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From the third issue of 2017, Microarrays has changed its name to High-Throughput.

Open AccessReview

Aptamer-Based Screens of Human Body Fluids for Biomarkers

Department of Biomedical Engineering, University of Houston, 3605 Cullen Blvd, Houston, TX 77204, USA
Author to whom correspondence should be addressed.
Academic Editor: Quan-Zhen Li
Microarrays 2015, 4(3), 424-431;
Received: 31 July 2015 / Revised: 10 September 2015 / Accepted: 18 September 2015 / Published: 22 September 2015
(This article belongs to the Special Issue High-Throughput Microarray for Protein Biomarker Discovery)
PDF [363 KB, uploaded 22 September 2015]


In recent years, aptamers have come to replace antibodies in high throughput multiplexed experiments. The aptamer-based biomarker screening technology, which kicked off in 2010, is capable of interrogating thousands of proteins in a very small sample volume. With this new technology, researchers hope to find clinically appropriate biomarkers for a myriad of illnesses by screening human body fluids. In this work, we have reviewed a total of eight studies utilizing aptamer-based biomarker screens of human body fluids, and have highlighted novel protein biomarkers discovered. View Full-Text
Keywords: biomarker; aptamer; diagnostics; immunoassay; microarray biomarker; aptamer; diagnostics; immunoassay; microarray
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Albaba, D.; Soomro, S.; Mohan, C. Aptamer-Based Screens of Human Body Fluids for Biomarkers. Microarrays 2015, 4, 424-431.

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