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Antioxidants 2018, 7(1), 12; https://doi.org/10.3390/antiox7010012

Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth?

Internal Medicine 3, Department of Medicine—DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
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Received: 1 November 2017 / Revised: 10 January 2018 / Accepted: 10 January 2018 / Published: 16 January 2018
(This article belongs to the Special Issue Vitamin E)
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Abstract

Obesity is one of the major epidemics of this millennium, and its incidence is growing worldwide. Following the epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) has become a disease of increasing prevalence and a leading cause of morbidity and mortality closely related to cardiovascular disease, malignancies, and cirrhosis. It is believed that oxidative stress is a main player in the development and progression of NAFLD. Currently, a pharmacological approach has become necessary in NAFLD because of a failure to modify lifestyle and dietary habits in most patients. Vitamin E is a potent antioxidant that has been shown to reduce oxidative stress in NAFLD. This review summarizes the biological activities of vitamin E, with a primary focus on its therapeutic efficacy in NAFLD. View Full-Text
Keywords: vitamin E; nonalcoholic fatty liver disease; obesity; oxidative stress vitamin E; nonalcoholic fatty liver disease; obesity; oxidative stress
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Hadi, H.E.; Vettor, R.; Rossato, M. Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? Antioxidants 2018, 7, 12.

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