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Case Report

Autoimmune Vestibulopathy—A Case Series

Department of Neuro-Otology, Royal National ENT and Eastman Dental Hospitals, UCLH, London WC1E 6DG, UK
Department of Neuro-Otology, St Ann’s Hospital, Whittington Health NHS Trust, London N15 3TH, UK
Hospital for Tropical Diseases, UCLH, London WC1E 6JB, UK
London School of Hygiene and Tropical Medicine, University of London, London WC1E 7HT, UK
Department of Radiology, UCLH, London WC1E 6AS, UK
Department of Neuro-Otology and Audiovestibular Medicine, Attikon, University of Athens, 15772 Athens, Greece
Department of Neuro-Otology, Leicester University Hospitals, Leicester LE2 7HL, UK
Centre for Vestibular and Behavioural Neuroscience, Department of Clinical and Movement Neurosciences, University College London, 33 Queen Square, London WC1N 3BG, UK
Author to whom correspondence should be addressed.
Academic Editor: Werner M. Graf
Brain Sci. 2022, 12(3), 306;
Received: 7 February 2022 / Revised: 17 February 2022 / Accepted: 21 February 2022 / Published: 24 February 2022
(This article belongs to the Special Issue Vestibular Neurology)
Autoimmune inner ear disease (AIED) is a rare clinical entity. Its pathogenicity, heterogenous clinical presentation in the context of secondary systemic autoimmune disease and optimal treatment avenues remain poorly understood. Vestibular impairment occurring in the context of AIED is rarely subject to detailed investigation given that the auditory symptoms and their responsiveness to immunosuppression are the focus of the few proposed diagnostic criteria for AIED. We present three cases of vestibulopathy occurring in the context of autoimmune inner ear conditions, including the first known report of autoimmune inner ear pathology arising with a temporal association to administration of the Pfizer-BioNTech SARS-CoV2 vaccination. We review the available literature pertinent to each case and summarise the key learning points, highlighting the variable presentation of vestibular impairment in AIED. View Full-Text
Keywords: AIED; autoimmune; vestibulopathy; vestibular; ulcerative colitis; Cogan syndrome; COVID-19; vaccination AIED; autoimmune; vestibulopathy; vestibular; ulcerative colitis; Cogan syndrome; COVID-19; vaccination
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MDPI and ACS Style

Mendis, S.; Longley, N.; Morley, S.; Korres, G.; Kaski, D. Autoimmune Vestibulopathy—A Case Series. Brain Sci. 2022, 12, 306.

AMA Style

Mendis S, Longley N, Morley S, Korres G, Kaski D. Autoimmune Vestibulopathy—A Case Series. Brain Sciences. 2022; 12(3):306.

Chicago/Turabian Style

Mendis, Surangi, Nicola Longley, Simon Morley, George Korres, and Diego Kaski. 2022. "Autoimmune Vestibulopathy—A Case Series" Brain Sciences 12, no. 3: 306.

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