Review Reports

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

This article addresses an important and still valid topic. It is worth continuing such studies based on microbiological diagnostics. However, overuse of such broad-spectrum drugs, in large-scale prophylaxis is quite risky and may lead to increased drug resistance. Therefore, such therapy should not be excessively used. In view of this, some ambiguities arise: 

1.  How was done the selection of antybiotics ?

2.  Which factor decided which drug to apply between groups?

3.  How were the groups of patients divided? 

4. What was the pattern antibiotic therapy introduced in the divided groups: based on the result of the microbiological examination, or empirically? 

5.  Was the therapy modified after the microbiological examination based on the available results?  

In addition, it is worth explaining the ASA and Schatzker classification systems in more detail. And finally, the authors' affiliations should also be completed.

 

Comments on the Quality of English Language

No comments.

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

  

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.pdf