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Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes

URD Industrial Agro-Biotechnologies, CEBB, AgroParisTech, 51110 Pomacle, France
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Academic Editor: Soraya Rodriguez-Rojo
Antioxidants 2021, 10(6), 942; https://doi.org/10.3390/antiox10060942
Received: 27 April 2021 / Revised: 6 June 2021 / Accepted: 7 June 2021 / Published: 10 June 2021
Cannabis sativa L. is a controversial crop due to its high tetrahydrocannabinol content varieties; however, the hemp varieties get an increased interest. This paper describes (i) the main categories of phenolic compounds (flavonoids, stilbenoids and lignans) and terpenes (monoterpenes and sesquiterpenes) from C. sativa by-products and their biological activities and (ii) the main extraction techniques for their recovery. It includes not only common techniques such as conventional solvent extraction, and hydrodistillation, but also intensification and emerging techniques such as ultrasound-assisted extraction or supercritical CO2 extraction. The effect of the operating conditions on the yield and composition of these categories of phenolic compounds and terpenes was discussed. A thorough investigation of innovative extraction techniques is indeed crucial for the extraction of phenolic compounds and terpenes from cannabis toward a sustainable industrial valorization of the whole plant. View Full-Text
Keywords: Cannabis sativa L.; by-products; phenolic compounds; terpenes; biological activities; extraction processes; intensification Cannabis sativa L.; by-products; phenolic compounds; terpenes; biological activities; extraction processes; intensification
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MDPI and ACS Style

Isidore, E.; Karim, H.; Ioannou, I. Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes. Antioxidants 2021, 10, 942. https://doi.org/10.3390/antiox10060942

AMA Style

Isidore E, Karim H, Ioannou I. Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes. Antioxidants. 2021; 10(6):942. https://doi.org/10.3390/antiox10060942

Chicago/Turabian Style

Isidore, Emilie, Hamza Karim, and Irina Ioannou. 2021. "Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes" Antioxidants 10, no. 6: 942. https://doi.org/10.3390/antiox10060942

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