Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles
Abstract
:1. Introduction
2. Polymer Coated MSNs for Cancer
3. Polymer Coated MSNs for Neurodegenerative Diseases
4. Polymer Coated MSNs for Inflammation
5. Polymer Coated MSNs for Infectious Diseases
6. Polymer Coated MSNs for Bone Related Disorders
7. Polymer Coated MSNs for Gene Delivery
8. Polymer Coated MSNs for Diabetes
9. Polymer Coated MSNs for Imaging
10. Toxicity Aspects of Polymers
11. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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S. No | Title | Submission Date | Identifier | Recruitment Status |
---|---|---|---|---|
1 | Plasmonic Photothermal Therapy of Flow-Limiting Atherosclerotic Lesions with Silica-Gold Nanoparticles: a First-in-Man Study | 30 December 2010 | NCT01270139 | Completed |
2 | Targeted Silica Nanoparticles for Real-Time Image-Guided Intraoperative Mapping of Nodal Metastases | 3 April 2014 | NCT02106598 | Recruiting |
3 | Molecular Phenotyping and Image-Guided Surgical Treatment of Prostate Cancer Using Ultra small Silica Nanoparticles | 18 November 2019 | NCT04167969 | Recruiting |
Sr No | Investigators | Silica Core | Polymer Used | Drug | Application |
---|---|---|---|---|---|
1 | Li et al. [20] | MSNs | Polydopamine | DOX | Cancer |
2 | Rahoui et al. [21] | Gold modified MSNs | Polydopamine | DOX | Cancer |
3 | Yang et al. [22] | MSNs | Polydopamine, PEG and EpCAM aptamer | DM-1 | Colorectal cancer |
4 | Chai et al. [26] | MoSe2 wrapped MSNs | Polydopamine | DOX | Cancer |
5 | Cheng et al. [27] | MSNs | Alpha-tocopheryl polyethylene glycol 1000 succinate functionalized polydopamine | DOX | Cancer |
6 | Szegedi et al. [28] | KIL-2 and KIT-6 | k-Carrageenan and Chitosan | Curcumin | Cancer |
7 | Hu et al. [29] | MSNs | Folic acid modified Chitosan and Hyaluronic acid | DOX | Cancer |
8 | Iraji et al. [30] | MSNs | Chitosan | Gallic acid | Cancer |
9 | Mu et al. [31] | MSNs | Poly-(L-Histidine) and PEG | Sorafenib | Cancer |
10 | Hegazy et al. [35] | Core-shell magnetic MSNs | Poly(N-isopropylacrylamide) (PNIPAAm) | DOX | Cancer |
11 | Feng et al. [36] | MSNs | Poly(N-Isopropylacrylamide-co-methacrylic acid) and DSPE-PEG2000 | Evodiamine and Berberine | Cancer |
12 | Du et al. [37] | MSNs | Poly(L-lysine) and Hyaluronic acid | Glucose Oxidase and Paclitaxel | Cancer |
13 | Yuan et al. [38] | MSNs | Sodium Alginate | DOX | Cancer |
14 | Avedian et al. [39] | Fe3O4 core MSNs | Polyethyleneimine and Folic acid | Erlotinib | Cancer |
15 | Moreira et al. [43] | Gold core MSNs | Poly-2-ethyl-2-oxazoline | DOX | Cancer |
16 | Yu et al. [44] | MSNs | 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acrylate polymer | DOX | Cancer |
17 | Liu et al. [45] | MSNs | Lipid Galactosyl-Ceramide | Hydroxy-campothecine | Cancer |
18 | Ma et al. [46] | MSNs encapsulated in liposomes | Calcium Phosphate | DOX and Zinc Phthalocyanine | Cancer |
19 | Liu et al. [41] | Gold Nanorods coated with Mesoporous silica | β-cyclodextrin and (2,3-dimethylmaleic anhydride modified chitosan oligosaccharide-b-poly(ethylene glycol)) | Indocyanine Green dye | Cancer |
20 | Lin et al. [32] | Highly ordered MSNs | PEGylated Lipid bilayer | Paclitaxel and Curcumin | Cancer |
21 | Kienzle et al. [33] | Dendritic MSNs | Polyethylene imine and Poly ethylene glycol | TNF-α | Cancer |
22 | Lee et al. [34] | Chlorin-e6 loaded MSNs | PEG | DOX | Cancer |
23 | Tao et al. [42] | MSNs encapsulated in liposomes | Poly(acrylic acid) | Arsenic trioxide | Glioma |
24 | Tzankov et al. [47] | MCM-41 | Chitosan and Sodium alginate | Pramipexole | Neuroblastoma |
25 | Shen et al. [48] | MSNs | Poly(lactic acid) | Resveratrol | Parkinson’s disease |
26 | Cheng et al. [49] | MSNs | plasmid RhoG-DsRed | Curcumin | Oxidative stress |
27 | Mandic et al. [50] | MSNs | PEG | Quercetin, myricetin and myricitrin | Oxidative stress |
28 | Peralta et al. [51] | MSNs | Poly(N-isopropylacrylamide-co-3-(methacryloxypropyl) trimethoxysilane) | Ibuprofen | Inflammation |
29 | Gulin-Sarfaz et al. [52] | MSNs | PEI and PEG | Dexamethasone | Pulmonary Inflammation |
30 | Popova et al. [53] | SBA-15 and MCM- 41 | Eudragit S and Eudragit RL | Sulfasalazine | inflammatory bowel disease |
31 | Liu et al. [54] | Gold nanorods coated mesoporous silica | PEG | Indocyanine green | Light-induced imaging-guided cancer therapy |
32 | Tran et al. [55] | FITC-MSNs | Polydopamine and Graphene oxide | Cisplatin | Theranostic Cancer therapy |
33 | Xu et al. [56] | MSNs | Poly Curcumin | DOX | Theranostic Cancer therapy |
34 | Song et al. [57] | SBA-15 | Polydopamine | Silver | Antibacterial therapy |
35 | Lehi et al. [58] | SBA-15 nanowishkers | Tannic acid | Metronidazole | Trichomonasis |
36 | Tamanna et al. [59] | MSNs | Nafion Polymer | Gentamicin | Immunoassay |
37 | Zhang et al. [60] | Lithium Doped Silica Nanospheres | Polydopamine | Polyetherether ketone implant | Bone regeneration |
38 | Sun et al. [61] | MSNs | Distearoyl phosphatidylcholine | Rhodamine- B | Osteoarthritis |
39 | Ngamcherdtrakul et al. [62] | MSNs | PEI and PEG | siRNA | Gene Delivery |
40 | Zarei et al. [63] | Phosphonate modified MSNs | PEI | Plasmid DNA and chlooquine | Gene delivery |
41 | Zhang et al. [64] | Lanthanide doped upconversion Silica nanoparticles | PEG | siRNA and hypocrellin A | Gene delivery |
42 | Esmaeli et al. [65] | MCM-41 | PAMAM dendrimer and chitosan-gelatine scaffold | Insulin and cinnamaldeyde | Diabetes |
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Bansal, K.K.; Mishra, D.K.; Rosling, A.; Rosenholm, J.M. Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles. Appl. Sci. 2020, 10, 289. https://doi.org/10.3390/app10010289
Bansal KK, Mishra DK, Rosling A, Rosenholm JM. Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles. Applied Sciences. 2020; 10(1):289. https://doi.org/10.3390/app10010289
Chicago/Turabian StyleBansal, Kuldeep K., Deepak K. Mishra, Ari Rosling, and Jessica M. Rosenholm. 2020. "Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles" Applied Sciences 10, no. 1: 289. https://doi.org/10.3390/app10010289
APA StyleBansal, K. K., Mishra, D. K., Rosling, A., & Rosenholm, J. M. (2020). Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles. Applied Sciences, 10(1), 289. https://doi.org/10.3390/app10010289