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Polyacrylonitrile Nanofibers Containing Viroblock as Promising Material for Protective Clothing

Nanotechnology Research Group, Department of Textile & Clothing, Faculty of Engineering and Technology, National Textile University Karachi Campus, Karachi 74900, Pakistan
Nano Fusion Technology Research Group, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda 386-8567, Nagano, Japan
School of Textile—Leather and Fashion, Hanoi University of Science and Technology, Hanoi 10000, Vietnam
Alkaram Textile Mills Pvt. Ltd., Karachi 75120, Pakistan
Department of Design, School of Art & Design, National Textile University, Faisalabad 37610, Pakistan
Authors to whom correspondence should be addressed.
Both authors have equal contribution.
Academic Editor: Sergio Torres-Giner
Appl. Sci. 2021, 11(23), 11469;
Received: 9 November 2021 / Revised: 30 November 2021 / Accepted: 1 December 2021 / Published: 3 December 2021
(This article belongs to the Topic Sustainable Polymer Technologies)
Antimicrobial viroblock/polyacrylonitrile nanofiber webs fabricated using the electrospinning method were assessed in terms of the antimicrobial activity against infectious agents as a potential material used in mask production. Viroblock (VB) is an amalgam of lipid vesicle and silver. Lipid vesicle depletes the virus outer membrane, which contains cholesterol, while silver ions penetrate the virus, interact with sulfur-bearing moieties, and possess the virus bactericidal property. VB, having anti-coronavirus and anti-influenza properties, was prepared in four different concentrations, 0.5 wt%, 1 wt%, 1.5 wt%, and 2 wt%, in regard to nanofiber weight. The resultant nanofibers were characterized by scanning electron microscope (SEM), Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), water contact angle, water content, and thermogravimetric analysis (TGA). Moreover, all nanofibrous samples were evaluated for cell proliferation assay and ATCC antibacterial tests. Based on characterization results and cytotoxicity, the developed composite nanofibers-based webs showed good promise for utilization in anti-viral masks. Particularly, 2 wt% VB/PAN nanofibers have the highest antibacterial properties against negative and positive bacteria along with excellent cell viability. View Full-Text
Keywords: antimicrobial; antiviral; viroblock; nanofibers; cell viability antimicrobial; antiviral; viroblock; nanofibers; cell viability
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MDPI and ACS Style

Hussain, M.; Salam, A.; Arain, M.F.; Ullah, A.; Dao, A.-T.; Vu-Manh, H.; Phan, D.-N.; Ansari, A.S.; Khan, M.Q.; Javed, Z.; Kim, I.-S. Polyacrylonitrile Nanofibers Containing Viroblock as Promising Material for Protective Clothing. Appl. Sci. 2021, 11, 11469.

AMA Style

Hussain M, Salam A, Arain MF, Ullah A, Dao A-T, Vu-Manh H, Phan D-N, Ansari AS, Khan MQ, Javed Z, Kim I-S. Polyacrylonitrile Nanofibers Containing Viroblock as Promising Material for Protective Clothing. Applied Sciences. 2021; 11(23):11469.

Chicago/Turabian Style

Hussain, Mujtaba, Abdul Salam, Muhammad F. Arain, Azeem Ullah, Anh-Tuan Dao, Hai Vu-Manh, Duy-Nam Phan, Aamir S. Ansari, Muhammad Q. Khan, Zafar Javed, and Ick-Soo Kim. 2021. "Polyacrylonitrile Nanofibers Containing Viroblock as Promising Material for Protective Clothing" Applied Sciences 11, no. 23: 11469.

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