Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?
AbstractOptical Coherence Tomography Angiography (OCTA) refers to a powerful class of OCT scanning protocols and algorithms that selectively enhance the imaging of blood vessel lumens, based mainly on the motion and scattering of red blood cells (RBCs). Though OCTA is widely used in clinical and basic science applications for visualization of perfused blood vessels, OCTA is still primarily a qualitative tool. However, more quantitative hemodynamic information would better delineate disease mechanisms, and potentially improve the sensitivity for detecting early stages of disease. Here, we take a broader view of OCTA in the context of microvascular hemodynamics and light scattering. Paying particular attention to the unique challenges presented by capillaries versus larger supplying and draining vessels, we critically assess opportunities and challenges in making OCTA a quantitative tool. View Full-Text
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Zhu, J.; Merkle, C.W.; Bernucci, M.T.; Chong, S.P.; Srinivasan, V.J. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Appl. Sci. 2017, 7, 687.
Zhu J, Merkle CW, Bernucci MT, Chong SP, Srinivasan VJ. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Applied Sciences. 2017; 7(7):687.Chicago/Turabian Style
Zhu, Jun; Merkle, Conrad W.; Bernucci, Marcel T.; Chong, Shau P.; Srinivasan, Vivek J. 2017. "Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?" Appl. Sci. 7, no. 7: 687.
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