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Review

Antimicrobial Resistance in European Companion Animals Practice: A One Health Approach

by
Helena I. G. Monteiro
1,
Vanessa Silva
1,2,3,4,
Telma de Sousa
1,2,3,4,
Rita Calouro
1,5,
Sónia Saraiva
1,6,7,
Gilberto Igrejas
2,3,4 and
Patrícia Poeta
1,6,7,8,*
1
MicroART-Antibiotic Resistance Team, Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
2
Department of Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
3
Functional Genomics and Proteomics Unit, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
4
Associated Laboratory for Green Chemistry, University NOVA of Lisbon, 1099-085 Caparica, Portugal
5
Polytechnic Institute of Santarém, School of Agriculture, Quinta do Galinheiro, 2001-904 Santarém, Portugal
6
Veterinary and Animal Research Centre, Associate Laboratory for Animal and Veterinary Science (AL4AnimalS), University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
7
CECAV—Veterinary and Animal Research Centre, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal
8
Department of Veterinary Sciences, School of Agricultural and Veterinary Sciences, University of Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal
*
Author to whom correspondence should be addressed.
Animals 2025, 15(12), 1708; https://doi.org/10.3390/ani15121708 (registering DOI)
Submission received: 7 April 2025 / Revised: 5 May 2025 / Accepted: 4 June 2025 / Published: 9 June 2025

Simple Summary

Antimicrobial resistance is a significant global public health concern, and the role of companion animals in its spread cannot be overlooked. Sharing many of the same antibiotic classes as humans and living in close proximity to them, these animals present a serious risk of the transmission of antimicrobial-resistant bacteria and resistance genes between species. Resistance proportions have reached concerning levels, including up to 50% in cats in Denmark and 40% in dogs in France. However, current EU policies remain insufficient to address this situation. The absence of a mandatory, harmonized surveillance system across Europe has created a significant gap in the data and understanding, hindering effective monitoring and control efforts. The growing emergence of multidrug-resistant strains in small animals further highlights the urgent need for targeted veterinary interventions. To address this problem effectively, the EU must adopt stronger, more unified policies within a comprehensive One Health framework that recognizes the interconnectedness of human, animal, and environmental health.

Abstract

Antimicrobial resistance (AMR) is a global health emergency. The growing levels of multidrug-resistant bacteria in companion animals represent a critical but under-recognized threat, as pets can act as reservoirs and vectors of resistant pathogens, and bacteria can spread between species. Despite living in close proximity to humans and sharing many of the same antibiotic classes, companion animals remain largely overlooked in the AMR control strategies. A major obstacle to combating AMR in Europe is the absence of a mandatory and uniform surveillance system. Without a standardized approach, data collection remains inconsistent, leading to knowledge gaps and hindering effective investigation and policymaking. Surveillance failures prevent a comprehensive understanding of resistance patterns, making it difficult to implement timely and evidence-based measures. Existing laws and regulations are insufficient to contain the growing threat of AMR. Current policies fail to enforce strict antimicrobial stewardship across all European countries and lack the necessary scope to address resistance effectively. Urgent action is required—Europe must implement stronger, harmonized surveillance systems, enforce stricter veterinary antimicrobial regulations, and develop more active and binding programs to curb resistance before it reaches an uncontrollable level. A One Health approach, recognizing the interconnectedness of human, animal, and environmental health, is essential.
Keywords: veterinary medicine; antibiotics; antibiotic resistance; companion animals; humans; One Health veterinary medicine; antibiotics; antibiotic resistance; companion animals; humans; One Health

Share and Cite

MDPI and ACS Style

Monteiro, H.I.G.; Silva, V.; de Sousa, T.; Calouro, R.; Saraiva, S.; Igrejas, G.; Poeta, P. Antimicrobial Resistance in European Companion Animals Practice: A One Health Approach. Animals 2025, 15, 1708. https://doi.org/10.3390/ani15121708

AMA Style

Monteiro HIG, Silva V, de Sousa T, Calouro R, Saraiva S, Igrejas G, Poeta P. Antimicrobial Resistance in European Companion Animals Practice: A One Health Approach. Animals. 2025; 15(12):1708. https://doi.org/10.3390/ani15121708

Chicago/Turabian Style

Monteiro, Helena I. G., Vanessa Silva, Telma de Sousa, Rita Calouro, Sónia Saraiva, Gilberto Igrejas, and Patrícia Poeta. 2025. "Antimicrobial Resistance in European Companion Animals Practice: A One Health Approach" Animals 15, no. 12: 1708. https://doi.org/10.3390/ani15121708

APA Style

Monteiro, H. I. G., Silva, V., de Sousa, T., Calouro, R., Saraiva, S., Igrejas, G., & Poeta, P. (2025). Antimicrobial Resistance in European Companion Animals Practice: A One Health Approach. Animals, 15(12), 1708. https://doi.org/10.3390/ani15121708

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