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Review

Nanotechnology, Nanomedicine, and the Kidney

1
Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
2
Medical and Research Services, Greater Los Angeles Veterans Affairs Healthcare System at Sepulveda, North Hills, CA 91343, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Pablo Guardia
Appl. Sci. 2021, 11(16), 7187; https://doi.org/10.3390/app11167187
Received: 30 June 2021 / Revised: 22 July 2021 / Accepted: 28 July 2021 / Published: 4 August 2021
(This article belongs to the Special Issue Nanomaterials in Medical Engineering)
The kidneys are vital organs performing several essential functions. Their primary function is the filtration of blood and the removal of metabolic waste products as well as fluid homeostasis. Renal filtration is the main pathway for drug removal, highlighting the importance of this organ to the growing field of nanomedicine. The kidneys (i) have a key role in the transport and clearance of nanoparticles (NPs), (ii) are exposed to potential NPs’ toxicity, and (iii) are the targets of diseases that nanomedicine can study, detect, and treat. In this review, we aim to summarize the latest research on kidney-nanoparticle interaction. We first give a brief overview of the kidney’s anatomy and renal filtration, describe how nanoparticle characteristics influence their renal clearance, and the approaches taken to image and treat the kidney, including drug delivery and tissue engineering. Finally, we discuss the future and some of the challenges faced by nanomedicine. View Full-Text
Keywords: nanomedicine; nanotechnology; nanoparticle; kidney; renal imaging; tissue engineering; drug delivery nanomedicine; nanotechnology; nanoparticle; kidney; renal imaging; tissue engineering; drug delivery
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MDPI and ACS Style

Hauser, P.V.; Chang, H.-M.; Yanagawa, N.; Hamon, M. Nanotechnology, Nanomedicine, and the Kidney. Appl. Sci. 2021, 11, 7187. https://doi.org/10.3390/app11167187

AMA Style

Hauser PV, Chang H-M, Yanagawa N, Hamon M. Nanotechnology, Nanomedicine, and the Kidney. Applied Sciences. 2021; 11(16):7187. https://doi.org/10.3390/app11167187

Chicago/Turabian Style

Hauser, Peter V., Hsiao-Min Chang, Norimoto Yanagawa, and Morgan Hamon. 2021. "Nanotechnology, Nanomedicine, and the Kidney" Applied Sciences 11, no. 16: 7187. https://doi.org/10.3390/app11167187

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