Comparison of Three Antibiotic Prophylaxis Protocols for Preventing Postoperative Infection in Tibial Plateau Fractures
, Jose Alonso Zumbado 1, Laura Morata 2, Judit MartÃnez-Peñas 3 and Oscar Ares 1Round 1
Reviewer 1 Report
Comments and Suggestions for AuthorsThis article addresses an important and still valid topic. It is worth continuing such studies based on microbiological diagnostics. However, overuse of such broad-spectrum drugs, in large-scale prophylaxis is quite risky and may lead to increased drug resistance. Therefore, such therapy should not be excessively used. In view of this, some ambiguities arise:
1. How was done the selection of antybiotics ?
2. Which factor decided which drug to apply between groups?
3. How were the groups of patients divided?
4. What was the pattern antibiotic therapy introduced in the divided groups: based on the result of the microbiological examination, or empirically?
5. Was the therapy modified after the microbiological examination based on the available results?
In addition, it is worth explaining the ASA and Schatzker classification systems in more detail. And finally, the authors' affiliations should also be completed.
Comments on the Quality of English Language
No comments.
Author Response
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Reviewer 2 Report
Comments and Suggestions for Authors
Comments for author File: Comments.pdf
Author Response
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Author Response File: Author Response.pdf
