation Complex of Duox in C. elegans
5. BLI-3-Generated Hydrogen Peroxide Catalyzes Collagen Crosslinking
6. The Protective Role of BLI-3 in Pathogen Defense
7. BLI-3-Generated ROS as a Signaling Molecule to Activate the Oxidative Stress Response
8. BLI-3-Generated ROS Redox Signaling to SKN-1 to Promote Longevity
9. The Role of NADPH Oxidases during Mammalian Aging
10. Implication of NADPH Oxidases in Human Aging
11. Conclusive Remarks
Funding
Acknowledgments
Conflicts of Interest
References
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Ewald, C.Y. Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging. Antioxidants 2018, 7, 130. https://doi.org/10.3390/antiox7100130
Ewald CY. Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging. Antioxidants. 2018; 7(10):130. https://doi.org/10.3390/antiox7100130
Chicago/Turabian StyleEwald, Collin Y. 2018. "Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging" Antioxidants 7, no. 10: 130. https://doi.org/10.3390/antiox7100130