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Review

The Impact of a Plant-Based Diet on Gestational Diabetes: A Review

1
Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy
2
Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy
3
Independent Researcher, Via Venezuela 66, 98121 Messina, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Jeffrey Blumberg
Antioxidants 2021, 10(4), 557; https://doi.org/10.3390/antiox10040557
Received: 8 March 2021 / Revised: 30 March 2021 / Accepted: 31 March 2021 / Published: 2 April 2021
(This article belongs to the Special Issue Plant-Based Diets and Their Antioxidant Role in Human Health)
Gestational diabetes mellitus (GDM) represents a challenging pregnancy complication in which women present a state of glucose intolerance. GDM has been associated with various obstetric complications, such as polyhydramnios, preterm delivery, and increased cesarean delivery rate. Moreover, the fetus could suffer from congenital malformation, macrosomia, neonatal respiratory distress syndrome, and intrauterine death. It has been speculated that inflammatory markers such as tumor necrosis factor-alpha (TNF-α), interleukin (IL) 6, and C-reactive protein (CRP) impact on endothelium dysfunction and insulin resistance and contribute to the pathogenesis of GDM. Nutritional patterns enriched with plant-derived foods, such as a low glycemic or Mediterranean diet, might favorably impact on the incidence of GDM. A high intake of vegetables, fibers, and fruits seems to decrease inflammation by enhancing antioxidant compounds. This aspect contributes to improving insulin efficacy and metabolic control and could provide maternal and neonatal health benefits. Our review aims to deepen the understanding of the impact of a plant-based diet on oxidative stress in GDM. View Full-Text
Keywords: inflammation; oxidative stress; gestational diabetes; plant foods; antioxidants; Mediterranean diet inflammation; oxidative stress; gestational diabetes; plant foods; antioxidants; Mediterranean diet
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MDPI and ACS Style

Schiattarella, A.; Lombardo, M.; Morlando, M.; Rizzo, G. The Impact of a Plant-Based Diet on Gestational Diabetes: A Review. Antioxidants 2021, 10, 557. https://doi.org/10.3390/antiox10040557

AMA Style

Schiattarella A, Lombardo M, Morlando M, Rizzo G. The Impact of a Plant-Based Diet on Gestational Diabetes: A Review. Antioxidants. 2021; 10(4):557. https://doi.org/10.3390/antiox10040557

Chicago/Turabian Style

Schiattarella, Antonio, Mauro Lombardo, Maddalena Morlando, and Gianluca Rizzo. 2021. "The Impact of a Plant-Based Diet on Gestational Diabetes: A Review" Antioxidants 10, no. 4: 557. https://doi.org/10.3390/antiox10040557

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