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Review

Antimicrobials in Dentistry

by 1,2, 3,4 and 1,*
1
Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London, Guy’s Hospital, London SE1 9RT, UK
2
Department of Restorative Dental Science, King Saud bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia
3
Instituto de Ciencia y Tecnología de Polímeros, Consejo Superior de Investigaciones Científicas, 28006 Madrid, Spain
4
Consorcio Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, 28029 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Gianrico Spagnuolo
Appl. Sci. 2021, 11(7), 3279; https://doi.org/10.3390/app11073279
Received: 20 January 2021 / Revised: 30 March 2021 / Accepted: 1 April 2021 / Published: 6 April 2021
(This article belongs to the Special Issue Advances in Antimicrobial Sustainable Polymers)
Dental caries (decay) is caused by pathogenic bacterial species, which afflicts nearly a third of the world’s population from early childhood to old age. Treatment of tooth decay often involves the use of filling materials to restore the cavity; however, if untreated, it can cause pain, infection and eventually lead to tooth loss. Since the oral environment is colonised by many different microorganisms, bacterial biofilms can form on these filling materials, contributing to secondary caries that can eventually lead to the failure of the dental restoration. Thus, preventing the formation of bacterial biofilms is an important strategy in the management of caries, which has led to research enabling antimicrobial capabilities in dental materials. Materials and pharmaceutical sciences are in a continuous race against microbial resistance but are trying to balance between beneficial biota associated with the oral cavity, and, of course, avoiding a harmful effect on tissues is challenging. This has, therefore, stemmed a substantial interest in both preventive and restorative measures that would enable limiting the formation of secondary caries, oral microbial biofilms, and the retention of tooth mineral. Thus, innovative strategies are being explored and here we present a review with a focus on strategies that can inhibit or limit the formation of bacterial biofilms. View Full-Text
Keywords: antibacterial monomers; dental materials; bactericidal; dentistry antibacterial monomers; dental materials; bactericidal; dentistry
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MDPI and ACS Style

Alkattan, R.; Rojo, L.; Deb, S. Antimicrobials in Dentistry. Appl. Sci. 2021, 11, 3279. https://doi.org/10.3390/app11073279

AMA Style

Alkattan R, Rojo L, Deb S. Antimicrobials in Dentistry. Applied Sciences. 2021; 11(7):3279. https://doi.org/10.3390/app11073279

Chicago/Turabian Style

Alkattan, Rana, Luis Rojo, and Sanjukta Deb. 2021. "Antimicrobials in Dentistry" Applied Sciences 11, no. 7: 3279. https://doi.org/10.3390/app11073279

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