Characteristics of Microstructural Changes Associated with Glioma Related Epilepsy: A Diffusion Tensor Imaging (DTI) Study
Abstract
1. Introduction
2. Materials and Methods
2.1. Participants
2.2. MRI Acquisition
2.3. Tumor ROI Extraction
2.4. Diffusion Data Processing
2.5. Statistical Analysis
3. Results
3.1. Demographic Characteristics
3.2. Atlas-Based General Analysis of Diffusion Parametric
3.3. TBSS-EP Group versus Control
3.4. TBSS-nEP Group versus Control
4. Discussion
5. Limitation
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Ep | nEp | Con | p-Value | |
---|---|---|---|---|
Age range (mean ± SE) | 43.92 ± 10.82 | 45.00 ± 9.03 | 44.85 ± 3.31 | 0.94 * |
Sex (female/male) | 8/4 | 6/7 | 6/7 | 0.77 ^ |
Histology (HGG/LGG) | 3/9 | 5/8 | / | 0.91 ^ |
Tumor volume (mL) | 50.88 ± 40.48 | 27.76 ± 17.36 | / | 0.25 u |
Cluster Location | Voxel Size of Mean Diffusivity | |
---|---|---|
Ep | nEp | |
Superior.longitudinal.fasciculus.R | 1755 | 1577 |
Superior.corona.radiata.R | 1342 | 1150 |
Inferior.fronto-occipital.fasciculus.R | 488 | 481 |
Cluster Location | Atlas-Based Results | p-Value | ||
---|---|---|---|---|
Ep | nEP | Ep vs. Control | nEp vs. Control | |
Superior.longitudinal.fasciculus.R | 0.4626 ± 0.0286 | 0.4565 ± 0.0304 | 0.03 u | 0.026 u |
Superior.corona.radiata.R | 0.4813 ± 0.0270 | 0.2484 ± 0.0310 | 0.028 u | 0.012 u |
Inferior.fronto-occipital.fasciculus.R | 0.4479 ± 0.0590 | 0.4861 ± 0.0193 | 0.034 u | 0.025 u |
Cluster Location | Voxel Size of Mean Diffusivity | |
---|---|---|
Ep | nEp | |
Cingulum.(cingulate.gyrus).R | 279 | 243 |
Uncinate.fasciculus.R | 46 | 32 |
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Zhang, H.; Zhou, C.; Zhu, Q.; Li, T.; Wang, Y.; Wang, L. Characteristics of Microstructural Changes Associated with Glioma Related Epilepsy: A Diffusion Tensor Imaging (DTI) Study. Brain Sci. 2022, 12, 1169. https://doi.org/10.3390/brainsci12091169
Zhang H, Zhou C, Zhu Q, Li T, Wang Y, Wang L. Characteristics of Microstructural Changes Associated with Glioma Related Epilepsy: A Diffusion Tensor Imaging (DTI) Study. Brain Sciences. 2022; 12(9):1169. https://doi.org/10.3390/brainsci12091169
Chicago/Turabian StyleZhang, Hong, Chunyao Zhou, Qiang Zhu, Tianshi Li, Yinyan Wang, and Lei Wang. 2022. "Characteristics of Microstructural Changes Associated with Glioma Related Epilepsy: A Diffusion Tensor Imaging (DTI) Study" Brain Sciences 12, no. 9: 1169. https://doi.org/10.3390/brainsci12091169
APA StyleZhang, H., Zhou, C., Zhu, Q., Li, T., Wang, Y., & Wang, L. (2022). Characteristics of Microstructural Changes Associated with Glioma Related Epilepsy: A Diffusion Tensor Imaging (DTI) Study. Brain Sciences, 12(9), 1169. https://doi.org/10.3390/brainsci12091169