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Open AccessArticle

Inflammation and Trauma-Related Psychopathology in Syrian and Iraqi Refugees

1
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 48201, USA
2
Nutrition and Food Science, Wayne State University, Detroit, MI 48201, USA
3
Department of Psychology, Wayne State University, Detroit, MI 48201, USA
4
Institute of Gerontology, Wayne State University, Detroit, MI 48201, USA
*
Author to whom correspondence should be addressed.
Behav. Sci. 2020, 10(4), 75; https://doi.org/10.3390/bs10040075
Received: 4 March 2020 / Revised: 2 April 2020 / Accepted: 4 April 2020 / Published: 7 April 2020
Refugees experience high rates of post-traumatic stress disorder (PTSD), anxiety, and depression due to exposure to civilian war trauma and forced migration. Inflammatory products may offer viable biological indicators of trauma-related psychopathology in this cohort, promoting rapid and objective assessment of psychopathology. Incoming Syrian and Iraqi refugees (n = 36) ages 18–65 completed self-report measures of PTSD, anxiety, and depression and provided saliva samples during an assessment at a primary care clinic within the first month of resettlement in the United States. Interleukin 1β (IL-1β) and C-reactive protein (CRP) differentially correlated with symptom severity by domain, and there was a non-significant trend for sex moderating the relation between inflammation and PTSD symptoms. Our findings show unique relations between trauma-related psychopathology and inflammation. There is a need for further research in diverse ethnic cohorts with differential trauma exposures for inflammation to be considered a biological indicator of psychopathology. View Full-Text
Keywords: refugees; inflammation; trauma; psychopathology; anxiety; PTSD; depression refugees; inflammation; trauma; psychopathology; anxiety; PTSD; depression
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Grasser, L.R.; Burghardt, P.; Daugherty, A.M.; Amirsadri, A.; Javanbakht, A. Inflammation and Trauma-Related Psychopathology in Syrian and Iraqi Refugees. Behav. Sci. 2020, 10, 75.

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