Next Article in Journal
Language Experience Changes Audiovisual Perception
Next Article in Special Issue
Frameless Stereotaxis for Subthalamic Nucleus Deep Brain Stimulation: An Innovative Method for the Direct Visualization of Electrode Implantation by Intraoperative X-ray Control
Previous Article in Journal
The Effects of Trauma, with or without PTSD, on the Transgenerational DNA Methylation Alterations in Human Offsprings
Previous Article in Special Issue
Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Parkinson Disease with Prior Pallidotomy or Thalamotomy
Open AccessReview

Informed Consent Decision-Making in Deep Brain Stimulation

Department of Human Neurosciences (Former Department of Neurology and Psychiatry), “Sapienza” University of Rome, 00185 Rome, Italy
Department of Mental Health, ASL Roma 5, 00034 Colleferro, Italy
Author to whom correspondence should be addressed.
Brain Sci. 2018, 8(5), 84;
Received: 2 May 2018 / Revised: 7 May 2018 / Accepted: 8 May 2018 / Published: 11 May 2018
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious. Initial evidence of DBS efficacy exists for refractory obsessive-compulsive disorder, treatment-resistant major depressive disorder, and impulse control disorders. Ethical concerns have been raised about the use of an invasive surgical approach involving the central nervous system in patients with possible impairment in cognitive functioning and decision-making capacity. Most of the disorders in which DBS has been used might present with alterations in memory, attention, and executive functioning, which may have an impact on the mental capacity to give informed consent to neurosurgery. Depression, anxiety, and compulsivity are also common in DBS candidate disorders, and could also be associated with an impaired capacity to consent to treatment or clinical research. Despite these issues, there is limited empirical knowledge on the decision-making levels of these patients. The possible informed consent issues of DBS will be discussed by focusing on the specific treatable diseases. View Full-Text
Keywords: informed consent; decision-making capacity; deep brain stimulation informed consent; decision-making capacity; deep brain stimulation
MDPI and ACS Style

Mandarelli, G.; Moretti, G.; Pasquini, M.; Nicolò, G.; Ferracuti, S. Informed Consent Decision-Making in Deep Brain Stimulation. Brain Sci. 2018, 8, 84.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop