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Ten Years of Gabor-Domain Optical Coherence Microscopy

1
LighTopTech Corp., 150 Lucius Gordon Drive, Suite 201, West Henrietta, NY 14586-9687, USA
2
The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
*
Author to whom correspondence should be addressed.
Appl. Sci. 2019, 9(12), 2565; https://doi.org/10.3390/app9122565
Received: 17 April 2019 / Revised: 18 June 2019 / Accepted: 19 June 2019 / Published: 24 June 2019
(This article belongs to the Special Issue Optical Coherence Tomography and its Applications)
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Abstract

Gabor-domain optical coherence microscopy (GDOCM) is a high-definition imaging technique leveraging principles of low-coherence interferometry, liquid lens technology, high-speed imaging, and precision scanning. GDOCM achieves isotropic 2 μm resolution in 3D, effectively breaking the cellular resolution limit of optical coherence tomography (OCT). In the ten years since its introduction, GDOCM has been used for cellular imaging in 3D in a number of clinical applications, including dermatology, oncology and ophthalmology, as well as to characterize materials in industrial applications. Future developments will enhance the structural imaging capability of GDOCM by adding functional modalities, such as fluorescence and elastography, by estimating thicknesses on the nano-scale, and by incorporating machine learning techniques. View Full-Text
Keywords: optical coherence tomography; noninvasive imaging; Gabor-domain optical coherence microscopy optical coherence tomography; noninvasive imaging; Gabor-domain optical coherence microscopy
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Canavesi, C.; Rolland, J.P. Ten Years of Gabor-Domain Optical Coherence Microscopy. Appl. Sci. 2019, 9, 2565.

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