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Open AccessReview

3D Printing Applied to Tissue Engineered Vascular Grafts

1
Cardiology, Faculty of Sciences and medicine, University of Fribourg, 1700 Fribourg, Switzerland
2
University of Bern, 3000 Bern, Switzerland
*
Author to whom correspondence should be addressed.
Appl. Sci. 2018, 8(12), 2631; https://doi.org/10.3390/app8122631
Received: 22 November 2018 / Revised: 5 December 2018 / Accepted: 11 December 2018 / Published: 15 December 2018
The broad clinical use of synthetic vascular grafts for vascular diseases is limited by their thrombogenicity and low patency rate, especially for vessels with a diameter inferior to 6 mm. Alternatives such as tissue-engineered vascular grafts (TEVGs), have gained increasing interest. Among the different manufacturing approaches, 3D bioprinting presents numerous advantages and enables the fabrication of multi-scale, multi-material, and multicellular tissues with heterogeneous and functional intrinsic structures. Extrusion-, inkjet- and light-based 3D printing techniques have been used for the fabrication of TEVG out of hydrogels, cells, and/or solid polymers. This review discusses the state-of-the-art research on the use of 3D printing for TEVG with a focus on the biomaterials and deposition methods. View Full-Text
Keywords: 3D printing; bioprinting; additive manufacturing; tissue engineering; blood vessels; vascular grafting 3D printing; bioprinting; additive manufacturing; tissue engineering; blood vessels; vascular grafting
MDPI and ACS Style

Wenger, R.; Giraud, M.-N. 3D Printing Applied to Tissue Engineered Vascular Grafts. Appl. Sci. 2018, 8, 2631.

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