Next Article in Journal
Artificial-Hand Technology—Current State of Knowledge in Designing and Forecasting Changes
Next Article in Special Issue
Piperine-A Major Principle of Black Pepper: A Review of Its Bioactivity and Studies
Previous Article in Journal
Special Issue on Advanced Applications for Smart Energy Systems Considering Grid-Interactive Demand Response
Previous Article in Special Issue
Apium Plants: Beyond Simple Food and Phytopharmacological Applications
Review

The Therapeutic Potential of the Labdane Diterpenoid Forskolin

1
Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran
2
Institute of Soil Science and Plant Cultivation—State Research Institute, Czartoryskich Str. 8, 24-100 Puławy, Poland
3
Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia
4
Centre for Inflammation, Centenary Institute, University of Newcastle, Callaghan, NSW 2308, Australia
5
Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW 2308, Australia
6
Faculty of Life Science and Biotechnology, South Asian University, Akbar Bhawan, Chanakyapuri, New Delhi 110021, India
7
Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia
8
Department of Plant Biology Department, Taras Shevchenko National University of Kyiv, Institute of Biology, Volodymyrska str., 64, Kyiv 01033, Ukraine
9
Department of Plant Physiology, Slovak University of Agriculture, Nitra, A. Hlinku 2, 94976 Nitra, Slovak
10
Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, India
11
Department of Chemical, Environmental and Materials Engineering, University of Jaén, 23071 Jaén, Spain
12
Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Dushanbe 73400, Tajikistan
13
Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, China
14
Department of Pharmacology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft 7861756447, Iran
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2019, 9(19), 4089; https://doi.org/10.3390/app9194089
Received: 30 August 2019 / Revised: 20 September 2019 / Accepted: 26 September 2019 / Published: 30 September 2019
Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy. View Full-Text
Keywords: forskolin; plant secondary metabolites; Coleus forskohlii; cAMP pathway forskolin; plant secondary metabolites; Coleus forskohlii; cAMP pathway
Show Figures

Figure 1

MDPI and ACS Style

Salehi, B.; Staniak, M.; Czopek, K.; Stępień, A.; Dua, K.; Wadhwa, R.; Kumar Chellappan, D.; Sytar, O.; Brestic, M.; Ganesh Bhat, N.; Venkatesh Anil Kumar, N.; del Mar Contreras, M.; Sharopov, F.; C. Cho, W.; Sharifi-Rad, J. The Therapeutic Potential of the Labdane Diterpenoid Forskolin. Appl. Sci. 2019, 9, 4089. https://doi.org/10.3390/app9194089

AMA Style

Salehi B, Staniak M, Czopek K, Stępień A, Dua K, Wadhwa R, Kumar Chellappan D, Sytar O, Brestic M, Ganesh Bhat N, Venkatesh Anil Kumar N, del Mar Contreras M, Sharopov F, C. Cho W, Sharifi-Rad J. The Therapeutic Potential of the Labdane Diterpenoid Forskolin. Applied Sciences. 2019; 9(19):4089. https://doi.org/10.3390/app9194089

Chicago/Turabian Style

Salehi, Bahare, Mariola Staniak, Katarzyna Czopek, Anna Stępień, Kamal Dua, Ridhima Wadhwa, Dinesh Kumar Chellappan, Oksana Sytar, Marian Brestic, Namrata Ganesh Bhat, Nanjangud Venkatesh Anil Kumar, María del Mar Contreras, Farukh Sharopov, William C. Cho, and Javad Sharifi-Rad. 2019. "The Therapeutic Potential of the Labdane Diterpenoid Forskolin" Applied Sciences 9, no. 19: 4089. https://doi.org/10.3390/app9194089

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop