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Please note that, as of 18 July 2017, Microarrays has been renamed to High-Throughput and is now published here.
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Aptamer-Based Screens of Human Body Fluids for Biomarkers

Department of Biomedical Engineering, University of Houston, 3605 Cullen Blvd, Houston, TX 77204, USA
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Academic Editor: Quan-Zhen Li
Microarrays 2015, 4(3), 424-431; https://doi.org/10.3390/microarrays4030424
Received: 31 July 2015 / Revised: 10 September 2015 / Accepted: 18 September 2015 / Published: 22 September 2015
(This article belongs to the Special Issue High-Throughput Microarray for Protein Biomarker Discovery)
In recent years, aptamers have come to replace antibodies in high throughput multiplexed experiments. The aptamer-based biomarker screening technology, which kicked off in 2010, is capable of interrogating thousands of proteins in a very small sample volume. With this new technology, researchers hope to find clinically appropriate biomarkers for a myriad of illnesses by screening human body fluids. In this work, we have reviewed a total of eight studies utilizing aptamer-based biomarker screens of human body fluids, and have highlighted novel protein biomarkers discovered. View Full-Text
Keywords: biomarker; aptamer; diagnostics; immunoassay; microarray biomarker; aptamer; diagnostics; immunoassay; microarray
MDPI and ACS Style

Albaba, D.; Soomro, S.; Mohan, C. Aptamer-Based Screens of Human Body Fluids for Biomarkers. Microarrays 2015, 4, 424-431.

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