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Article

Maxillary and Mandibular Third Molars Impaction with Associated Pathologies in a North Cyprus Population: A Retrospective Study

by
Bedriye Gizem Çelebioğlu Genç
1,*,
Kaan Orhan
2 and
Evren Hıncal
3
1
Department of Oral and Maxillofacial Surgery, Cyprus University of Health and Social Sciences, Morphou, TRNC, Mersin 10, Turkey
2
Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara 06560, Turkey
3
Department of Mathematics, Near East University, Nicosia, TRNC, Mersin 10, Turkey
*
Author to whom correspondence should be addressed.
Appl. Sci. 2022, 12(11), 5756; https://doi.org/10.3390/app12115756
Submission received: 18 May 2022 / Revised: 3 June 2022 / Accepted: 4 June 2022 / Published: 6 June 2022
(This article belongs to the Section Applied Dentistry and Oral Sciences)

Abstract

:
This study aimed to find out the incidence of impacted third molars and associated pathologies in people who live in the North Cyprus population. Dr. Burhan Nalbantoglu State Hospital is the only hospital that has an oral and maxillofacial surgery department among the state hospitals in North Cyprus. Patients who were referred to this department during a one-year period due to the complaints regarding their third molar were included in our study. This retrospective study involved 550 patients aged 16 to 65 years (1752 third molars). Chi-square tests were done for bilateral comparison between age, gender, and third molar (p < 0.05). Among the groups included in the study, the highest number of third molars originated from the 20–29 age group (n = 1050). Among all 1752 third molars, 716 (40%) of them erupted, while 1036 (60%) were impacted molar teeth, with significant differences between genders (p > 0.05). The most often impacted position in the mandible was the mesioangular type (42%) and in the maxilla was the vertical type (62%). Partially and completely impacted mandibular third molars showed a significant difference between the left and right sides (p < 0.05). A huge proportion of third molars are impacted in the North Cyprus population. The degree of impaction of wisdom teeth and the problems they cause should be well evaluated, and the surgical approach should be considered according to the baseline of this data.

1. Introduction

It is common for third molars to fail, erupt, and remain impacted. Impacted teeth are partially erupted or impacted teeth that cannot establish a proper relationship with other teeth and tissues in the arch despite the expiration of the eruption time. The most frequently impacted teeth in the lower and upper jaws are the third molars, and their frequency of impaction has been reported to vary between 18% and 32% [1,2,3].
There are many theories to explain the frequency of impaction of third molars. Some of these are the Mendelian theory, the phylogenic theory, and the orthodontic theory. Most of these theories emphasize the relationship between changes in dietary habits and the mismatch between jaw size and tooth size [4].
The prevalence and distribution of impacted teeth in different parts of the jaw differ in many studies. The prevalence of impacted teeth, age, eruption time of teeth, radiological tooth development, and eruption criteria are determined [4]. Many studies show that there are no gender differences in impacted third molars. However, other studies have reported a higher frequency of molars being impacted in females than in males [1,2,5,6].
Although impacted third molars are mostly asymptomatic, they can sometimes cause complications. Some of these complications can include pain, infection, cyst and tumor formation, root resorption in permanent teeth, fracture in the jaw, crowding in the mandibular anterior teeth, and bone loss in adjacent teeth [5,7,8,9,10,11,12,13,14].
Surgical removal of impacted third molars is the most common treatment method in oral surgery. However, various complications may occur during and after surgical extraction. The most common complications are pain, edema, trismus, bleeding, infection, alveolar nerve injury, displacement of the extracted tooth into neighbor spaces, and mandible fractures [15,16].
Many methods are used in the classification of impacted teeth. These classifications are made according to the level of impaction, the angle of the third molar, and its relationship with the anterior border of the mandibular ramus [8]. According to the Pell and Gregory classification system, third molars can be classified by their depth or level according to the occlusal surface (OS) of the adjacent second molar tooth [9].
There have been previous studies in Caucasian [3,10,11,13,17,18], Arab [19,20], African [21,22], and Chinese [5,12] populations regarding the impaction of mandibular third molars. However, no study has been done on the North Cyprus population. Hence, it was considered worthwhile to assess the prevalence of impacted third molars using a panoramic radiograph with the associated pathologies according to the age, gender, and type of impaction in a sample of patients living in North Cyprus.

2. Materials and Methods

This retrospective study was carried out utilizing a review of clinical records of North Cyprus patients who were referred to Dr. Burhan Nalbantoğlu State Hospital, Department of Oral and Maxillofacial Surgery clinic for a period of one year (December 2012–December 2013). Dr. Burhan Nalbantoğlu State Hospital is the only hospital that has an oral and maxillofacial surgery department among the state hospitals in North Cyprus. A total of 1752 third molars in 550 patients were included in the study.
The study started with the approval of the Turkish Republic of Northern Cyprus Ministry of Health inpatient treatment institutions (Ref: YTK0,000-6000-14/446/Approval/2014). This study was based on the retrospective evaluation of radiographs. Only archived data were used for the study. However, before taking any radiograph examinations, patients gave their informed consent before any application according to the principles of the Helsinki Declaration, including all amendments and revisions. Collected data was only accessible to the researchers.
All panoramic radiographs were taken with standardized equipment and specifications. Data regarding age, gender, number of erupted and impacted third molars, the location (mandible or maxilla), sides (left/right), and type of impaction were obtained from patients’ records, and panoramic radiographs were retrospectively assessed by a single oral and maxillofacial surgeon on a transparency projector under constant lighting conditions.
The third molars were divided into three groups: erupted, partially erupted third molars, and completely impacted third molars [3,10,11,12,13].
The angulation of the impacted third molar was documented based on Winter’s classification regarding the angle formed between the intersected longitudinal axes of the second and third molars, namely vertical impaction (10° to −10°), mesioangular impaction (11° to 79°), horizontal impaction (80° to 100°), distoangular impaction (−11° to −79°), others (111° to −80°), and buccolingual impaction (any tooth oriented in a buccolingual direction with crown overlapping the roots) [17]. The axis of the teeth was measured on panoramic radiographs obtained from the patients by using a ruler and compass (Figure 1a,b).
The pathologies and diagnoses of these pathologies associated with impacted teeth were defined in Dogan et al.’s study [3]: pericoronitis, infection of the soft tissue surrounding a partially erupted tooth; caries, a clinical cavity or radiographic lesion reaching at least to the amelodentinal junction; periodontitis, bone loss of the adjacent tooth of more than 5 mm below the cementoenamel junction that is diagnosed both radiographically and by probing the gingival pocket; abscess-cyst, lesions with a pericoronal space of the dental follicle of more than 4 mm that is verified radiographically or surgically; caries on the second molar and root resorption of the adjacent teeth, clear loss of substance in the root surface revealed radiographically.
Data collected were entered into a spreadsheet (Excel 2000; Microsoft, Redmond, DC, USA) and analyzed subsequently using Statistical Package for Social Sciences (SPSS) version 16.0. The prevalence of impacted third molars according to age, gender, and type was assessed and displayed by frequency and percentage. A p-value less than 0.05 among gender, age, and sides was considered statistically significant through the Pearson Chi-square test.

3. Results

This study included 550 patients. Of these, 248 (46%) were female and 302 (54%) were male, and a total of 1752 third molar teeth were investigated (Table 1).
The age of the patients who were the subjects of this study ranged from 16 to 65 years, with a mean age of 29 years. The highest prevalence of third molars included in this study were observed in patients belonging to the 20–29 years of age group. The total number of third molars in this group is 1050 (60%). The number of third molars included in this study decreased with increasing age (Table 2).
Among all of the 1752 third molars included in this study, 716 (40%) of them erupted, while 1036 (60%) were impacted third molar teeth. The rest of the third molars were congenitally missing or already extracted and were not seen in panoramic radiographs. Impacted teeth were divided into two groups. The first group consisted of 487 (47%) partially impacted third molars, and the second group consisted of completely impacted 549 (53%) third molar teeth. Partially and completely impacted mandibular third molars displayed a significant difference between the left and right sides (p < 0.05), whereas partially and completely impacted maxillary third molars did not display a significant difference between the left and right sides (p > 0.05). Data analysis showed that third molars had approximately the same rate of occurrence in the mandible and maxilla (932 and 820 molars). The left side of the mandible had a greater number of impactions than the right side in our study group (Table 3).
The distribution of erupted, partially impacted, and completely impacted third molars according to gender is shown in Table 4. There was no statistically significant difference between genders according to the maxillary and mandibular right and left sides (p > 0.05) (Table 4).
The patients’ data showed that 383 (21%) teeth were associated with the following pathologies: pericoronitis, caries, periodontitis, abscess or cysts, caries on the second molar, and root resorption of the adjacent teeth. Pericoronitis was observed as the most frequent pathology in both the completely impacted and partially impacted groups, with 76 (14%) and 102 (21%) cases, respectively. Caries was not diagnosed with completely impacted teeth. The number of observed caries was low, with 73 cases observed in partially erupted teeth (representing 7% of all observed pathologies) (Table 5).
Considering the distribution of pathologies by age, while pericoronitis, caries, and caries on the second molar were most common in the 30–39 age group; periodontitis, abscess-cyst, and root resorption of the adjacent teeth were most common in the 40–49 age group (Table 6).
Among the impacted mandibular third molars, the majority of the patients had mesioangular impaction (42%), and only 4% of the patients had distoangular impaction. Contrary vertical impaction was the most common type in the maxillary arch (62%), and horizontal impaction was the least prevalent type (3%) (Table 7).
While symptoms were observed in 144 (26%) of the completely impacted third molars, symptoms were observed in 239 (49%) of the partially impacted third molars. When we compare the completely impacted and partially impacted teeth with each other in terms of symptoms, we see that the number of asymptomatic teeth is higher in both groups (Table 8).

4. Discussion

Impacted teeth are teeth that cannot be found in the normal position in the mouth, have not erupted, usually cause pathology, and need to be treated. All permanent teeth may remain impacted in the dental arch. The most impacted are mandibular and maxillary third molars, maxillary canine, and mandibular and maxillary second premolar and maxillary central incisors [4]. Since mandibular third molars are the most frequently impacted teeth, their operations are also the most common procedure in maxillofacial surgery [15,16,23,24,25].
This retrospective study to assess the prevalence of impacted third molars among the North Cyprus population included 550 patients. In this study, standard clinical radiographic findings were used from patients during a routine examination. A total of 1752 third molars were found in 550 patients. Of all teeth, 740 of the teeth were from female patients, while 1012 were teeth from male patients. Males tend to have a higher incidence of impacted third molars (p > 0.05). The male to female ratio was 302:248 (1.21:1), with a p-value of 0.897, which is not statistically significant. Our male to female ratio of impacted molars is similar to the other studies [3,26,27].
The age group in which the third molars were impacted the most was the 20–29 years age group (62%), with the rate of impacted molars decreasing as the age increases. This is similar to other studies and is widely seen when the literature is searched [4,26,28]. The reason for this may be that the third molars tend to cause problems in an earlier period of life, and therefore the related teeth are often surgically extracted in an earlier period of life.
Observed impacted third molars were more impacted in the mandibular arch than in the maxillary arch in both genders. The ratio of mandibular third molar (n = 932) to maxillary third molar (n = 820) was 1.13:1. The greater incidence of impaction in the lower jaw may be due to the more compactness of the bone structure in the mandible.
Third molar impaction is a common problem affecting a large proportion of the population throughout the world. In this study, the incidence of impacted third molars in the North Cyprus population was estimated at 59% (1036/1752). The reported incidence in the present research is higher than published research in the Southeast region [20,29,30]; on the other hand, it is less than published research in the United States of America and Singapore [5,31,32]. This difference may be due to genetic and racial differences, which are two important factors in tooth impaction.
Impacted mandibular third molar teeth were mostly found in the mesioangular position (42%) and were least observed in the distoangular (4%) position. In the maxillary arch, the most common type was vertical impaction (62%), and the least common type was horizontal impaction (3%). According to reports from Pakistan, the USA, Nigeria, China, Thailand, Spain, and Malaysia, the most common impaction type is mesioangular in the maxilla. However, other studies have shown that vertical impaction is the most common impaction type in maxilla, similar to our findings [1,5].
It is controversial whether impacted teeth can cause root resorption of the adjacent teeth. In our study, we found that 21 teeth (2%) showed root resorption of the adjacent teeth. This value was lower than the study of Nitzan [23] but higher than the study of Yamaoka [18].
Findings in this study indicated that pericoronitis was the most common symptom for the third molars. However, a significant portion of the partially impacted (60%) and completely impacted (73%) third molars appear to be asymptomatic.
A limitation of this study is that it only considered one health center. The wide age range of the people included in the study may suggest that the results of the study are not representative of the general population. However, the primary aim of this study was to investigate the frequency of impacted teeth in patients attending our department. It should also be noted that a large sample population should be considered for further studies with additional parameters such as symptoms of third molars.

5. Conclusions

A huge proportion of third molars are impacted in the North Cyprus population. The degree of impaction of wisdom teeth and the problems they cause should be well evaluated, and the surgical approach should be considered according to the baseline of this data. Such a study has never been done in North Cyprus before. Therefore, this study helps in revealing the impact rate on the population and will be of further use in guiding larger subsequent studies.

Author Contributions

B.G.Ç.G. was a principal investigator and a major contributor to data collection, data entry, manuscript writing, and literature search. K.O. was a co-investigator and supervisor of the study. E.H. was a co-investigator and a major contributor to statistics. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

The study was conducted following the Declaration of Helsinki, and approved by the Institutional Review Board of the TRNC Ministry of Health inpatient treatment institutions (Ref: YTK0,000-6000-14/446/Approval/2014).

Informed Consent Statement

Informed consent was obtained from all subjects involved in the study.

Data Availability Statement

The data sets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.

Acknowledgments

We would like to thank all the participants who cooperated with us and contributed to the creation of the study.

Conflicts of Interest

The authors declare no conflict of interest.

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Figure 1. (a) Vertical and horizontal impaction; (b) Mesioangular and distoangular impaction.
Figure 1. (a) Vertical and horizontal impaction; (b) Mesioangular and distoangular impaction.
Applsci 12 05756 g001
Table 1. Distribution of the number and ratio of the patients’ gender.
Table 1. Distribution of the number and ratio of the patients’ gender.
GenderNumber of PatientsRatio of Patients
Female24846%
Male30254%
Total550100%
Table 2. Age and gender distribution of patients with third molar numbers.
Table 2. Age and gender distribution of patients with third molar numbers.
GenderAge Group (Years)
16–1920–2930–3940–4950–5960–65Total
FEMALE third molar number110389125832310740
MALE third molar number746611756320191012
TOTAL third molar number184105030014643291752
Table 3. Distribution of erupted, partially impacted, and completely impacted third molars.
Table 3. Distribution of erupted, partially impacted, and completely impacted third molars.
Number of Third Molars (n)p-Value
Side of the Third MolarErupted
(n = 716)
Partially Impacted
(n = 487)
Completely Impacted
(n = 549)
Maxilla right26641106p > 0.05
Maxilla left24641120
Mandible right10120869p < 0.05
Mandible left103197254
Total7161036
Table 4. Distribution of erupted, partially impacted, and completely impacted third molars according to gender. There is no significant difference between males and females (p > 0.05).
Table 4. Distribution of erupted, partially impacted, and completely impacted third molars according to gender. There is no significant difference between males and females (p > 0.05).
Number of Third Molars (n)p-Value
Side and LocationFemaleMale
Maxilla right172241p > 0.05
Maxilla left172235
Mandible right193270p > 0.05
Mandible left203266
Total7401012
Table 5. Distribution of pathologies associated with partially and completely impacted third molars.
Table 5. Distribution of pathologies associated with partially and completely impacted third molars.
PathologiesCompletely Impacted Third Molar (n = 549)Partially Impacted Third Molar (n = 487)Total Number of Partially and Completely Impacted Third Molar (n = 1036)
Pericoronitis76 (14%)102 (21%)178 (17%)
Caries-73 (15%)73 (7%)
Periodontitis16 (3%)27 (6%)43 (4%)
Abscess-Cysts21 (4%)14 (3%)35 (3%)
Caries on the second molar18 (3%)15 (3%)33 (3%)
Root resorption of the adjacent teeth13 (2%)8 (1%)21 (2%)
Number of pathologies in completely impacted third molars = 144Number of pathologies in partially impacted third molars = 239Total number of pathologies in partially and completely impacted third molars = 383
Table 6. Distribution of pathologies occurring in third molars according to age.
Table 6. Distribution of pathologies occurring in third molars according to age.
PathologiesNumber and Percentage of Patients by Age Group (%)
16–1920–2930–3940–4950–5960–65Total
(n = 98)(n = 720)(n = 150)(n = 40)(n = 14)(n = 14)(n = 1036)
Pericoronitis12 (12%)127 (17%)33 (22%)5 (12%)1 (7%)178 (17%)
Caries2 (5%)19 (2%)39 (26%)10 (25%)2 (14%)1 (7%)73 (7%)
Periodontitis14 (1%)13 (8%)12 (30%)4 (28%)43 (4%)
Abscess-Cysts1 (0%)23 (15%)10 (25%)1 (7%)35 (3%)
Caries on the second molar21 (2%)10 (6%)2 (5%)33 (3%)
Root resorption of the adjacent teeth4 (0%)10 (6%)7 (17%)21 (2%)
Table 7. Distribution of impacted maxillary and mandibular third molars by type.
Table 7. Distribution of impacted maxillary and mandibular third molars by type.
Impacted Maxillary Third MolarsImpacted Mandibular Third Molars
Vertical type62%30%
Mesioangular type33%42%
Distoangular type2%4%
Horizontal type3%23%
Table 8. Distribution of completely impacted and partially impacted third molars with and without symptoms.
Table 8. Distribution of completely impacted and partially impacted third molars with and without symptoms.
Completely Impacted Third Molar (n = 549)Partially Impacted Third Molar (n = 487)Total (n = 1036)
Symptoms144 (26%)239 (49%)383 (37%)
Without symptoms405 (73%)248 (50%)653 (63%)
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Genç, B.G.Ç.; Orhan, K.; Hıncal, E. Maxillary and Mandibular Third Molars Impaction with Associated Pathologies in a North Cyprus Population: A Retrospective Study. Appl. Sci. 2022, 12, 5756. https://doi.org/10.3390/app12115756

AMA Style

Genç BGÇ, Orhan K, Hıncal E. Maxillary and Mandibular Third Molars Impaction with Associated Pathologies in a North Cyprus Population: A Retrospective Study. Applied Sciences. 2022; 12(11):5756. https://doi.org/10.3390/app12115756

Chicago/Turabian Style

Genç, Bedriye Gizem Çelebioğlu, Kaan Orhan, and Evren Hıncal. 2022. "Maxillary and Mandibular Third Molars Impaction with Associated Pathologies in a North Cyprus Population: A Retrospective Study" Applied Sciences 12, no. 11: 5756. https://doi.org/10.3390/app12115756

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