Next Article in Journal
CINET: A Brain-Inspired Deep Learning Context-Integrating Neural Network Model for Resolving Ambiguous Stimuli
Previous Article in Journal
Surgery for Spine Disease and Intractable Pain
Previous Article in Special Issue
The Role of Movement Representation Techniques in the Motor Learning Process: A Neurophysiological Hypothesis and a Narrative Review
Open AccessArticle

Cerebellar Transcranial Magnetic Stimulation Reduces the Silent Period on Hand Muscle Electromyography During Force Control

1
Faculty of Rehabilitation, Shijonawate Gakuen University, Hojo 5-11-10, Daitou city, Osaka 574-0011, Japan
2
Department of Rehabilitation, National Hospital Organization Kyoto Medical Center, Hukakusamukaihatacyo1-1, Husimi-ku Kyoto City, Kyoto 612-8555, Japan
3
Division of Rehabilitation, Hanna Central Hospital, Ikoma, Nara 630-0243, Japan
4
Department of Neuromodulation and Neurosurgery, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
5
Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
6
Graduate School of Health Sciences, Kio University, 4-2-2 Umami-naka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan
7
Department of Rehabilitation, Baba memorial Hospital, Nishiku Hamaderahunaotyohigashi 4-244, Sakai City, Osaka 592-8555, Japan
8
Institute of Rehabilitation Science, Tokuyukai medical corporation, 3-11-1 Sakuranocho, Toyonaka City, Osaka 560-0054, Japan
9
Kansai Rehabilitation Hospital, 3-11-1 Sakuranocho, Toyonaka City, Osaka 560-0054, Japan
10
National Center Hospital, National Center of Neurology and Psychiatry, Kodaira 187-0031, Japan
11
Department of Rehabilitation for Intractable Neurological Disorders, Institute of Brain and Blood Vessels Mihara Memorial Hospital, Ohtamachi366, Isesaki City, Gunma 372-0006, Japan
12
Neurorehabilitation Research Center of Kio University, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan
*
Author to whom correspondence should be addressed.
Brain Sci. 2020, 10(2), 63; https://doi.org/10.3390/brainsci10020063
Received: 26 November 2019 / Revised: 14 January 2020 / Accepted: 22 January 2020 / Published: 24 January 2020
(This article belongs to the Special Issue Neuromodulation and Executive Control of Human Movements)
: This study aimed to investigate whether cerebellar transcranial magnetic stimulation (C-TMS) affected the cortical silent period (cSP) induced by TMS over the primary motor cortex (M1) and the effect of interstimulus interval (ISI) on cerebellar conditioning and TMS to the left M1 (M1-TMS). Fourteen healthy adult participants were instructed to control the abduction force of the right index finger to 20% of the maximum voluntary contraction. M1-TMS was delivered during this to induce cSP on electromyograph of the right first dorsal interosseous muscle. TMS over the right cerebellum (C-TMS) was conducted prior to M1-TMS. In the first experiment, M1-TMS intensity was set to 1 or 1.3 × resting motor threshold (rMT) with 20-ms ISI. In the second experiment, the intensity was set to 1 × rMT with ISI of 0, 10, 20, 30, 40, 50, 60, 70, or 80 ms, and no-C-TMS trials were inserted. In results, cSP was significantly shorter in 1 × rMT condition than in 1.3 × rMT by C-TMS, and cSP was significantly shorter for ISI of 20–40 ms than for the no-C-TMS condition. Further, motor evoked potential for ISI40-60 ms were significantly reduced than that for ISI0. Thus, C-TMS may reduce cSP induced by M1-TMS with ISI of 20–40 ms.
Keywords: cortical silent period; GABAergic circuit; cerebellum; transcranial magnetic stimulation cortical silent period; GABAergic circuit; cerebellum; transcranial magnetic stimulation
MDPI and ACS Style

Matsugi, A.; Douchi, S.; Suzuki, K.; Oku, K.; Mori, N.; Tanaka, H.; Nishishita, S.; Bando, K.; Kikuchi, Y.; Okada, Y. Cerebellar Transcranial Magnetic Stimulation Reduces the Silent Period on Hand Muscle Electromyography During Force Control. Brain Sci. 2020, 10, 63.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop