Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth?
Internal Medicine 3, Department of Medicine—DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
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Antioxidants 2018, 7(1), 12; https://doi.org/10.3390/antiox7010012
Received: 1 November 2017 / Revised: 10 January 2018 / Accepted: 10 January 2018 / Published: 16 January 2018
(This article belongs to the Special Issue Vitamin E)
Obesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity and mortality closely related to cardiovascular disease, malignancies, and cirrhosis. It is believed that oxidative stress is a main player in the development and progression of NAFLD. Currently, a pharmacological approach has become necessary in NAFLD because of a failure to modify lifestyle and dietary habits in most patients. Vitamin E is a potent antioxidant that has been shown to reduce oxidative stress in NAFLD. This review summarizes the biological activities of vitamin E, with a primary focus on its therapeutic efficacy in NAFLD.
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Keywords:
vitamin E; nonalcoholic fatty liver disease; obesity; oxidative stress
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MDPI and ACS Style
Hadi, H.E.; Vettor, R.; Rossato, M. Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? Antioxidants 2018, 7, 12. https://doi.org/10.3390/antiox7010012
AMA Style
Hadi HE, Vettor R, Rossato M. Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? Antioxidants. 2018; 7(1):12. https://doi.org/10.3390/antiox7010012
Chicago/Turabian StyleHadi, Hamza E.; Vettor, Roberto; Rossato, Marco. 2018. "Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth?" Antioxidants 7, no. 1: 12. https://doi.org/10.3390/antiox7010012
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