1. Introduction
Air pollution is defined as high levels of chemical substances or toxic compounds in the air, increasing health risks [
1]. According to the World Health Organization, air pollution primarily affects low- and middle-income countries, with 9 out of 10 people exposed to air pollution levels exceeding WHO-established limits [
2].
As in other cities in developing countries, air pollution in Chile is prevalent in areas with a high concentration of industries, heavy vehicular traffic, and widespread use of wood-burning heating [
3]. Despite existing regulations, pollution persists in some areas, producing significant environmental and health impacts for local communities. To date, environmental pollution control measures have been implemented in Chile, leading to a progressive improvement in air quality; however, these efforts remain insufficient.
Air pollution is closely associated with atmospheric particulate matter (PM), PM
2.5 refers to fine particulate matter with an aerodynamic diameter ≤ 2.5 μm, capable of penetrating deep into the respiratory system and crossing the blood-brain barrier, posing significant health risks, particularly to children. PM
10, or coarse particulate matter with a diameter ≤ 10 μm, primarily affects the up-per respiratory tract but is less likely to reach systemic circulation. This study focuses exclusively on PM
2.5 due to its established neurotoxic effects and relevance to cognitive development [
1]
The main components of PM
2.5 include sulfates, nitrates, ammonium, organic carbon, elemental carbon, and mineral dust, with metals (e.g., copper, lead) and polycyclic aromatic hydrocarbons (PAHs) present in smaller proportions. Regarding size, PM
10 and PM
2.5 have aerodynamic diameters of 10 μm and 2.5 μm and are referred to as coarse and fine particles, respectively. PM
2.5 has been observed to contain organic and inorganic components from various anthropogenic sources, such as copper (Cu) and high-molecular-weight polycyclic aromatic hydrocarbons (PAHs), which are generated from the incomplete combustion of fossil fuels, among others [
1]. The relevance of PM
2.5 lies in the fact that the pollutants it contains have been identified as toxic, especially for development in children [
4].
Children are particularly vulnerable to air pollution due to their developing respiratory and immune systems, lower body mass, and specific breathing patterns, which increase pollutant absorption [
5,
6]. Air quality in schools is an emerging concern, potentially posing even greater health risks than outdoor pollution [
7]. Exposure during this critical developmental stage can negatively affect children’s respiratory, cardiovascular, and cognitive systems [
8,
9], with studies reporting lower neurobehavioral and IQ test scores, as well as neurological impairments, among exposed children [
3,
10,
11].
PM
2.5 can penetrate deep into the lungs, enter systemic circulation, and cross the blood-brain barrier, producing neurotoxic effects during childhood [
12,
13]. Chronic exposure has been associated with neuroinflammation and oxidative stress, particularly in the hippocampus and prefrontal cortex—regions critical for memory and learning [
14,
15,
16]. Both human and animal studies have shown that PM
2.5 exposure alters neuronal function and morphology through mechanisms like microglial activation and disrupted metabolism in key brain areas [
17,
18,
19].
Persistent neuroinflammation and disruption of neuronal homeostasis due to PM
2.5 exposure can impair synaptic circuits, negatively impacting cognitive abilities such as working memory, reasoning, and concentration—key skills for academic performance. These effects have been linked to lower scores in language and mathematics among schoolchildren exposed to high levels of PM
2.5, as observed in both third-grade students and broader school environments like those in California [
20,
21]. A critical mechanism behind this neurotoxicity is PM
2.5’s capacity to carry heavy metals (e.g., lead, mercury, cadmium) and persistent organic compounds, which enhance their absorption into the central nervous system [
13]. Research in rats shows that these metals can accumulate in the cerebral cortex via PM
2.5 transport, increasing neuronal toxicity and contributing to neurodegenerative processes and cognitive decline in children [
13,
22,
23].
It is known that learning and, consequently, academic performance (AP) in children depend on their cognitive functions [
5], which could be affected by exposure to environmental pollution [
7]. Additionally, children with low socioeconomic status (SES), as well as those belonging to ethnic minorities, may show diminished cognitive functions when exposed to environmental pollution in schools [
6]. In this context, Wu et al. (2006) in Detroit found that students attending schools near high-traffic roads or highly polluted industrial areas are more likely to be African American or Hispanic and to live in a low-income area of the city [
6]. Pastor et al. (2006) evaluated children from impoverished communities in California exposed to environmental pollution, finding low results on standardized AP tests [
8]. Another study, conducted by Moahi et al. in 2011, showed that the majority of children exposed to high levels of air pollution in public schools in Michigan performed poorly on standardized academic achievement tests [
9].
Regarding air pollution in Chile, a study by Álamos et al. (2022) found that the residential sector is responsible for over 90% of PM
2.5 and PM
10 emissions. Overall, air pollution and CO
2 emissions from human activities in northern Chile are primarily driven by mining operations and thermoelectric power plants, whereas in central and southern Chile, the main sources are residential heating and transportation [
3].
About academic performance, it is assessed in the country through the Education Quality Measurement System (SIMCE), which is conducted annually under the framework of Law No. 20.529. SIMCE serves as a national assessment tool for measuring student learning outcomes across the country [
10]. Relating both topics, in a recently published study by our research group [
11], we determined the effects of environmental pollution on health risk and the AP of Chilean children attending six schools located in the Quintero and Puchuncaví area one of the country’s sacrifice zones. In this study, we also consider mineral dust, metals (e.g., copper, lead), and polycyclic aromatic hydrocarbons (PAHs) due to their relevance in the Chilean context, where mining, industrial activities, and wood combustion are prevalent emission sources, particularly in areas like Puchuncaví and Quintero, where heavy metal exposure has been linked to adverse health and cognitive effects [
12]. This approach ensures consistency with international literature while addressing region-specific pollution pro-files and their documented neurotoxic impacts. Our results indicated that the levels of heavy metals inside and outside the schools influence the AP of eighth-grade students. In conclusion, children in this area are exposed to high levels of environmental pollution by heavy metals, which may pose a health risk and impact their AP [
11].
Given the importance of air pollution on children’s learning and AP, we asked: What is the effect of PM2.5 air pollution on the AP of Chilean eighth-grade children? Our objective was to compare the AP of eighth-grade children living in the three most PM2.5-polluted areas of Chile with those living in the three least polluted areas of the country. Additionally, we compared the AP of schools in the most and least polluted areas according to the administrative department and we determined the effect size. Accordingly, this study contributes novel evidence on the association between PM2.5 exposure and academic performance using large-scale standardized educational data in Chile, offering new insights from a Latin American context where such research remains scarce.
4. Discussion
Using the 2019 SIMCE database, we compared the academic performance in mathematics and language of 8th-grade students attending schools in the three highest and three least PM2.5-polluted geographic areas. The results indicate lower academic performance in the SIMCE mathematics and language tests among schools located in the three most PM2.5-polluted areas compared to those in the three least polluted areas of the country. Subsequently, the SIMCE test results were compared according to the administrative dependency of the schools (private, subsidized, and municipal). Data revealed that the AP of 8th-grade students in private and municipal schools is similar when their schools are located in the three zones with the highest and lowest air pollution. In contrast, students attending subsidized private schools in the most polluted zones demonstrated significantly lower SIMCE scores compared to their counterparts in the least polluted zones. On the other hand, the effect size for the comparison between high and low pollution schools indicates a small effect (0.31 in the math SIMCE and 0.27 in the language SIMCE).
Critically elevated levels of PM
2.5 represent a serious risk to both environmental and public health, with documented impacts in various regions of Chile. Previous research has shown a strong association between chronic exposure to PM
2.5 and increased mortality, higher hospitalization rates, and a rise in respiratory and cardiovascular diseases in cities with high pollution levels [
3]. In this context, the findings of our study reinforce the evidence that the adverse effects of PM
2.5 pollution are not limited to physical health alone but also affect the academic performance of students, suggesting an even broader impact on child well-being and educational equity. Specifically, our results show that eighth-grade students attending schools in municipalities with higher PM
2.5 concentrations have lower scores on the SIMCE tests compared to those in less polluted areas. These findings highlight the need to integrate air quality as a key variable in the formulation of public policies aimed at improving educational and health conditions in communities highly exposed to air pollution.
In this context, and considering the Sixth Report on the State of the Environment in Chile, we observe that the three communes most polluted with PM
2.5 are in the southern part of the country, where there is a high residential demand for wood combustion for heating and cooking. Specifically, in the city of Coyhaique, characterized by frequent episodes of environmental pre-emergency, the geographic configuration of a semi-closed mountainous valley and large-scale atmospheric conditions also play a role, as they are natural forces that modulate lower ventilation in the basin [
17]. An interesting aspect is that the maximum concentrations of PM
2.5 established by the WHO (annual concentration of 5 µg/m
3 and 24-h concentration of 15 µg/m
3) and the national standard (annual concentration of 20 µg/m
3 and 24-h concentration of 50 µg/m
3) show a significant difference in values, demonstrating that Chile far exceeds the established standards for both annual and daily concentrations. Related to this, in terms of morbidity, an average of 3007 hospitalizations for respiratory causes could have been avoided in people of all ages if Chile adhered to the WHO standard, and 1069 if it followed the national standard, which unfortunately is sometimes also not met [
18].
Regarding AP, our results indicate that it is lower in more polluted areas across all SIMCE tests. This suggests a possible effect of PM
2.5 air pollution on student learning. In this context, Balakrishnan et al. (2021) studied the impact of air pollution on AP in language and mathematics among children aged 5 to 16 in India. Their findings indicated that high levels of air pollution significantly reduce language and mathematics scores, and that this performance decline worsens with age [
19].
As previously mentioned, prolonged exposure to PM
2.5 poses significant neurotoxic risks to children due to the ongoing development of their brains, particularly affecting the hippocampus and prefrontal cortex [
20,
21], which may result in diminished short-term memory and impaired cognitive functions, such as mathematical reasoning and critical thinking [
22]. Therefore, as the SIMCE test is based on the assessment of cognitive functions, these brain-level changes could be reflected in a decrease in AP. In this regard, schools located in areas with higher air pollution showed lower scores in mathematics, indicating reduced quantitative skills. Language were also negatively affected, possibly due to their reliance on cognitive skills related to memory and critical analysis, which may be more vulnerable to the neurotoxic effects of pollution [
23]. The findings of this research are consistent with studies conducted in other areas of Chile, such as Puchuncaví and Quintero, known as “sacrifice zones”, due to their high concentration of environmental pollutants. Parra et al. (2024) demonstrate how exposure to heavy metals from industrial pollution and traffic is associated with lower AP. In these areas, a correlation has been found between increased levels of suspended elements such as arsenic, lead, and manganese, and decreased scores in AP tests like SIMCE among eighth-grade students [
11]. This correlation highlights the importance of considering environmental factors when studying student performance in areas affected by pollution.
On the other hand, it is interesting that no significant differences in SIMCE scores were observed between private and municipal schools when comparing institutions located in zones with higher versus lower air pollution. In this regard, it is possible that not only the level of PM
2.5 pollution is influencing the AP, but also other internal and/or external variables affecting the student. One of these variables that could partially explain these differences is the SES. In this regard, when analyzing this variable in subsidized private schools, we found that in the three most polluted areas, 67.5% have low and lower-middle SES, 21.5% middle, and 9.25% upper-middle and high SES. In contrast, in the three least polluted areas, the SES distribution was 2.5% lower-middle, 32.5% middle, and 65% upper-middle SES. These differences in terms of SES found in subsidized private schools are not present in private schools, both in more and less polluted areas, where 100% of them are in the upper-middle and high SES. In municipal schools in the most polluted areas, 14% are in the middle SES, 45% in the lower-middle SES, and 20% in the low SES. Meanwhile, in the less polluted areas, 7.7% are in the upper-middle SES, 52.3% in the middle SES, and 40% in the lower-middle SES. In this regard, Lu et al. (2021) showed that higher air pollution within a specific socioeconomic group is associated with lower AP among children. The authors suggest that further improvements in air quality could enhance children’s overall AP and contribute to greater socioeconomic achievement throughout their lives [
24]. Cheeseman et al. (2022) discuss the connection between SES and pollution in their study on U.S. schools. They note that students from marginalized ethnic or racial groups attending public schools in the U.S. are more likely to be exposed to higher levels of air pollution. Public schools with higher poverty rates are also linked to increased concentrations of air pollutants. Furthermore, even within urban public schools, disparities in air pollution exposure remain across different racial and ethnic groups [
25]. In 2024, Bernardi et al. researched whether exposure to poor air quality affects AP differently among Italian students from high and low socioeconomic backgrounds. Their findings reveal a modest but consistent negative impact of PM
2.5 on math and language test scores, with the most significant effects observed in students from lower socioeconomic levels [
26]. These results suggest that the interaction between socioeconomic vulnerability and exposure to air pollutants could have additive or synergistic effects on academic performance, highlighting the need for comprehensive public policies that jointly consider environmental and social aspects in educational contexts.
Private schools (regardless of their location in areas with high or low PM2.5 pollution) predominantly include students from middle-upper and high socioeconomic levels. Municipal schools, on the other hand, mostly have students from middle, lower-middle, or low SES. Subsidized schools, meanwhile, show a wide variability in SES, which could be related to the varying degree of access to resources and tools that might complement and enhance AP. Although this study compared SIMCE results between schools in areas with higher and lower air pollution from PM2.5 within the same administrative category to control SES as a potential influencing factor, it is important to consider this aspect when analyzing AP data in students.
Regarding the differences in the 2019 SIMCE scores for eighth grade between schools with different administrative dependencies, the highest average score was observed in a private school in a polluted area, with a weighting of 290.06 points, while the lowest score was in a municipal school in a non-polluted area, with a total of 235.50 points. These differences in scores between private and municipal schools can be explained, as proposed by Ahumada et al. in 2020, based on differences in SES. Private schools are generally associated with higher socioeconomic strata than municipal schools. Factors such as access to higher-quality education, opportunities to participate in academic skill development workshops and personal development programs, learning additional languages, and better infrastructure in educational institutions may all contribute to better AP in private schools compared to schools whose students belong to middle or lower SES levels [
14].
Another phenomenon that could influence the AP of students, and which we do not know about as this information was not included in the databases we worked with, is school absenteeism. School absenteeism is a relevant quality indicator for the educational trajectory of children and youth in the country [
27]. Students who repeatedly miss classes disrupt this process, which results in a loss of continuity in the development of learning objectives covered in class. This leads to an academic lag that is reflected in lower grades [
28]. According to the Ministry of Education’s Center for Studies (MINEDUC), there is a higher percentage of students with severe absenteeism in urban areas (28% to 38%) compared to rural areas (19% to 32%), as well as a significant increase in private subsidized schools (22% to 34%) with students experiencing severe absenteeism [
27]. In this research, we found that in private subsidized schools in more polluted areas, 27% were in rural areas, while in less polluted areas, no private subsidized schools were in rural zones. In municipal schools in more polluted areas, 49% are rural, compared to only 4% in less polluted areas. As for private schools, both in more and less polluted areas, all of them are in urban zones.
Despite the significant differences reported in this research between schools with high pollution and low pollution, the results should be interpreted with caution, as the effect size was small, indicating potential limitations that may be associated with variables such as socioeconomic level, gender, vulnerability, and the lack of an individual-level analysis, which should be incorporated into future studies.
Limitations of the Study: Although it was expected that the sample of private institutions would be smaller compared to subsidized and municipal schools, a significant difference was found between the number of private schools in less contaminated areas versus those in more contaminated areas. Focusing only on private schools in the most contaminated regions [
28], the data consists of only five schools, which is a very small sample size. This could be considered a limitation of the study, as having more private schools could provide greater variability in scores, like what is observed in less contaminated areas. Nevertheless, the limited number of private schools is representative of what occurs in the country, as according to information available from the National Congress Library of Chile, in 2019 there were a total of 11,148 educational institutions in the country, of which 4879 were municipal schools (43.76%), 5599 were subsidized private schools (50.22%), and 670 were private schools (6.01%) [
29]. It is also a limitation of this study that the database does not include information on Personal and Social Development Indicators (IDPS), which would allow for an analysis of factors such as parental education, self-esteem, motivation, school climate, self-perception, and academic self-assessment, all of which can influence students’ academic performance (AP). Access to this information would help us better understand the personal and social context of the students and their families and to determine whether a relationship exists between these factors and student learning. Furthermore, the database did not include gender-specific information. If this data had been available, we could have conducted a more in-depth individual analysis to explore whether gender influences AP. The absence of gender-related data prevents the exploration of potential differences in vulnerability to PM
2.5 pollution. Investigating gender differences would be of particular interest, as evidence suggests that females tend to perform better in language, while males excel in mathematics. Additionally, the data did not provide information about students’ length of residence in the studied geographic areas, exposure to noise pollution [
12,
30,
31], or whether their mothers were exposed to environmental pollutants during pregnancy.”. This information would be very useful for analyzing exposure duration and its potential effects on learning and, consequently, on students’ AP [
18].
Lastly, this study focused exclusively on PM2.5 due to its recognized neurocognitive impact and the availability of reliable nationwide data. The inclusion of other environmental factors—such as exposure to other air pollutants or water quality indicators—was beyond the scope of this study but represents an important direction for future research.